ZA885540B - Purification of human interleukin-4 expressed in escherichia coli - Google Patents

Purification of human interleukin-4 expressed in escherichia coli

Info

Publication number
ZA885540B
ZA885540B ZA885540A ZA885540A ZA885540B ZA 885540 B ZA885540 B ZA 885540B ZA 885540 A ZA885540 A ZA 885540A ZA 885540 A ZA885540 A ZA 885540A ZA 885540 B ZA885540 B ZA 885540B
Authority
ZA
South Africa
Prior art keywords
purification
expressed
escherichia coli
human interleukin
interleukin
Prior art date
Application number
ZA885540A
Other languages
English (en)
Inventor
Robert A Kastelein
A Kastelein Robert
Anita M A Van Kimmenade
M A Van Kimmenade Anita
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of ZA885540B publication Critical patent/ZA885540B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA885540A 1987-07-29 1988-07-28 Purification of human interleukin-4 expressed in escherichia coli ZA885540B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7966687A 1987-07-29 1987-07-29

Publications (1)

Publication Number Publication Date
ZA885540B true ZA885540B (en) 1989-04-26

Family

ID=22152026

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA885540A ZA885540B (en) 1987-07-29 1988-07-28 Purification of human interleukin-4 expressed in escherichia coli

Country Status (6)

Country Link
EP (1) EP0301835A1 (de)
KR (1) KR890701759A (de)
AU (1) AU2257488A (de)
IL (1) IL87270A0 (de)
WO (1) WO1989001046A1 (de)
ZA (1) ZA885540B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988004667A1 (en) * 1986-12-19 1988-06-30 Immunex Corporation Human interleukin-4 muteins
US5260202A (en) * 1988-09-07 1993-11-09 Delta Biotechnology Limited Fermentation method
AU664021B2 (en) * 1990-09-05 1995-11-02 Natinco Nv Solubilization of proteins in active forms
US5494662A (en) * 1992-04-27 1996-02-27 Ono Pharmaceutical Co., Ltd. Stimulator for bone formation
AU4665193A (en) * 1992-07-02 1994-01-31 Pitman-Moore, Inc. A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein
US6737513B1 (en) 1996-06-07 2004-05-18 Icos Corporation Macrophage derived chemokine (MDC) and chemokine analogs and assay to identify modulators of MDC activity, and therapeutic uses for same
US7018627B1 (en) 1995-06-07 2006-03-28 Icos Corporation Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof
US6498015B1 (en) 1995-06-07 2002-12-24 Icos Corporation Methods of identifying agents that modulate the binding between MDC and an MDC receptor
TR199802584T2 (xx) 1996-06-11 1999-03-22 Boehringer Mannheim Gmbh Denat�re proteinin aktive edilmesi i�in y�ntem.
EP1314739A1 (de) * 2001-11-22 2003-05-28 Bayer Ag Verfahren zur Renaturierung rekombinanter, Disulfid-enthaltender Proteine bei hohen Proteinkonzentrationen in Gegenwart von Aminen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE55163B1 (en) * 1982-06-07 1990-06-20 Celltech Ltd A process for the preparation of chymosin
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
IL80678A (en) * 1985-11-19 1999-05-09 Schering Biotech Corp Human interleukin-4

Also Published As

Publication number Publication date
KR890701759A (ko) 1989-12-21
EP0301835A1 (de) 1989-02-01
WO1989001046A1 (en) 1989-02-09
AU2257488A (en) 1989-03-01
IL87270A0 (en) 1988-12-30

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