ZA8944B - K+ channel activator/beta-blocker compositions - Google Patents

K+ channel activator/beta-blocker compositions

Info

Publication number
ZA8944B
ZA8944B ZA8944A ZA8944A ZA8944B ZA 8944 B ZA8944 B ZA 8944B ZA 8944 A ZA8944 A ZA 8944A ZA 8944 A ZA8944 A ZA 8944A ZA 8944 B ZA8944 B ZA 8944B
Authority
ZA
South Africa
Prior art keywords
beta
channel activator
blocker
blocker compositions
compositions
Prior art date
Application number
ZA8944A
Other languages
English (en)
Inventor
John Morris Evans
Morris Evans John
Robin Edwin Buckingham
Edwin Buckingham Robin
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10629550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA8944(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA8944B publication Critical patent/ZA8944B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA8944A 1988-01-06 1989-01-04 K+ channel activator/beta-blocker compositions ZA8944B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888800199A GB8800199D0 (en) 1988-01-06 1988-01-06 Pharmaceutical preparation

Publications (1)

Publication Number Publication Date
ZA8944B true ZA8944B (en) 1990-09-26

Family

ID=10629550

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8944A ZA8944B (en) 1988-01-06 1989-01-04 K+ channel activator/beta-blocker compositions

Country Status (15)

Country Link
US (1) US5032591A (fr)
EP (1) EP0323745B1 (fr)
JP (1) JPH01224316A (fr)
KR (1) KR890011591A (fr)
AT (1) ATE83375T1 (fr)
AU (1) AU614008B2 (fr)
CA (1) CA1317228C (fr)
DE (1) DE3876773T2 (fr)
DK (1) DK2689A (fr)
ES (1) ES2042776T3 (fr)
GB (1) GB8800199D0 (fr)
GR (1) GR3006857T3 (fr)
NZ (1) NZ227518A (fr)
PT (1) PT89388B (fr)
ZA (1) ZA8944B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2071668T3 (es) * 1988-12-13 1995-07-01 Beecham Group Plc Benzopirano y compuestos relacionados.
FR2645021A1 (fr) * 1989-03-30 1990-10-05 Sanofi Sa Utilisation d'un agoniste potassique dans le traitement du glaucome
FR2653662B1 (fr) * 1989-10-31 1994-05-13 Rhone Poulenc Sante Application du n-methyl (pyridyl-3)-2 tetrahydrothiopyranne-carbothioamide-2-oxyde-1 a la preparation de medicaments destines au traitement de l'insuffisance coronarienne.
FR2657872B2 (fr) * 1989-11-06 1992-06-12 Sanofi Sa Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
TW224941B (fr) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
DE4004268A1 (de) * 1990-02-13 1991-08-14 Merck Patent Gmbh Pharmazeutische zubereitung
CA2089261A1 (fr) * 1990-08-30 1992-03-01 John F.W. Keana Amidines substituees a fort pouvoir liant avec le recepteur sigma
US5643921A (en) * 1990-09-26 1997-07-01 E.R. Squibb & Sons, Inc. Cardiopulmonary bypass and organ transplant using a potassium channel activator
GB9124754D0 (en) * 1991-11-21 1992-01-15 Smithkline Beecham Plc Pharmaceuticals
GB9807779D0 (en) 1998-04-09 1998-06-10 Ciba Geigy Ag Organic compounds
US6417207B1 (en) * 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
US7799832B2 (en) * 2003-10-23 2010-09-21 Valeant Pharmaceuticals North America Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
CA2589363A1 (fr) * 2004-12-13 2006-06-22 Eli Lilly And Company Derives spiro utilises en tant qu'inhibiteurs de lipoxygenase
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
NZ575652A (en) * 2006-08-23 2011-08-26 Valeant Pharmaceuticals Int Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
KR20090083479A (ko) * 2006-11-28 2009-08-03 밸리언트 파마슈티컬즈 인터내셔널 칼륨 채널 조절제로서의 1,4 디아미노 이환 레티가빈 유사체
US20080207073A1 (en) * 2007-02-22 2008-08-28 David Michael Jones Coated multi-purpose fabric
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
CA3155812A1 (fr) 2019-11-08 2021-05-14 Cynthia Louise HARDEN Methodes de traitement de troubles depressifs
TW202245744A (zh) 2021-02-09 2022-12-01 加拿大商再諾製藥公司 治療失樂症之方法及用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
EP0093535B1 (fr) * 1982-04-28 1986-12-30 Beecham Group Plc Chromènes et chromanes
EP0095316B1 (fr) * 1982-05-21 1986-12-03 Beecham Group Plc Aminobenzopyrannes pharmaceutiquement actifs
DE3364734D1 (en) * 1982-10-19 1986-08-28 Beecham Group Plc Novel chromans and chromenes
GB8308063D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8313679D0 (en) * 1983-05-18 1983-06-22 Beecham Group Plc Active compounds
EP0126311B1 (fr) * 1983-05-18 1989-09-13 Beecham Group Plc Dérivés de benzopyrane.
DE3486354T2 (de) * 1983-05-18 1995-03-30 Beecham Group Plc Chroman- und Chromenderivate.
DE3475786D1 (de) * 1983-09-01 1989-02-02 Beecham Group Plc Chromanol derivatives
DE3477779D1 (en) * 1983-10-13 1989-05-24 Beecham Group Plc Chroman derivatives
GB8419515D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8513369D0 (en) * 1985-05-28 1985-07-03 Beecham Group Plc Treatment
EP0205292B1 (fr) * 1985-06-08 1991-11-06 Beecham Group Plc Dérivés de pyrano[3,2-c] pyridine, procédé et intermédiaires pour leur préparation et compositions pharmaceutiques les contenant
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
GB8613786D0 (en) * 1986-06-06 1986-07-09 Beecham Group Plc Active compounds
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
ATE71535T1 (de) * 1986-12-06 1992-02-15 Beecham Group Plc Pharmazeutische zubereitungen.
DE3726261A1 (de) * 1986-12-23 1988-07-07 Merck Patent Gmbh Chromanderivate
ES2058148T3 (es) * 1987-02-04 1994-11-01 Hoechst Ag N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen

Also Published As

Publication number Publication date
DE3876773D1 (de) 1993-01-28
ES2042776T3 (es) 1993-12-16
EP0323745A2 (fr) 1989-07-12
DK2689D0 (da) 1989-01-04
US5032591A (en) 1991-07-16
EP0323745B1 (fr) 1992-12-16
CA1317228C (fr) 1993-05-04
EP0323745A3 (en) 1990-03-21
GR3006857T3 (fr) 1993-06-30
ATE83375T1 (de) 1993-01-15
AU2769689A (en) 1989-07-06
PT89388B (pt) 1993-09-30
PT89388A (pt) 1990-02-08
KR890011591A (ko) 1989-08-21
DE3876773T2 (de) 1993-04-29
DK2689A (da) 1989-07-07
AU614008B2 (en) 1991-08-15
JPH01224316A (ja) 1989-09-07
GB8800199D0 (en) 1988-02-10
NZ227518A (en) 1991-08-27

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