ZA916340B - Carbamoyl-1-(pyridinylalkyl)-1h-indoles,indolines and related analogs - Google Patents
Carbamoyl-1-(pyridinylalkyl)-1h-indoles,indolines and related analogsInfo
- Publication number
- ZA916340B ZA916340B ZA916340A ZA916340A ZA916340B ZA 916340 B ZA916340 B ZA 916340B ZA 916340 A ZA916340 A ZA 916340A ZA 916340 A ZA916340 A ZA 916340A ZA 916340 B ZA916340 B ZA 916340B
- Authority
- ZA
- South Africa
- Prior art keywords
- loweralkyl
- hydrogen
- arylloweralkyl
- chem
- aryl
- Prior art date
Links
- 150000002476 indolines Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 150000002431 hydrogen Chemical class 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 3
- -1 arylloweralkyl Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56672490A | 1990-08-13 | 1990-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA916340B true ZA916340B (en) | 1992-04-29 |
Family
ID=24264113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA916340A ZA916340B (en) | 1990-08-13 | 1991-08-12 | Carbamoyl-1-(pyridinylalkyl)-1h-indoles,indolines and related analogs |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0471298B1 (cs) |
| JP (1) | JPH0670034B2 (cs) |
| KR (1) | KR100215156B1 (cs) |
| AT (1) | ATE129710T1 (cs) |
| AU (1) | AU638158B2 (cs) |
| CA (1) | CA2048931C (cs) |
| CZ (1) | CZ284753B6 (cs) |
| DE (1) | DE69114210T2 (cs) |
| DK (1) | DK0471298T3 (cs) |
| ES (1) | ES2079532T3 (cs) |
| FI (1) | FI104554B (cs) |
| GR (1) | GR3018068T3 (cs) |
| HU (1) | HUT58723A (cs) |
| IE (1) | IE69968B1 (cs) |
| IL (1) | IL99167A (cs) |
| MX (1) | MX9100640A (cs) |
| NO (1) | NO178372C (cs) |
| NZ (1) | NZ239327A (cs) |
| PT (1) | PT98646B (cs) |
| ZA (1) | ZA916340B (cs) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE787444A (fr) * | 1971-08-13 | 1973-02-12 | Hoffmann La Roche | Composes polycycliques |
| GB2102795A (en) * | 1981-07-31 | 1983-02-09 | Pfizer Ltd | Indole derivatives |
| FR2591595B1 (fr) * | 1985-12-13 | 1988-09-09 | Roussel Uclaf | Nouveaux derives du 4-morpholinyl 1h-indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et intermediaires |
| DE3809155A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | 1,3,4,5-tetrahydrobenz-(c,d)-indole |
| ATE130002T1 (de) * | 1990-08-13 | 1995-11-15 | Hoechst Roussel Pharma | 1-(pyridinylalkyl)-1h-indole, -indoline und analoge. |
-
1991
- 1991-08-08 AT AT91113336T patent/ATE129710T1/de not_active IP Right Cessation
- 1991-08-08 ES ES91113336T patent/ES2079532T3/es not_active Expired - Lifetime
- 1991-08-08 EP EP91113336A patent/EP0471298B1/en not_active Expired - Lifetime
- 1991-08-08 DE DE69114210T patent/DE69114210T2/de not_active Expired - Fee Related
- 1991-08-08 DK DK91113336.1T patent/DK0471298T3/da active
- 1991-08-09 NZ NZ23932791A patent/NZ239327A/en unknown
- 1991-08-09 FI FI913801A patent/FI104554B/fi not_active IP Right Cessation
- 1991-08-12 MX MX9100640A patent/MX9100640A/es not_active IP Right Cessation
- 1991-08-12 AU AU81766/91A patent/AU638158B2/en not_active Expired - Fee Related
- 1991-08-12 ZA ZA916340A patent/ZA916340B/xx unknown
- 1991-08-12 IL IL9916791A patent/IL99167A/en unknown
- 1991-08-12 KR KR1019910013848A patent/KR100215156B1/ko not_active Expired - Fee Related
- 1991-08-12 CA CA002048931A patent/CA2048931C/en not_active Expired - Fee Related
- 1991-08-12 JP JP3201712A patent/JPH0670034B2/ja not_active Expired - Lifetime
- 1991-08-12 NO NO913141A patent/NO178372C/no unknown
- 1991-08-12 PT PT98646A patent/PT98646B/pt not_active IP Right Cessation
- 1991-08-12 IE IE285291A patent/IE69968B1/en not_active IP Right Cessation
- 1991-08-12 HU HU912675A patent/HUT58723A/hu unknown
- 1991-08-12 CZ CS912490A patent/CZ284753B6/cs not_active IP Right Cessation
-
1995
- 1995-11-10 GR GR950403169T patent/GR3018068T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU8176691A (en) | 1992-02-20 |
| IE69968B1 (en) | 1996-10-16 |
| EP0471298B1 (en) | 1995-11-02 |
| KR100215156B1 (ko) | 1999-08-16 |
| HUT58723A (en) | 1992-03-30 |
| NO913141L (no) | 1992-02-14 |
| NO178372C (no) | 1996-03-13 |
| CS249091A3 (en) | 1992-03-18 |
| JPH05125075A (ja) | 1993-05-21 |
| DK0471298T3 (da) | 1996-03-04 |
| HU912675D0 (en) | 1992-01-28 |
| EP0471298A1 (en) | 1992-02-19 |
| PT98646A (pt) | 1992-06-30 |
| NZ239327A (en) | 1994-07-26 |
| ATE129710T1 (de) | 1995-11-15 |
| ES2079532T3 (es) | 1996-01-16 |
| IL99167A (en) | 1995-05-26 |
| IL99167A0 (en) | 1992-07-15 |
| CA2048931A1 (en) | 1992-02-14 |
| GR3018068T3 (en) | 1996-02-29 |
| CZ284753B6 (cs) | 1999-02-17 |
| PT98646B (pt) | 1999-01-29 |
| FI104554B (fi) | 2000-02-29 |
| DE69114210D1 (de) | 1995-12-07 |
| FI913801A0 (fi) | 1991-08-09 |
| NO913141D0 (no) | 1991-08-12 |
| DE69114210T2 (de) | 1996-05-02 |
| KR920004378A (ko) | 1992-03-27 |
| NO178372B (no) | 1995-12-04 |
| JPH0670034B2 (ja) | 1994-09-07 |
| FI913801A7 (fi) | 1992-02-14 |
| MX9100640A (es) | 1992-04-01 |
| CA2048931C (en) | 2001-10-30 |
| AU638158B2 (en) | 1993-06-17 |
| IE912852A1 (en) | 1992-02-26 |
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