ZA908936B - Treatment of multi-drug resistant tumors with quinolyloxazole-2-ones - Google Patents

Treatment of multi-drug resistant tumors with quinolyloxazole-2-ones

Info

Publication number: ZA908936B
Authority: ZA; South Africa
Prior art keywords: quinolyloxazole; ones; treatment; resistant tumors; drug resistant
Prior art date: 1989-11-13

Application number

ZA908936A

Other languages

English (en)

Inventor

Sai Prasad Sunkara

Prasad Sunkara Sai

Winton Dennis Jones

Dennis Jones Winton

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-13

Filing date

1990-11-07

Publication date

1991-09-25

1990-11-07 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1991-09-25 Publication of ZA908936B publication Critical patent/ZA908936B/xx

Links

206010028980 Neoplasm Diseases 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
206010059866 Drug resistance Diseases 0.000 abstract 2
239000002246 antineoplastic agent Substances 0.000 abstract 1
229940127089 cytotoxic agent Drugs 0.000 abstract 1
210000004881 tumor cell Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA908936A 1989-11-13 1990-11-07 Treatment of multi-drug resistant tumors with quinolyloxazole-2-ones ZA908936B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43626289A	1989-11-13	1989-11-13

Publications (1)

Publication Number	Publication Date
ZA908936B true ZA908936B (en)	1991-09-25

Family

ID=23731760

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA908936A ZA908936B (en)	1989-11-13	1990-11-07	Treatment of multi-drug resistant tumors with quinolyloxazole-2-ones

Country Status (10)

Country	Link
EP (1)	EP0428107B1 (fr)
JP (1)	JP2927931B2 (fr)
KR (1)	KR0168645B1 (fr)
AT (1)	ATE100319T1 (fr)
AU (1)	AU629423B2 (fr)
DE (1)	DE69006188T2 (fr)
DK (1)	DK0428107T3 (fr)
ES (1)	ES2062267T3 (fr)
IE (1)	IE63850B1 (fr)
ZA (1)	ZA908936B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5863977A (en) *	1993-10-12	1999-01-26	H. B. Fuller Licensing & Financing, Inc.	High molecular weight S-EB-S hot melt adhesive
GB9819382D0 (en)	1998-09-04	1998-10-28	Cerebrus Ltd	Chemical compounds I
US6693099B2 (en)	2000-10-17	2004-02-17	The Procter & Gamble Company	Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en)	2000-10-17	2002-04-23	The Procter & Gamble Co.	Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3827974A1 (de) *	1988-08-18	1990-02-22	Boehringer Mannheim Gmbh	Kombinationspraeparate von proteinkinase-c-inhibitoren mit lipiden, lipid-analoga, cytostatica oder inhibitoren von phospholipasen
US4886811A (en) *	1988-10-24	1989-12-12	Merrell Dow Pharmaceuticals	Qunolyloxazole-2-ones useful as proteinkinase C inhibitors

1990
- 1990-11-07 ZA ZA908936A patent/ZA908936B/xx unknown
- 1990-11-08 AU AU65928/90A patent/AU629423B2/en not_active Ceased
- 1990-11-12 ES ES90121634T patent/ES2062267T3/es not_active Expired - Lifetime
- 1990-11-12 IE IE407790A patent/IE63850B1/en not_active IP Right Cessation
- 1990-11-12 DK DK90121634.1T patent/DK0428107T3/da active
- 1990-11-12 DE DE69006188T patent/DE69006188T2/de not_active Expired - Fee Related
- 1990-11-12 KR KR1019900018248A patent/KR0168645B1/ko not_active Expired - Fee Related
- 1990-11-12 EP EP90121634A patent/EP0428107B1/fr not_active Expired - Lifetime
- 1990-11-12 AT AT90121634T patent/ATE100319T1/de not_active IP Right Cessation
- 1990-11-13 JP JP2304166A patent/JP2927931B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0428107A2 (fr)	1991-05-22
IE63850B1 (en)	1995-06-14
ES2062267T3 (es)	1994-12-16
ATE100319T1 (de)	1994-02-15
JP2927931B2 (ja)	1999-07-28
DK0428107T3 (da)	1994-02-28
KR910009261A (ko)	1991-06-28
DE69006188D1 (de)	1994-03-03
AU6592890A (en)	1991-05-16
JPH03170429A (ja)	1991-07-24
AU629423B2 (en)	1992-10-01
KR0168645B1 (ko)	1999-01-15
DE69006188T2 (de)	1994-05-26
EP0428107B1 (fr)	1994-01-19
IE904077A1 (en)	1991-05-22
EP0428107A3 (en)	1991-12-11

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