ZA896374B - Neuropeptide y antagonists - Google Patents

Neuropeptide y antagonists

Info

Publication number
ZA896374B
ZA896374B ZA896374A ZA896374A ZA896374B ZA 896374 B ZA896374 B ZA 896374B ZA 896374 A ZA896374 A ZA 896374A ZA 896374 A ZA896374 A ZA 896374A ZA 896374 B ZA896374 B ZA 896374B
Authority
ZA
South Africa
Prior art keywords
neuropeptide
antagonists
npy
derivatives
antagonism
Prior art date
Application number
ZA896374A
Other languages
English (en)
Inventor
John Leonard Krstenansky
Leonard Krstenansky John
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA896374B publication Critical patent/ZA896374B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57545—Neuropeptide Y
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA896374A 1988-08-26 1989-08-21 Neuropeptide y antagonists ZA896374B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23759988A 1988-08-26 1988-08-26

Publications (1)

Publication Number Publication Date
ZA896374B true ZA896374B (en) 1990-05-30

Family

ID=22894403

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA896374A ZA896374B (en) 1988-08-26 1989-08-21 Neuropeptide y antagonists

Country Status (15)

Country Link
EP (1) EP0355794B1 (fr)
JP (1) JPH02111793A (fr)
KR (1) KR900003203A (fr)
CN (1) CN1040594A (fr)
AT (1) ATE100466T1 (fr)
DE (1) DE68912453T2 (fr)
DK (1) DK421489A (fr)
ES (1) ES2061839T3 (fr)
FI (1) FI894007L (fr)
HU (1) HU204541B (fr)
IL (1) IL91396A0 (fr)
NO (1) NO893431L (fr)
NZ (1) NZ230385A (fr)
PT (1) PT91539B (fr)
ZA (1) ZA896374B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69229283T2 (de) * 1991-11-06 1999-09-23 Garvan Institute Of Medical Research, Darlinghurst Humaner neuropeptid y-y1 rezeptor
GB9213215D0 (en) * 1992-06-20 1992-08-05 Wellcome Found Peptides
US5516653A (en) * 1993-12-28 1996-05-14 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) 1994-02-03 1996-08-13 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
US5989920A (en) * 1994-12-02 1999-11-23 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US5602024A (en) 1994-12-02 1997-02-11 Synaptic Pharmaceutical Corporation DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
US6713265B1 (en) 1997-06-04 2004-03-30 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
WO2004098591A2 (fr) 2003-05-05 2004-11-18 Probiodrug Ag Inhibiteurs de glutaminyl-cyclase
AU2004290499C1 (en) 2003-11-03 2011-02-24 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
CA2554809C (fr) 2004-02-05 2014-04-29 Probiodrug Ag Nouveaux inhibiteurs de la glutaminyl-cyclase comportant de la n thiouree alkyle et de l'imidazolyl substitue par thioamide
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
EP2142514B1 (fr) 2007-04-18 2014-12-24 Probiodrug AG Dérivés de thio-urée utilisés comme inhibiteurs de la glutaminyl cyclase
EP2264026A4 (fr) 2008-03-06 2012-03-28 Msd Kk Dérivé d'alkylaminopyridine
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
NZ602312A (en) 2010-03-10 2014-02-28 Probiodrug Ag Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
WO2011131748A2 (fr) 2010-04-21 2011-10-27 Probiodrug Ag Nouveaux inhibiteurs
EP2686313B1 (fr) 2011-03-16 2016-02-03 Probiodrug AG Dérivés de benzimidazole en tant qu'inhibiteurs de la glutaminyl cyclase
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa

Also Published As

Publication number Publication date
FI894007A7 (fi) 1990-02-27
PT91539B (pt) 1995-05-04
DK421489D0 (da) 1989-08-25
KR900003203A (ko) 1990-03-26
ES2061839T3 (es) 1994-12-16
EP0355794A2 (fr) 1990-02-28
HU204541B (en) 1992-01-28
FI894007A0 (fi) 1989-08-25
EP0355794A3 (fr) 1991-01-23
PT91539A (pt) 1990-03-08
DK421489A (da) 1990-02-27
EP0355794B1 (fr) 1994-01-19
CN1040594A (zh) 1990-03-21
HUT50486A (en) 1990-02-28
JPH02111793A (ja) 1990-04-24
NZ230385A (en) 1992-04-28
ATE100466T1 (de) 1994-02-15
DE68912453T2 (de) 1994-05-11
IL91396A0 (en) 1990-04-29
AU4017689A (en) 1990-03-01
NO893431D0 (no) 1989-08-25
FI894007L (fi) 1990-02-27
NO893431L (no) 1990-02-27
AU620432B2 (en) 1992-02-20
DE68912453D1 (de) 1994-03-03

Similar Documents

Publication Publication Date Title
ZA896374B (en) Neuropeptide y antagonists
ZA896376B (en) Neuropeptide y agonists
DK163373C (da) Afspaerringsarmatur i form af en kuglehaneventil
DE69219205D1 (de) Von Hand führbares Bohrgerät
DK538985D0 (da) Basiske v1-vasopressin-antagonister
GB2198284B (en) Determining the composition of a solid body
YU47889A (en) Concrete suspension with manganese oxide content for cementing oil drills
DE68925335D1 (de) Harzzusammensetzung und ihre Verwendung
GB2154491B (en) Wood turning tool rest
USD294064S (en) Wooden roofing tile
DE69505351D1 (de) Zyklische neurokinin a - antagonisten
EP0373545A3 (en) Competitive genadoliberin antagonists
AU620432C (en) Neuropeptide Y antagonists
IE892747L (en) Neuropeptide y antagonists
KR900012985U (ko) 다용도게시판용 이동구
IT8840048A0 (it) Attrezzo ginnico polivalente
IT8748341A0 (it) Endodiatermia a punta d'oro
KR890000450U (ko) 수동드릴의 작업대
GB8405447D0 (en) Collapsible table construction
GB8605100D0 (en) Taper fit cue extension
SE8801085D0 (sv) Spolarstoppen
AU96396S (en) Timber sink
PHUM7229Z (en) Marbleized wood cement board