ZA897633B - Recombinant pdgf and methods for production - Google Patents

Recombinant pdgf and methods for production

Info

Publication number
ZA897633B
ZA897633B ZA897633A ZA897633A ZA897633B ZA 897633 B ZA897633 B ZA 897633B ZA 897633 A ZA897633 A ZA 897633A ZA 897633 A ZA897633 A ZA 897633A ZA 897633 B ZA897633 B ZA 897633B
Authority
ZA
South Africa
Prior art keywords
production
methods
recombinant pdgf
pdgf
recombinant
Prior art date
Application number
ZA897633A
Other languages
English (en)
Inventor
Charles Tackney
Tackney Charles
Jurgen Hoppe
Hoppe Jurgen
Wolfram Eichner
Eichner Wolfram
Herbert Weich
Weich Herbert
Original Assignee
Tackney Charles
Hoppe Jurgen
Eichner Wolfram
Weich Herbert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tackney Charles, Hoppe Jurgen, Eichner Wolfram, Weich Herbert filed Critical Tackney Charles
Publication of ZA897633B publication Critical patent/ZA897633B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA897633A 1988-10-06 1989-10-06 Recombinant pdgf and methods for production ZA897633B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3834079A DE3834079A1 (de) 1988-10-06 1988-10-06 Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren

Publications (1)

Publication Number Publication Date
ZA897633B true ZA897633B (en) 1991-07-31

Family

ID=6364549

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897633A ZA897633B (en) 1988-10-06 1989-10-06 Recombinant pdgf and methods for production

Country Status (7)

Country Link
US (1) US5334532A (fr)
EP (1) EP0437544A4 (fr)
AU (1) AU4508689A (fr)
CA (1) CA2000309A1 (fr)
DE (1) DE3834079A1 (fr)
WO (1) WO1990004035A1 (fr)
ZA (1) ZA897633B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759815A (en) * 1988-02-11 1998-06-02 Creative Biomolecules, Inc. Production of platelet derived growth factor (PDGF) an muteins thereof
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
US5272064A (en) * 1989-12-19 1993-12-21 Amgen Inc. DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof
ES2055611T3 (es) * 1990-07-23 1994-08-16 Zymogenetics Inc Pdgf resistente a proteasas y metodos de uso.
EP0495638A3 (en) * 1991-01-16 1993-06-02 Schering Corporation Expression of mature pdgf-b in escherichia coli
US5763584A (en) * 1992-05-18 1998-06-09 Genentech, Inc. Receptor activation with hepatocyte growth factor agonists
WO1993023550A2 (fr) * 1992-05-18 1993-11-25 Genentech, Inc. Activation de recepteurs d'oligomerisation grace a des ligands de recepteurs fusionnes
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
US5955430A (en) * 1993-09-24 1999-09-21 University Of Southern California Use of angiotensin II fragments and analogs thereof in tissue repair
US7144991B2 (en) 1999-06-07 2006-12-05 Aletheon Pharmaceuticals, Inc. Streptavidin expressed gene fusions and methods of use thereof
US20030143233A1 (en) * 1999-06-07 2003-07-31 Neorx Corporation Streptavidin expressed gene fusions and methods of use thereof
US20030103948A1 (en) * 1999-06-07 2003-06-05 Neorx Corporation Streptavidin expressed gene fusions and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738921A (en) * 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
US4769328A (en) * 1984-10-12 1988-09-06 Zymogenetics Inc. Expression of biologically active PDGF analogs in yeast
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4889919A (en) * 1986-08-13 1989-12-26 Zymogenetics, Inc. Biologically active PDGF derived A-chain homodimers
US4751180A (en) * 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product

Also Published As

Publication number Publication date
WO1990004035A1 (fr) 1990-04-19
EP0437544A1 (fr) 1991-07-24
CA2000309A1 (fr) 1990-04-06
DE3834079A1 (de) 1990-04-12
EP0437544A4 (en) 1991-11-06
US5334532A (en) 1994-08-02
AU4508689A (en) 1990-05-01

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