ZA913430B - Muteins of the granulocyte colony stimulating factor - Google Patents

Muteins of the granulocyte colony stimulating factor

Info

Publication number
ZA913430B
ZA913430B ZA913430A ZA913430A ZA913430B ZA 913430 B ZA913430 B ZA 913430B ZA 913430 A ZA913430 A ZA 913430A ZA 913430 A ZA913430 A ZA 913430A ZA 913430 B ZA913430 B ZA 913430B
Authority
ZA
South Africa
Prior art keywords
muteins
stimulating factor
colony stimulating
granulocyte colony
granulocyte
Prior art date
Application number
ZA913430A
Other languages
English (en)
Inventor
Guenther Schumacher
Schumacher Guenther
Carola Dony
Dony Carola
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA913430B publication Critical patent/ZA913430B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00—Working by laser beam, e.g. welding, cutting or boring
    • B23K26/351—Working by laser beam, e.g. welding, cutting or boring for trimming or tuning of electrical components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA913430A 1990-05-08 1991-05-07 Muteins of the granulocyte colony stimulating factor ZA913430B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014750A DE4014750A1 (de) 1990-05-08 1990-05-08 Muteine des granulozyten-stimulierenden faktors (g-csf)

Publications (1)

Publication Number Publication Date
ZA913430B true ZA913430B (en) 1992-02-26

Family

ID=6405959

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913430A ZA913430B (en) 1990-05-08 1991-05-07 Muteins of the granulocyte colony stimulating factor

Country Status (17)

Country Link
EP (1) EP0456200A1 (cs)
JP (1) JPH04225998A (cs)
KR (1) KR940000757B1 (cs)
CN (1) CN1057862A (cs)
AU (1) AU631312B2 (cs)
CA (1) CA2041439A1 (cs)
CS (1) CS133391A3 (cs)
DE (1) DE4014750A1 (cs)
FI (1) FI912203L (cs)
HU (1) HUT58801A (cs)
IE (1) IE911359A1 (cs)
IL (1) IL98070A0 (cs)
NO (1) NO911786L (cs)
NZ (1) NZ237975A (cs)
PL (1) PL290166A1 (cs)
PT (1) PT97611A (cs)
ZA (1) ZA913430B (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718893A (en) * 1984-04-15 1998-02-17 Foster; Preston F. Use of G-CSF to reduce acute rejection
GB9107846D0 (en) * 1990-04-30 1991-05-29 Ici Plc Polypeptides
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5536495A (en) * 1994-04-15 1996-07-16 Foster; Preston F. Use of G-CSF to reduce acute rejection
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
KR100440460B1 (ko) * 1998-07-08 2004-10-08 주식회사유한양행 인체 과립구 콜로니 자극인자의 유전자, 재조합 벡터 및 형질 전환체 및 그들을 이용한 인체 과립구 콜로니 자극인자의 제조방법
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
DE19860801A1 (de) * 1998-12-30 2000-07-06 Rhein Biotech Proz & Prod Gmbh Rekombinanter Wachstumsfaktor mit der biologischen Aktivität eines G-CSF (Granulocyte Colony Stimulating Factor)
AU2001290846B2 (en) * 2000-09-08 2006-02-02 Massachusetts Institute Of Technology G-CSF analog compositions and methods
AU2002256624B2 (en) 2001-02-19 2007-12-06 Merck Patent Gmbh Method for identification of T-cell epitopes and use for preparing molecules with reduced immunogenicity
ATE468862T1 (de) 2001-07-11 2010-06-15 Maxygen Inc G-csf konjugate
US20040247562A1 (en) * 2001-09-28 2004-12-09 Sang Yup Lee Diagnostic method for cancer characterized in the detection of the deletion of g-csf exon 3
US7785601B2 (en) 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7695723B2 (en) 2002-12-31 2010-04-13 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
DE102004041639A1 (de) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
ATE544463T1 (de) 2004-11-05 2012-02-15 Univ Northwestern Verwendung von scf und g-scf bei der behandlung von hirnischämie und neurologischen störungen
US7381805B2 (en) 2005-06-01 2008-06-03 Maxygen Holdings, Ltd. Compositions comprising mixtures of positional PEG isomers of PEGylated G-CSF
DE102005033250A1 (de) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
DE202006020194U1 (de) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
EP2581441A1 (en) 2007-08-09 2013-04-17 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
PT2076243E (pt) 2007-08-27 2014-12-05 Ratiopharm Gmbh Formulação líquida de g-csf
DE202007018629U1 (de) 2007-08-27 2008-12-24 Biogenerix Ag Flüssigformulierung von G-CSF
DK2197919T3 (da) 2007-08-27 2014-07-07 Ratiopharm Gmbh Flydende formulering af g-csf-konjugat
WO2009046015A2 (en) 2007-09-30 2009-04-09 University Of Florida Research Foundation, Inc. Combination therapies for treating type 1 diabetes
WO2011109556A2 (en) 2010-03-04 2011-09-09 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturing
AU2011235210B2 (en) 2010-04-01 2015-07-16 Pfenex Inc. Methods for G-CSF production in a Pseudomonas host cell
EP2399572A1 (en) 2010-06-22 2011-12-28 Sandoz AG Long-term storage of non-glycosylated recombinant human G-CSF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102021B2 (ja) * 1985-12-03 1994-12-14 中外製薬株式会社 新規なポリペプチド
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするｄｎａ
JPH01500483A (ja) * 1986-08-11 1989-02-23 シタス　コーポレイション Ｇ‐ｃｓｆ及びそのミューテインの発現
WO1988003173A2 (en) * 1986-10-24 1988-05-05 Cetus Corporation New forms of colony stimulating factor-1
NO176799C (no) * 1986-12-23 1995-05-31 Kyowa Hakko Kogyo Kk DNA som koder for et polypeptid, rekombinant plasmid som koder for og kan uttrykke et polypeptid og fremgangsmåte for fremstilling av dette polypeptid

Also Published As

Publication number Publication date
IL98070A0 (en) 1992-06-21
FI912203A7 (fi) 1991-11-09
NZ237975A (en) 1992-09-25
KR910020033A (ko) 1991-12-19
IE911359A1 (en) 1991-11-20
JPH04225998A (ja) 1992-08-14
PT97611A (pt) 1992-03-31
EP0456200A1 (de) 1991-11-13
HU911529D0 (en) 1991-11-28
AU7638091A (en) 1991-11-14
PL290166A1 (en) 1992-01-13
CS133391A3 (en) 1992-01-15
HUT58801A (en) 1992-03-30
AU631312B2 (en) 1992-11-19
KR940000757B1 (ko) 1994-01-29
FI912203A0 (fi) 1991-05-07
FI912203L (fi) 1991-11-09
CN1057862A (zh) 1992-01-15
DE4014750A1 (de) 1991-11-14
NO911786L (no) 1991-11-11
CA2041439A1 (en) 1991-11-09
NO911786D0 (no) 1991-05-07

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