ZA897886B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA897886B ZA897886B ZA897886A ZA897886A ZA897886B ZA 897886 B ZA897886 B ZA 897886B ZA 897886 A ZA897886 A ZA 897886A ZA 897886 A ZA897886 A ZA 897886A ZA 897886 B ZA897886 B ZA 897886B
- Authority
- ZA
- South Africa
- Prior art keywords
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888824400A GB8824400D0 (en) | 1988-10-18 | 1988-10-18 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897886B true ZA897886B (en) | 1990-09-26 |
Family
ID=10645389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897886A ZA897886B (en) | 1988-10-18 | 1989-10-18 | Heterocyclic compounds |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5109008A (fr) |
| EP (1) | EP0366327A1 (fr) |
| JP (1) | JPH02191278A (fr) |
| KR (1) | KR900006341A (fr) |
| AU (1) | AU629585B2 (fr) |
| CA (1) | CA2000894A1 (fr) |
| DK (1) | DK517989A (fr) |
| FI (1) | FI894960A7 (fr) |
| GB (1) | GB8824400D0 (fr) |
| NZ (1) | NZ231056A (fr) |
| PT (1) | PT92010A (fr) |
| ZA (1) | ZA897886B (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| US5322848A (en) * | 1989-11-24 | 1994-06-21 | Dr. Lo Zembeletti S.P.A. | N-acyl-substituted azacyclic compounds, processes for their preparation, and their use as pharmaceuticals |
| GB8926560D0 (en) * | 1989-11-24 | 1990-01-17 | Zambeletti Spa L | Pharmaceuticals |
| US5428042A (en) * | 1990-04-28 | 1995-06-27 | Dr Lo Zambeletti S.P.A. | 1-(2H-1-oxo-3,4-dihydronaphtyl-6-yl)-acetyl-piperidines as kappa agonists |
| US5122088A (en) * | 1991-01-28 | 1992-06-16 | Meline Ralph E | Mute for an elk call |
| GB9104839D0 (en) * | 1991-03-07 | 1991-04-17 | Zambeletti Spa L | Novel compounds |
| ES2124318T3 (es) * | 1992-07-28 | 1999-02-01 | Merck Sharp & Dohme | Compuestos azaciclicos. |
| DE4328228A1 (de) * | 1993-08-23 | 1995-03-02 | Basf Ag | Verfahren zur Herstellung von Pyrazol und dessen Derivaten |
| IT1273751B (it) * | 1994-02-11 | 1997-07-10 | Smithkline Beecham Farma | Derivati azaciclici |
| US5688955A (en) * | 1996-03-08 | 1997-11-18 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6303611B1 (en) | 1996-03-08 | 2001-10-16 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US5763445A (en) * | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| USRE38133E1 (en) * | 1996-03-08 | 2003-06-03 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6750216B2 (en) | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| CA2288828A1 (fr) * | 1997-07-14 | 1999-01-28 | Adolor Corporation | Compositions pharmaceutiques anti-pruritiques contenant des agonistes de recepteurs kappa et procede de traitement du prurit a l'aide desdites compositions |
| US5760023A (en) * | 1997-07-14 | 1998-06-02 | Adolor Corporation | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith |
| KR100295740B1 (ko) | 1998-09-17 | 2001-11-05 | 박영구 | N-치환된-하이드록시고리화알킬아민유도체의제조방법 |
| KR100939347B1 (ko) | 2005-07-20 | 2010-01-29 | (주)카이로드 | 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법 |
| US8445700B2 (en) | 2008-11-24 | 2013-05-21 | Council Of Scientific & Industrial Research | Process for the preparation of optically active N-benzyl-3 hydroxypyrrolidines |
| SG10201510665WA (en) | 2009-12-04 | 2016-01-28 | Sunovion Pharmaceuticals Inc | Multicycle Compounds And Pharmaceutical Compositions Useful For The Treatment Of Neurological Disorders |
| PT3494119T (pt) | 2016-07-29 | 2024-12-10 | Pgi Drug Discovery Llc | Compostos e composições e seus usos |
| MA45795A (fr) | 2016-07-29 | 2019-06-05 | Sunovion Pharmaceuticals Inc | Composés et compositions, et utilisations associées |
| MX390141B (es) | 2017-02-16 | 2025-03-20 | Sunovion Pharmaceuticals Inc | Metodos para tratar esquizofrenia |
| CA3070993C (fr) | 2017-08-02 | 2025-05-20 | Sunovion Pharmaceuticals Inc. | Composés d’isochromane et leurs utilisations |
| UA130249C2 (uk) | 2018-02-16 | 2025-12-31 | Сумітомо Фарма Америка, Інк. | Солі, кристалічні форми і способи їх отримання |
| EP3938045A1 (fr) | 2019-03-14 | 2022-01-19 | Sunovion Pharmaceuticals Inc. | Sels d'un composé d'isochromanyle et formes cristallines, procédés de préparation, utilisations thérapeutiques et compositions pharmaceutiques associées |
| CA3180115A1 (fr) | 2020-04-14 | 2021-10-21 | Sunovion Pharmaceuticals Inc. | (s)-(4,5-dihydro-7 h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine pour le traitement de troubles neurologiques et psychiatriques |
| EP4382529A1 (fr) | 2022-12-07 | 2024-06-12 | Bayer Consumer Care AG | Procédé de préparation de (3s)-pyrrolidin-3-ol pur et de chlorhydrate de (3s)-pyrrolidin-3-ol pur |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3903095A (en) * | 1972-02-18 | 1975-09-02 | Merck & Co Inc | Certain substituted-thieno{8 3,2-c{9 -pyridines |
| US3845065A (en) * | 1972-02-18 | 1974-10-29 | Merck & Co Inc | 4-oxo-4,5-dihydrothieno(3,2-c)pyridines |
| FR2215948B1 (fr) * | 1973-02-01 | 1976-05-14 | Centre Etd Ind Pharma | |
| FR2395028A2 (fr) * | 1977-06-22 | 1979-01-19 | Centre Etd Ind Pharma | Derives pyridiniques, leur preparation et leurs application therapeutique |
| US4579863A (en) * | 1983-12-06 | 1986-04-01 | Warner-Lambert Company | Substituted trans-1,2-diaminocyclohexyl amide compounds |
| US4618621A (en) * | 1984-09-21 | 1986-10-21 | The Upjohn Company | Method for treating medical conditions involving cerebral ischemia |
| GB8531615D0 (en) * | 1985-12-23 | 1986-02-05 | Zambeletti Spa L | Compounds |
| FR2592879B1 (fr) * | 1986-01-13 | 1988-04-29 | Roussel Uclaf | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| EP0260041B1 (fr) * | 1986-09-02 | 1991-01-30 | Dr. Lo. Zambeletti S.p.A. | Dérivés de la pipéridine substitués en position 1 par un groupement acyle |
| US4731368A (en) * | 1986-12-08 | 1988-03-15 | Merck & Co., Inc. | Thienopyridine sulfonamides and their ophthalmological formulation |
| EP0271273A3 (fr) * | 1986-12-08 | 1989-07-12 | Merck & Co. Inc. | Thiéno et furopyridine sulfonamides |
| PT86427B (pt) * | 1986-12-22 | 1990-11-20 | Zambeletti Spa L | Processo para a preparacao de derivados de piperidina |
| FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| ES2075849T3 (es) * | 1988-03-16 | 1995-10-16 | Smithkline Beecham Farma | Derivados heterociclicos. |
-
1988
- 1988-10-18 GB GB888824400A patent/GB8824400D0/en active Pending
-
1989
- 1989-10-16 EP EP89310616A patent/EP0366327A1/fr not_active Ceased
- 1989-10-17 PT PT92010A patent/PT92010A/pt unknown
- 1989-10-17 CA CA002000894A patent/CA2000894A1/fr not_active Abandoned
- 1989-10-17 KR KR1019890014918A patent/KR900006341A/ko not_active Withdrawn
- 1989-10-18 AU AU42948/89A patent/AU629585B2/en not_active Ceased
- 1989-10-18 ZA ZA897886A patent/ZA897886B/xx unknown
- 1989-10-18 NZ NZ231056A patent/NZ231056A/en unknown
- 1989-10-18 FI FI894960A patent/FI894960A7/fi not_active IP Right Cessation
- 1989-10-18 JP JP1269267A patent/JPH02191278A/ja active Pending
- 1989-10-18 US US07/423,202 patent/US5109008A/en not_active Expired - Fee Related
- 1989-10-18 DK DK517989A patent/DK517989A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2000894A1 (fr) | 1990-04-18 |
| KR900006341A (ko) | 1990-05-08 |
| NZ231056A (en) | 1992-02-25 |
| DK517989A (da) | 1990-04-19 |
| DK517989D0 (da) | 1989-10-18 |
| AU629585B2 (en) | 1992-10-08 |
| FI894960A0 (fi) | 1989-10-18 |
| JPH02191278A (ja) | 1990-07-27 |
| PT92010A (pt) | 1990-04-30 |
| GB8824400D0 (en) | 1988-11-23 |
| US5109008A (en) | 1992-04-28 |
| AU4294889A (en) | 1990-04-26 |
| FI894960A7 (fi) | 1990-04-19 |
| EP0366327A1 (fr) | 1990-05-02 |
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