ZA897821B - Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number: ZA897821B
Authority: ZA; South Africa
Prior art keywords: image; amino; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1988-10-17

Application number

ZA897821A

Other languages

English (en)

Inventor

Gilbert Regnier

Regnier Gilbert

Alain Dhainaut

Dhainaut Alain

Jean-Paul Vilaine

Vilaine Jean-Paul

Nicole Villeneuve

Villeneuve Nicole

Ghislaine Joly

Joly Ghislaine

Jacques Duhault

Duhault Jacques

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-17

Filing date

1989-10-16

Publication date

1990-07-25

1989-10-16 Application filed by Adir filed Critical Adir

1990-07-25 Publication of ZA897821B publication Critical patent/ZA897821B/xx

Links

XPKQHJJKXONCHR-UHFFFAOYSA-N 2-amino-3,4-dihydrochromen-2-ol Chemical class C1=CC=C2OC(N)(O)CCC2=C1 XPKQHJJKXONCHR-UHFFFAOYSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 2
125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
102000004257 Potassium Channel Human genes 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000004913 activation Effects 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
125000004656 alkyl sulfonylamino group Chemical group 0.000 abstract 1
125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000004472 dialkylaminosulfonyl group Chemical group 0.000 abstract 1
230000001079 digestive effect Effects 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000002526 effect on cardiovascular system Effects 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
108020001213 potassium channel Proteins 0.000 abstract 1
HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical class O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
230000016160 smooth muscle contraction Effects 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
230000002485 urinary effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Peptides Or Proteins (AREA)

ZA897821A 1988-10-17 1989-10-16 Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them ZA897821B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8813637A FR2637896B1 (fr)	1988-10-17	1988-10-17	Nouveaux derives de l'amino chromanol, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number	Publication Date
ZA897821B true ZA897821B (en)	1990-07-25

Family

ID=9371088

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA897821A ZA897821B (en)	1988-10-17	1989-10-16	Amino-chromanol derivatives,process for the preparation thereof and pharmaceutical compositions containing them

Country Status (15)

Country	Link
US (1)	US4999372A (de)
EP (1)	EP0365416B1 (de)
JP (1)	JPH068296B2 (de)
AT (1)	ATE94543T1 (de)
AU (1)	AU620157B2 (de)
CA (1)	CA2000743A1 (de)
DE (1)	DE68909167T2 (de)
DK (1)	DK492089A (de)
ES (1)	ES2059802T3 (de)
FR (1)	FR2637896B1 (de)
IE (1)	IE64369B1 (de)
NZ (1)	NZ231029A (de)
OA (1)	OA09430A (de)
PT (1)	PT92007B (de)
ZA (1)	ZA897821B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1216461B (it) *	1988-02-26	1990-03-08	Milano	Derivati del 1_aril solfonil2_pirrolidinone loro procedimentodi preparazione e loro impieto come medicinali.
IT1244881B (it) *	1990-12-13	1994-09-12	Roussel Pharma Spa	Derivati dell'1-arilsolfonil 2-pirrolidone, loro procedimento di preparazione e i nuovi intermedi cosi' ottenuti ,il loro impiego come farmaci e le composizioni farmaceutiche che li contengono

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1495526A (en) *	1974-05-31	1977-12-21	Beecham Group Ltd	Chroman derivatives
EP0172352B1 (de) *	1984-06-22	1990-08-29	Beecham Group Plc	Wirksame Benzopyranverbindungen
GB8625185D0 (en) *	1986-10-21	1986-11-26	Beecham Group Plc	Active compounds
ES2058148T3 (es) *	1987-02-04	1994-11-01	Hoechst Ag	N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.

1988
- 1988-10-17 FR FR8813637A patent/FR2637896B1/fr not_active Expired - Lifetime
1989
- 1989-10-05 DK DK492089A patent/DK492089A/da not_active Application Discontinuation
- 1989-10-11 US US07/419,824 patent/US4999372A/en not_active Expired - Fee Related
- 1989-10-16 IE IE331889A patent/IE64369B1/en not_active IP Right Cessation
- 1989-10-16 NZ NZ231029A patent/NZ231029A/xx unknown
- 1989-10-16 PT PT92007A patent/PT92007B/pt not_active IP Right Cessation
- 1989-10-16 CA CA002000743A patent/CA2000743A1/fr not_active Abandoned
- 1989-10-16 AU AU42872/89A patent/AU620157B2/en not_active Ceased
- 1989-10-16 ZA ZA897821A patent/ZA897821B/xx unknown
- 1989-10-17 AT AT89402857T patent/ATE94543T1/de not_active IP Right Cessation
- 1989-10-17 ES ES89402857T patent/ES2059802T3/es not_active Expired - Lifetime
- 1989-10-17 DE DE89402857T patent/DE68909167T2/de not_active Expired - Fee Related
- 1989-10-17 EP EP89402857A patent/EP0365416B1/de not_active Expired - Lifetime
- 1989-10-17 JP JP1270154A patent/JPH068296B2/ja not_active Expired - Lifetime
- 1989-10-17 OA OA59664A patent/OA09430A/xx unknown

Also Published As

Publication number	Publication date
DE68909167T2 (de)	1994-04-14
DK492089A (da)	1990-04-18
EP0365416A1 (de)	1990-04-25
IE893318L (en)	1990-04-17
EP0365416B1 (de)	1993-09-15
US4999372A (en)	1991-03-12
PT92007B (pt)	1995-06-30
JPH02149578A (ja)	1990-06-08
FR2637896A1 (fr)	1990-04-20
CA2000743A1 (fr)	1990-04-17
PT92007A (pt)	1990-04-30
DE68909167D1 (de)	1993-10-21
JPH068296B2 (ja)	1994-02-02
AU4287289A (en)	1990-04-26
ES2059802T3 (es)	1994-11-16
IE64369B1 (en)	1995-07-26
NZ231029A (en)	1990-10-26
ATE94543T1 (de)	1993-10-15
OA09430A (fr)	1992-10-15
AU620157B2 (en)	1992-02-13
FR2637896B1 (fr)	1990-11-30
DK492089D0 (da)	1989-10-05

Publication	Publication Date	Title
AU588185B2 (en)	1989-09-07	Vinylphenol derivatives, their preparation and their use
GR3025742T3 (en)	1998-03-31	New pyrazine derivatives, their preparation and their use.
IE892340L (en)	1990-01-20	4-oxoquinoline-3-carboxylic acid derivatives, their¹preparation and their use
NZ243443A (en)	1995-01-27	Triazolopyrimidine derivatives, preparation and pharmaceutical compositions thereof
DE3566545D1 (en)	1989-01-05	2-substituted-1,3-propylidenediphosphonate derivatives, the process for their preparation and pharmaceutical compositions containing them
AU551811B2 (en)	1986-05-15	Imidazodiazepines
GB9108629D0 (en)	1991-06-12	Heterocyclic pharmaceutical compounds,preparation and use
AU4287289A (en)	1990-04-26	New aminochromanol derivatives, process for the preparation thereof and pharmaceutical compositions containing them
AU572612B2 (en)	1988-05-12	Isoxazole derivatives
AU5455780A (en)	1980-07-24	Hexahydro-1,4-oxazepines
AU2994589A (en)	1989-08-24	Novel basic-substituted 5-halo-thienoisothiazol-3-(2h)-one-1,1-dioxides, process for the preparation thereof, and pharmaceutical preparations containing these compounds
DE3160044D1 (en)	1983-03-17	2,3-dihydroimidazo (1,2-b) pyridazine derivatives, process for their preparation and their therapeutical use
PH24258A (en)	1990-05-04	Substituted quinoxyalyl-imidazolidine-2,4-diones,their use as medicaments and pharmaceutical preparation
HU901631D0 (en)	1990-06-28	Process for the preparation of thienyl-piperazine derivatives and pharmaceutical compositions containing them