ZA894560B - Process for preparing 1-(p-tert-butylphenyl)-4(4'-(alpha hydroxy-diphenylmethyl)-1'-pyperidinyl)butanol - Google Patents
Process for preparing 1-(p-tert-butylphenyl)-4(4'-(alpha hydroxy-diphenylmethyl)-1'-pyperidinyl)butanolInfo
- Publication number
- ZA894560B ZA894560B ZA894560A ZA894560A ZA894560B ZA 894560 B ZA894560 B ZA 894560B ZA 894560 A ZA894560 A ZA 894560A ZA 894560 A ZA894560 A ZA 894560A ZA 894560 B ZA894560 B ZA 894560B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyperidinyl
- diphenylmethyl
- butylphenyl
- butanol
- tert
- Prior art date
Links
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21003/88A IT1217837B (it) | 1988-06-17 | 1988-06-17 | Procedimento per la preparazione del "alfa /4(1,1 dimetiletil)fenil/piperidinbutanolo" |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA894560B true ZA894560B (en) | 1990-05-30 |
Family
ID=11175262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA894560A ZA894560B (en) | 1988-06-17 | 1989-06-15 | Process for preparing 1-(p-tert-butylphenyl)-4(4'-(alpha hydroxy-diphenylmethyl)-1'-pyperidinyl)butanol |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0346765A3 (fr) |
| JP (1) | JPH0245467A (fr) |
| KR (1) | KR900000350A (fr) |
| CA (1) | CA1309101C (fr) |
| DK (1) | DK287289A (fr) |
| HU (1) | HU205072B (fr) |
| IL (1) | IL90616A0 (fr) |
| IT (1) | IT1217837B (fr) |
| ZA (1) | ZA894560B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA903145B (en) * | 1989-05-01 | 1991-02-27 | Merrell Dow Pharma | Process for the preparation of the high melting polymorphic form of terfenadine |
| FR2681861B1 (fr) * | 1991-10-01 | 1995-06-09 | Isochem Sa | Procede de preparation d'une forme polymorphique de la terfenadine, a point de fusion eleve, d'une plus grande purete et produit obtenu. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4742175A (en) * | 1986-05-07 | 1988-05-03 | Merrell Dow Pharmaceuticals Inc. | Preparation of polymorphically pure terfenadine |
-
1988
- 1988-06-17 IT IT21003/88A patent/IT1217837B/it active
-
1989
- 1989-06-08 EP EP19890110377 patent/EP0346765A3/fr not_active Withdrawn
- 1989-06-13 DK DK287289A patent/DK287289A/da not_active Application Discontinuation
- 1989-06-14 IL IL90616A patent/IL90616A0/xx unknown
- 1989-06-15 JP JP1150665A patent/JPH0245467A/ja active Pending
- 1989-06-15 ZA ZA894560A patent/ZA894560B/xx unknown
- 1989-06-16 KR KR1019890008317A patent/KR900000350A/ko not_active Withdrawn
- 1989-06-16 CA CA000602993A patent/CA1309101C/fr not_active Expired - Lifetime
- 1989-06-16 HU HU893123A patent/HU205072B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0245467A (ja) | 1990-02-15 |
| DK287289A (da) | 1989-12-18 |
| IT1217837B (it) | 1990-03-30 |
| DK287289D0 (da) | 1989-06-13 |
| IL90616A0 (en) | 1990-01-18 |
| EP0346765A2 (fr) | 1989-12-20 |
| KR900000350A (ko) | 1990-01-30 |
| HU205072B (en) | 1992-03-30 |
| CA1309101C (fr) | 1992-10-20 |
| EP0346765A3 (fr) | 1990-10-17 |
| IT8821003A0 (it) | 1988-06-17 |
| HUT50770A (en) | 1990-03-28 |
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