ZA913963B - Process for the preparation of 10-(2-propynyl)estr-4-ene-3,17-dione - Google Patents
Process for the preparation of 10-(2-propynyl)estr-4-ene-3,17-dioneInfo
- Publication number
- ZA913963B ZA913963B ZA913963A ZA913963A ZA913963B ZA 913963 B ZA913963 B ZA 913963B ZA 913963 A ZA913963 A ZA 913963A ZA 913963 A ZA913963 A ZA 913963A ZA 913963 B ZA913963 B ZA 913963B
- Authority
- ZA
- South Africa
- Prior art keywords
- dione
- ene
- propynyl
- estr
- preparation
- Prior art date
Links
- JKPDEYAOCSQBSZ-OEUJLIAZSA-N plomestane Chemical compound O=C1CC[C@]2(CC#C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 JKPDEYAOCSQBSZ-OEUJLIAZSA-N 0.000 title abstract 2
- RORYLAUXKSWMQL-CBZIJGRNSA-N (8r,9s,13s,14s)-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione Chemical compound C1CC(=O)CC2=C1[C@H]1CC[C@](C)(C(CC3)=O)[C@@H]3[C@@H]1CC2 RORYLAUXKSWMQL-CBZIJGRNSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002568 propynyl group Chemical group [*]C#CC([H])([H])[H] 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- -1 steroid epoxides Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53067490A | 1990-05-30 | 1990-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA913963B true ZA913963B (en) | 1992-04-29 |
Family
ID=24114524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA913963A ZA913963B (en) | 1990-05-30 | 1991-05-24 | Process for the preparation of 10-(2-propynyl)estr-4-ene-3,17-dione |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0459381B1 (fr) |
| JP (1) | JP2989935B2 (fr) |
| KR (1) | KR0171410B1 (fr) |
| AT (1) | ATE150465T1 (fr) |
| AU (1) | AU649251B2 (fr) |
| DE (1) | DE69125207T2 (fr) |
| DK (1) | DK0459381T3 (fr) |
| ES (1) | ES2101702T3 (fr) |
| GR (1) | GR3023380T3 (fr) |
| HU (1) | HU212575B (fr) |
| IE (1) | IE911834A1 (fr) |
| IL (1) | IL98384A (fr) |
| ZA (1) | ZA913963B (fr) |
-
1991
- 1991-05-24 AU AU77290/91A patent/AU649251B2/en not_active Ceased
- 1991-05-24 ZA ZA913963A patent/ZA913963B/xx unknown
- 1991-05-28 KR KR1019910008696A patent/KR0171410B1/ko not_active Expired - Fee Related
- 1991-05-28 DK DK91108664.3T patent/DK0459381T3/da active
- 1991-05-28 ES ES91108664T patent/ES2101702T3/es not_active Expired - Lifetime
- 1991-05-28 EP EP91108664A patent/EP0459381B1/fr not_active Expired - Lifetime
- 1991-05-28 DE DE69125207T patent/DE69125207T2/de not_active Expired - Fee Related
- 1991-05-28 AT AT91108664T patent/ATE150465T1/de not_active IP Right Cessation
- 1991-05-29 IE IE183491A patent/IE911834A1/en unknown
- 1991-05-29 HU HU911800A patent/HU212575B/hu not_active IP Right Cessation
- 1991-05-30 JP JP3153686A patent/JP2989935B2/ja not_active Expired - Lifetime
- 1991-06-05 IL IL9838491A patent/IL98384A/en not_active IP Right Cessation
-
1997
- 1997-05-09 GR GR970401033T patent/GR3023380T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0459381T3 (da) | 1997-04-07 |
| DE69125207T2 (de) | 1997-06-26 |
| HUT57791A (en) | 1991-12-30 |
| DE69125207D1 (de) | 1997-04-24 |
| GR3023380T3 (en) | 1997-08-29 |
| JPH04235997A (ja) | 1992-08-25 |
| AU649251B2 (en) | 1994-05-19 |
| ATE150465T1 (de) | 1997-04-15 |
| IL98384A (en) | 1995-03-30 |
| IE911834A1 (en) | 1991-12-04 |
| EP0459381A3 (en) | 1992-06-10 |
| HU212575B (en) | 1996-08-29 |
| ES2101702T3 (es) | 1997-07-16 |
| JP2989935B2 (ja) | 1999-12-13 |
| EP0459381B1 (fr) | 1997-03-19 |
| KR0171410B1 (ko) | 1999-02-01 |
| EP0459381A2 (fr) | 1991-12-04 |
| AU7729091A (en) | 1991-12-05 |
| KR910020028A (ko) | 1991-12-19 |
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