ZA909042B - Deoxfluoronucleoside process - Google Patents

Deoxfluoronucleoside process

Info

Publication number
ZA909042B
ZA909042B ZA909042A ZA909042A ZA909042B ZA 909042 B ZA909042 B ZA 909042B ZA 909042 A ZA909042 A ZA 909042A ZA 909042 A ZA909042 A ZA 909042A ZA 909042 B ZA909042 B ZA 909042B
Authority
ZA
South Africa
Prior art keywords
deoxfluoronucleoside
deoxfluoronucleoside process
Prior art date
Application number
ZA909042A
Other languages
English (en)
Inventor
Purushotham Vemishetti
Vemishetti Purushotham
Henry G Howell
G Howell Henry
Donald G Walker
G Walker Donald
Paul R Brodfuehrer
R Brodfuehrer Paul
Kun-Mao Shih
Shih Kun-Mao
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ZA909042B publication Critical patent/ZA909042B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA909042A 1989-11-13 1990-11-12 Deoxfluoronucleoside process ZA909042B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43585289A 1989-11-13 1989-11-13

Publications (1)

Publication Number Publication Date
ZA909042B true ZA909042B (en) 1991-09-25

Family

ID=23730082

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909042A ZA909042B (en) 1989-11-13 1990-11-12 Deoxfluoronucleoside process

Country Status (12)

Country Link
EP (1) EP0428109A3 (fr)
JP (1) JPH03170496A (fr)
KR (1) KR910009717A (fr)
AU (1) AU6596590A (fr)
CA (1) CA2029301A1 (fr)
FI (1) FI905536A7 (fr)
HU (4) HU906976D0 (fr)
IE (1) IE904070A1 (fr)
IL (1) IL96306A0 (fr)
NO (1) NO174206C (fr)
PT (1) PT95861A (fr)
ZA (1) ZA909042B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401838A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
SG94686A1 (en) * 1992-06-22 2003-03-18 Lilly Co Eli Stereoselective gylcosylation process
AU659009B2 (en) * 1992-06-22 1995-05-04 Eli Lilly And Company Stereoselective glycosylation process
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5821357A (en) * 1992-06-22 1998-10-13 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5606048A (en) * 1992-06-22 1997-02-25 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
CZ123493A3 (en) * 1992-06-22 1994-02-16 Lilly Co Eli Stereoselective anionic glycosylation process
UA41261C2 (uk) * 1992-06-22 2001-09-17 Елі Ліллі Енд Компані Спосіб одержання збагачених бета-аномером нуклеозидів
US5371210A (en) * 1992-06-22 1994-12-06 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) * 1992-06-22 1997-01-14 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
AU659008B2 (en) * 1992-06-22 1995-05-04 Eli Lilly And Company Stereoselective anion glycosylation process
US5424416A (en) * 1993-08-25 1995-06-13 Eli Lilly And Company Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
AT400953B (de) * 1994-08-25 1996-05-28 Joern Saischek Pentofuranosid-derivate, deren herstellung und verwendung
JPH11217396A (ja) * 1998-01-30 1999-08-10 Ajinomoto Co Inc ヌクレオシド誘導体の製造方法
AU3851601A (en) * 2000-02-18 2001-08-27 Southern Res Inst Methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h- purin-6-amine
US6680382B2 (en) 2001-08-02 2004-01-20 Ilex Products, Inc. Process for preparing purine nucleosides
TWI635093B (zh) 2011-05-19 2018-09-11 基利科學股份有限公司 用於製備抗ｈｉｖ藥劑的方法與中間物
SI3661937T1 (sl) 2017-08-01 2021-11-30 Gilead Sciences, Inc. Kristalinične oblike etil((S)-((((2R,5R)-5-(6-amino-9H-purin-9-IL)-4- fluoro-2,5-dihidrofuran-2-IL)oksi)metil)(fenoksi)fosforil)-L-alaninata (GS-9131) za zdravljenje virusnih okužb

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
CA1340645C (fr) * 1987-04-17 1999-07-13 Victor E. Marquez Didesoxynucleosides stables en milieu acide, actifs contre les effets cytopathiques du virus de l'immunoeficience humaine
EP0314011A3 (fr) * 1987-10-30 1990-04-11 F. Hoffmann-La Roche Ag Dérivés de la purine
GB8816345D0 (en) * 1988-07-08 1988-08-10 Hoffmann La Roche Purine derivatives

Also Published As

Publication number Publication date
FI905536A7 (fi) 1991-05-14
EP0428109A2 (fr) 1991-05-22
NO904870L (no) 1991-05-14
JPH03170496A (ja) 1991-07-24
CA2029301A1 (fr) 1991-05-14
AU6596590A (en) 1991-05-16
HU208149B (en) 1993-08-30
NO904870D0 (no) 1990-11-09
HU9303049D0 (en) 1994-01-28
EP0428109A3 (en) 1991-09-11
KR910009717A (ko) 1991-06-28
HUT57790A (en) 1991-12-30
FI905536A0 (fi) 1990-11-08
NO174206B (no) 1993-12-20
HU9303048D0 (en) 1994-01-28
HU907113D0 (en) 1991-05-28
HU906976D0 (en) 1991-05-28
IL96306A0 (en) 1991-08-16
NO174206C (no) 1994-04-06
IE904070A1 (en) 1991-05-22
PT95861A (pt) 1991-09-13

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