ZA897886B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
ZA897886B
ZA897886B ZA897886A ZA897886A ZA897886B ZA 897886 B ZA897886 B ZA 897886B ZA 897886 A ZA897886 A ZA 897886A ZA 897886 A ZA897886 A ZA 897886A ZA 897886 B ZA897886 B ZA 897886B
Authority
ZA
South Africa
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
ZA897886A
Other languages
English (en)
Inventor
David Ian Carter Scopes
Ian Carter Scopes David
Duncan Bruce Judd
Bruce Judd Duncan
David John Belton
John Belton David
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA897886B publication Critical patent/ZA897886B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA897886A 1988-10-18 1989-10-18 Heterocyclic compounds ZA897886B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888824400A GB8824400D0 (en) 1988-10-18 1988-10-18 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA897886B true ZA897886B (en) 1990-09-26

Family

ID=10645389

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897886A ZA897886B (en) 1988-10-18 1989-10-18 Heterocyclic compounds

Country Status (12)

Country Link
US (1) US5109008A (fr)
EP (1) EP0366327A1 (fr)
JP (1) JPH02191278A (fr)
KR (1) KR900006341A (fr)
AU (1) AU629585B2 (fr)
CA (1) CA2000894A1 (fr)
DK (1) DK517989A (fr)
FI (1) FI894960A7 (fr)
GB (1) GB8824400D0 (fr)
NZ (1) NZ231056A (fr)
PT (1) PT92010A (fr)
ZA (1) ZA897886B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
US5322848A (en) * 1989-11-24 1994-06-21 Dr. Lo Zembeletti S.P.A. N-acyl-substituted azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
GB8926560D0 (en) * 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
US5428042A (en) * 1990-04-28 1995-06-27 Dr Lo Zambeletti S.P.A. 1-(2H-1-oxo-3,4-dihydronaphtyl-6-yl)-acetyl-piperidines as kappa agonists
US5122088A (en) * 1991-01-28 1992-06-16 Meline Ralph E Mute for an elk call
GB9104839D0 (en) * 1991-03-07 1991-04-17 Zambeletti Spa L Novel compounds
ES2124318T3 (es) * 1992-07-28 1999-02-01 Merck Sharp & Dohme Compuestos azaciclicos.
DE4328228A1 (de) * 1993-08-23 1995-03-02 Basf Ag Verfahren zur Herstellung von Pyrazol und dessen Derivaten
IT1273751B (it) * 1994-02-11 1997-07-10 Smithkline Beecham Farma Derivati azaciclici
US5688955A (en) * 1996-03-08 1997-11-18 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6303611B1 (en) 1996-03-08 2001-10-16 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6239154B1 (en) 1996-03-08 2001-05-29 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
US5763445A (en) * 1996-03-08 1998-06-09 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
USRE38133E1 (en) * 1996-03-08 2003-06-03 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6750216B2 (en) 1996-03-08 2004-06-15 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6057323A (en) * 1996-03-08 2000-05-02 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
CA2288828A1 (fr) * 1997-07-14 1999-01-28 Adolor Corporation Compositions pharmaceutiques anti-pruritiques contenant des agonistes de recepteurs kappa et procede de traitement du prurit a l'aide desdites compositions
US5760023A (en) * 1997-07-14 1998-06-02 Adolor Corporation Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith
KR100295740B1 (ko) 1998-09-17 2001-11-05 박영구 N-치환된-하이드록시고리화알킬아민유도체의제조방법
KR100939347B1 (ko) 2005-07-20 2010-01-29 (주)카이로드 광학적으로 순수한 (s)-3-히드록시 피롤리딘의 제조방법
US8445700B2 (en) 2008-11-24 2013-05-21 Council Of Scientific & Industrial Research Process for the preparation of optically active N-benzyl-3 hydroxypyrrolidines
SG10201510665WA (en) 2009-12-04 2016-01-28 Sunovion Pharmaceuticals Inc Multicycle Compounds And Pharmaceutical Compositions Useful For The Treatment Of Neurological Disorders
PT3494119T (pt) 2016-07-29 2024-12-10 Pgi Drug Discovery Llc Compostos e composições e seus usos
MA45795A (fr) 2016-07-29 2019-06-05 Sunovion Pharmaceuticals Inc Composés et compositions, et utilisations associées
MX390141B (es) 2017-02-16 2025-03-20 Sunovion Pharmaceuticals Inc Metodos para tratar esquizofrenia
CA3070993C (fr) 2017-08-02 2025-05-20 Sunovion Pharmaceuticals Inc. Composés d’isochromane et leurs utilisations
UA130249C2 (uk) 2018-02-16 2025-12-31 Сумітомо Фарма Америка, Інк. Солі, кристалічні форми і способи їх отримання
EP3938045A1 (fr) 2019-03-14 2022-01-19 Sunovion Pharmaceuticals Inc. Sels d'un composé d'isochromanyle et formes cristallines, procédés de préparation, utilisations thérapeutiques et compositions pharmaceutiques associées
CA3180115A1 (fr) 2020-04-14 2021-10-21 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7 h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine pour le traitement de troubles neurologiques et psychiatriques
EP4382529A1 (fr) 2022-12-07 2024-06-12 Bayer Consumer Care AG Procédé de préparation de (3s)-pyrrolidin-3-ol pur et de chlorhydrate de (3s)-pyrrolidin-3-ol pur

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3845065A (en) * 1972-02-18 1974-10-29 Merck & Co Inc 4-oxo-4,5-dihydrothieno(3,2-c)pyridines
FR2215948B1 (fr) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
FR2395028A2 (fr) * 1977-06-22 1979-01-19 Centre Etd Ind Pharma Derives pyridiniques, leur preparation et leurs application therapeutique
US4579863A (en) * 1983-12-06 1986-04-01 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
US4618621A (en) * 1984-09-21 1986-10-21 The Upjohn Company Method for treating medical conditions involving cerebral ischemia
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
FR2592879B1 (fr) * 1986-01-13 1988-04-29 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
EP0260041B1 (fr) * 1986-09-02 1991-01-30 Dr. Lo. Zambeletti S.p.A. Dérivés de la pipéridine substitués en position 1 par un groupement acyle
US4731368A (en) * 1986-12-08 1988-03-15 Merck & Co., Inc. Thienopyridine sulfonamides and their ophthalmological formulation
EP0271273A3 (fr) * 1986-12-08 1989-07-12 Merck & Co. Inc. Thiéno et furopyridine sulfonamides
PT86427B (pt) * 1986-12-22 1990-11-20 Zambeletti Spa L Processo para a preparacao de derivados de piperidina
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
DE68910999T2 (de) * 1988-02-19 1994-03-24 Smithkline Beecham Farma 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten.
ES2075849T3 (es) * 1988-03-16 1995-10-16 Smithkline Beecham Farma Derivados heterociclicos.

Also Published As

Publication number Publication date
CA2000894A1 (fr) 1990-04-18
KR900006341A (ko) 1990-05-08
NZ231056A (en) 1992-02-25
DK517989A (da) 1990-04-19
DK517989D0 (da) 1989-10-18
AU629585B2 (en) 1992-10-08
FI894960A0 (fi) 1989-10-18
JPH02191278A (ja) 1990-07-27
PT92010A (pt) 1990-04-30
GB8824400D0 (en) 1988-11-23
US5109008A (en) 1992-04-28
AU4294889A (en) 1990-04-26
FI894960A7 (fi) 1990-04-19
EP0366327A1 (fr) 1990-05-02

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