ZA888558B - Imidazoquinoxaline compounds,their preparations and use - Google Patents

Imidazoquinoxaline compounds,their preparations and use

Info

Publication number: ZA888558B
Authority: ZA; South Africa
Prior art keywords: preparations; imidazoquinoxaline compounds; chem; compounds; imidazoquinoxaline
Prior art date: 1987-12-08

Application number

ZA888558A

Other languages

English (en)

Inventor

Holger Claus Hansen

Claus Hansen Holger

Frank Waetjen

Waetjen Frank

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-08

Filing date

1988-11-16

Publication date

1989-08-30

1988-11-16 Application filed by Ferrosan As filed Critical Ferrosan As

1989-08-30 Publication of ZA888558B publication Critical patent/ZA888558B/xx

Links

YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical class N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
229940125681 anticonvulsant agent Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
210000004556 brain Anatomy 0.000 abstract 1
230000003920 cognitive function Effects 0.000 abstract 1
239000003326 hypnotic agent Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA888558A 1987-12-08 1988-11-16 Imidazoquinoxaline compounds,their preparations and use ZA888558B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK642287A DK160876C (da)	1987-12-08	1987-12-08	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar

Publications (1)

Publication Number	Publication Date
ZA888558B true ZA888558B (en)	1989-08-30

Family

ID=8148726

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA888558A ZA888558B (en)	1987-12-08	1988-11-16	Imidazoquinoxaline compounds,their preparations and use

Country Status (18)

Country	Link
US (2)	US4968682A (fr)
EP (1)	EP0320136B1 (fr)
JP (1)	JPH01190684A (fr)
KR (1)	KR0133079B1 (fr)
AT (1)	ATE109147T1 (fr)
AU (1)	AU613125B2 (fr)
CA (1)	CA1327797C (fr)
DE (1)	DE3850861T2 (fr)
DK (1)	DK160876C (fr)
ES (1)	ES2056941T3 (fr)
FI (2)	FI90548C (fr)
IE (1)	IE66336B1 (fr)
IL (1)	IL88313A (fr)
NO (1)	NO169540C (fr)
NZ (1)	NZ227212A (fr)
PH (1)	PH24818A (fr)
PT (1)	PT89170B (fr)
ZA (1)	ZA888558B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
IL90315A0 (en) *	1988-06-01	1989-12-15	Ferrosan As	Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them
DK626288D0 (da) *	1988-11-10	1988-11-10	Ferrosan As	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
US5602252A (en) *	1989-11-17	1997-02-11	Berlex Laboratories, Inc.	Tricyclic pteridinones and a process for their preparation
US5854419A (en) *	1989-11-17	1998-12-29	Schering Aktiengesellschaft	Tricyclic pteridinones and a process for their preparation
DK588489D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
US5276028A (en) *	1990-06-22	1994-01-04	Nordisk A/S	Imidazoquinoxaline compounds
US5371080A (en) *	1990-06-22	1994-12-06	Novo Nordisk A/S	Imidazoquinazoline compounds and their use
DK151890D0 (da) *	1990-06-22	1990-06-22	Ferrosan As	Heterocykliske forbindelser deres fremstilling og brug
KR100207360B1 (ko) *	1991-06-14	1999-07-15	돈 더블유. 슈미츠	이미다조[1,5,-a]퀸옥살린
JPH0525037A (ja) *	1991-07-01	1993-02-02	Upjohn Co:The	経口投与酵素感受性腸溶製剤
WO1993016082A1 (fr) *	1992-02-13	1993-08-19	The Upjohn Company	Benzoxazines 4-oxo et 4h-imidazo(5,1-c)(1,4) utiles comme agents de liaison de recepteurs de benzodiazepine
TW274550B (fr) *	1992-09-26	1996-04-21	Hoechst Ag
EP0743855A1 (fr) *	1994-01-03	1996-11-27	Acea Pharmaceuticals, Inc.	8-aza, 6-aza et 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones et leur utilisation comme antagonistes du recepteur de la glycine ou du nmda
US5792766A (en)	1996-03-13	1998-08-11	Neurogen Corporation	Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
EP1978966A4 (fr)	2006-01-23	2010-11-10	Amira Pharmaceuticals Inc	Inhibiteurs tricycliques de la 5-lipoxygenase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4440929A (en) *	1981-07-16	1984-04-03	Usv Pharmaceutical Corporation	Imidazoquinoxaline compounds
JPS5823693A (ja) *	1981-07-16	1983-02-12	ユ−エスヴイ−・フア−マシユ−テイカル・コ−ポレ−シヨン	イミダゾキノキザリン化合物類
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK161148C (da) *	1988-06-14	1991-11-18	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne

1987
- 1987-12-08 DK DK642287A patent/DK160876C/da not_active IP Right Cessation
1988
- 1988-11-07 IL IL88313A patent/IL88313A/xx not_active IP Right Cessation
- 1988-11-07 IE IE334788A patent/IE66336B1/en not_active IP Right Cessation
- 1988-11-11 PH PH37802A patent/PH24818A/en unknown
- 1988-11-16 ZA ZA888558A patent/ZA888558B/xx unknown
- 1988-11-21 DE DE3850861T patent/DE3850861T2/de not_active Expired - Fee Related
- 1988-11-21 AT AT88310982T patent/ATE109147T1/de not_active IP Right Cessation
- 1988-11-21 EP EP88310982A patent/EP0320136B1/fr not_active Expired - Lifetime
- 1988-11-21 ES ES88310982T patent/ES2056941T3/es not_active Expired - Lifetime
- 1988-11-28 FI FI885518A patent/FI90548C/fi not_active IP Right Cessation
- 1988-11-30 CA CA000584610A patent/CA1327797C/fr not_active Expired - Fee Related
- 1988-12-06 PT PT89170A patent/PT89170B/pt not_active IP Right Cessation
- 1988-12-06 AU AU26602/88A patent/AU613125B2/en not_active Ceased
- 1988-12-06 NZ NZ227212A patent/NZ227212A/xx unknown
- 1988-12-06 KR KR1019880016202A patent/KR0133079B1/ko not_active Expired - Fee Related
- 1988-12-07 US US07/281,090 patent/US4968682A/en not_active Expired - Fee Related
- 1988-12-07 NO NO885442A patent/NO169540C/no unknown
- 1988-12-08 JP JP63308994A patent/JPH01190684A/ja active Pending
1990
- 1990-01-03 US US07/460,310 patent/US4999354A/en not_active Expired - Fee Related
1992
- 1992-11-23 FI FI925309A patent/FI93836C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK160876C (da)	1991-10-14
FI925309A0 (fi)	1992-11-23
PH24818A (en)	1990-10-30
CA1327797C (fr)	1994-03-15
NO169540B (no)	1992-03-30
FI885518A0 (fi)	1988-11-28
IE66336B1 (en)	1995-12-27
IE883347L (en)	1989-06-08
FI93836B (fi)	1995-02-28
PT89170B (pt)	1993-06-30
AU2660288A (en)	1989-06-08
ATE109147T1 (de)	1994-08-15
IL88313A (en)	1993-06-10
US4999354A (en)	1991-03-12
FI90548C (fi)	1994-02-25
NO885442D0 (no)	1988-12-07
FI925309L (fi)	1992-11-23
EP0320136A3 (en)	1990-12-19
DK642287A (da)	1989-06-09
NO885442L (no)	1989-06-09
US4968682A (en)	1990-11-06
ES2056941T3 (es)	1994-10-16
PT89170A (pt)	1989-12-29
FI885518A7 (fi)	1989-06-09
NZ227212A (en)	1990-07-26
DK642287D0 (da)	1987-12-08
KR0133079B1 (ko)	1998-04-17
DE3850861D1 (de)	1994-09-01
FI90548B (fi)	1993-11-15
DK160876B (da)	1991-04-29
EP0320136A2 (fr)	1989-06-14
NO169540C (no)	1992-07-08
DE3850861T2 (de)	1994-11-10
JPH01190684A (ja)	1989-07-31
IL88313A0 (en)	1989-06-30
EP0320136B1 (fr)	1994-07-27
FI93836C (fi)	1995-06-12
KR890009931A (ko)	1989-08-04
AU613125B2 (en)	1991-07-25

Publication	Publication Date	Title
ZA888558B (en)	1989-08-30	Imidazoquinoxaline compounds,their preparations and use
NO892456L (no)	1989-12-15	Fremgangsmaate for fremstilling av imidazokinoxalinforbindelser.
PH25034A (en)	1991-01-28	Process for the preparation of imidazoquinazoline compounds and intermediate for use in said process
EP0311321A3 (en)	1990-08-01	Heterocyclic compounds and their preparation and use