ZA919731B - Low estrogen oral contraceptives - Google Patents

Low estrogen oral contraceptives

Info

Publication number: ZA919731B
Authority: ZA; South Africa
Prior art keywords: dosage units; equivalent; desogestrel; phase; progestogen
Prior art date: 1990-12-13

Application number

ZA919731A

Other languages

English (en)

Inventor

Engelbert Willem Bergink

Willem Bergink Engelbert

Original Assignee

Akzo Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-13

Filing date

1991-12-10

Publication date

1992-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8205195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA919731(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-12-10 Application filed by Akzo Nv filed Critical Akzo Nv

1992-09-30 Publication of ZA919731B publication Critical patent/ZA919731B/xx

Links

239000000262 estrogen Substances 0.000 title abstract 4
229940011871 estrogen Drugs 0.000 title abstract 4
229940127234 oral contraceptive Drugs 0.000 title 1
239000003539 oral contraceptive agent Substances 0.000 title 1
RPLCPCMSCLEKRS-BPIQYHPVSA-N desogestrel Chemical compound C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 RPLCPCMSCLEKRS-BPIQYHPVSA-N 0.000 abstract 4
229960004976 desogestrel Drugs 0.000 abstract 4
239000000583 progesterone congener Substances 0.000 abstract 4
239000003433 contraceptive agent Substances 0.000 abstract 2
BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 abstract 1
BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 abstract 1
230000002254 contraceptive effect Effects 0.000 abstract 1
230000001076 estrogenic effect Effects 0.000 abstract 1
229960002568 ethinylestradiol Drugs 0.000 abstract 1
230000000757 progestagenic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)
Steroid Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

ZA919731A 1990-12-13 1991-12-10 Low estrogen oral contraceptives ZA919731B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP90203309		1990-12-13

Publications (1)

Publication Number	Publication Date
ZA919731B true ZA919731B (en)	1992-09-30

Family

ID=8205195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA919731A ZA919731B (en)	1990-12-13	1991-12-10	Low estrogen oral contraceptives

Country Status (18)

Country	Link
US (1)	US5262408A (fr)
EP (1)	EP0491415B1 (fr)
JP (1)	JPH04290828A (fr)
KR (1)	KR100187316B1 (fr)
CN (1)	CN1036835C (fr)
AT (1)	ATE136218T1 (fr)
AU (1)	AU645382B2 (fr)
CA (1)	CA2057528C (fr)
DE (1)	DE69118493T2 (fr)
DK (1)	DK0491415T3 (fr)
ES (1)	ES2087964T3 (fr)
FI (1)	FI99083C (fr)
GR (1)	GR3020179T3 (fr)
IE (1)	IE71203B1 (fr)
NO (1)	NO179234C (fr)
NZ (1)	NZ240944A (fr)
PT (1)	PT99782B (fr)
ZA (1)	ZA919731B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5439913A (en) *	1992-05-12	1995-08-08	Schering Aktiengesellschaft	Contraception method using competitive progesterone antagonists and novel compounds useful therein
US5516769A (en) *	1993-02-19	1996-05-14	The Medical College Of Hampton Roads	Method of inhibiting fertilization
US6407082B1 (en)	1996-09-13	2002-06-18	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a vitamin D compound
DE4344462C2 (de)	1993-12-22	1996-02-01	Schering Ag	Zusammensetzung für die Empfängnisverhütung
DE4411585A1 (de) *	1994-03-30	1995-10-05	Schering Ag	Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption
US5552394A (en) *	1994-07-22	1996-09-03	The Medical College Of Hampton Roads	Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
IL115445A (en) *	1994-10-17	1999-08-17	Akzo Nobel Nv	Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
US5747480A (en) *	1996-05-08	1998-05-05	American Home Products Corporation	Oral contraceptive
WO1998004267A1 (fr) *	1996-07-26	1998-02-05	American Home Products Corporation	Contraceptif oral a base de progestine et d'oestrogene
US5888543A (en) *	1996-07-26	1999-03-30	American Home Products Corporation	Oral contraceptives
US6479475B1 (en)	1996-07-26	2002-11-12	Wyeth	Oral contraceptive
WO1998004269A1 (fr) *	1996-07-26	1998-02-05	American Home Products Corporation	Methode de contraception monophasique et kit comprenant une association de progestine et d'oestrogene
US6451778B1 (en)	1996-07-26	2002-09-17	Wyeth	Oral contraceptive
ES2229378T3 (es) *	1996-07-26	2005-04-16	Wyeth	Anticonceptivo oral.
US5858405A (en) *	1996-07-26	1999-01-12	American Home Products Corporation	Oral contraceptive
US6511970B1 (en)	1996-09-13	2003-01-28	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en)	2000-03-21	2004-07-20	Gustavo Rodriguez	Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6028064A (en)	1996-09-13	2000-02-22	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of progestin products
US6034074A (en)	1996-09-13	2000-03-07	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a Vitamin D compound
WO2001030355A1 (fr)	1999-10-25	2001-05-03	Laboratoire Theramex	Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation
FR2754179B1 (fr)	1996-10-08	1998-12-24	Theramex	Nouvelle composition hormononale et son utilisation
US6214815B1 (en) *	1998-12-23	2001-04-10	Ortho-Mcneil Pharmaceuticals, Inc.	Triphasic oral contraceptive
WO2001030356A1 (fr)	1999-10-25	2001-05-03	Laboratoire Theramex	Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
US6855703B1 (en)	2000-03-10	2005-02-15	Endeavor Pharmaceuticals	Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US6660726B2 (en)	2000-03-10	2003-12-09	Endeavor Pharmaceuticals	Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7459445B2 (en) *	2000-03-10	2008-12-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and topical pharmaceutical formulations of the same
US7989436B2 (en) *	2003-07-23	2011-08-02	Duramed Pharmaceuticals, Inc.	Estrogenic compounds and pharmaceutical formulations comprising the same
US20050113351A1 (en) *	2000-03-21	2005-05-26	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) *	2000-03-21	2004-09-09	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
MXPA04005445A (es)	2001-12-05	2005-03-23	Barr Lab Inc	Anticonceptivos orales para prevenir el embarazo y disminuir la sintomatologia premenstrual.
JP2005519962A (ja) *	2002-03-11	2005-07-07	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	スルファターゼを阻害する継続的プロゲストゲン避妊レジメン
TW200403075A (en) *	2002-05-29	2004-03-01	Akzo Nobel Nv	Progestagenic dosage units
JP2004140323A (ja) *	2002-08-20	2004-05-13	Sharp Corp	半導体レーザ装置およびその製造方法
US6992075B2 (en) *	2003-04-04	2006-01-31	Barr Laboratories, Inc.	C(14) estrogenic compounds
WO2004091535A2 (fr) *	2003-04-11	2004-10-28	Barr Laboratories, Inc.	Procede d'administration d'oestrogenes et de progestatifs
ES2340422T3 (es) *	2003-06-13	2010-06-02	Skendi Finance, Ltd.	Microparticulas constituidas por estradiol y colesterol.
NZ585546A (en) *	2003-07-16	2011-10-28	Teva Womens Health Inc	Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration
EP1535618A1 (fr) *	2003-11-26	2005-06-01	Schering Aktiengesellschaft	Préparation pharmaceutique pour le traitement hormonal continuel sur plus de 21-28 jours comprenant deux compositions d'estrogène et/ou de progestine
DE102004019743B4 (de) *	2004-04-20	2008-11-27	Bayer Schering Pharma Aktiengesellschaft	Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens
US20070111975A1 (en)	2004-10-07	2007-05-17	Duramed Pharmaceuticals, Inc.	Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens
MX2007004120A (es) *	2004-10-07	2007-06-15	Duramed Pharmaceuticals Inc	Metodos de tratamiento hormonal utilizando regimentes de ciclo prolongado de dosis ascendente.
US8153616B2 (en)	2005-10-17	2012-04-10	Bayer Pharma Aktiengesellschaft	Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same
EP1930010A1 (fr)	2006-10-20	2008-06-11	Bayer Schering Pharma Aktiengesellschaft	Utilisation de valvérate d'estradiol ou de 17ß-estradiol combiné à du dienogest pour traiter par voie orale la récupération et/ou l'augmentation de la libido féminine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2431704A1 (de) *	1974-07-02	1976-01-22	Asche Ag	Stufenkombinationspraeparate per kontrazeption
NL8001593A (nl) *	1980-03-18	1981-10-16	Akzo Nv	Meerfasisch combinatiepreparaat voor orale anticonceptie.
US4628051A (en) *	1983-09-26	1986-12-09	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4544554A (en) *	1983-09-26	1985-10-01	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
US4616006A (en) *	1983-09-26	1986-10-07	Ortho Pharmaceutical Corporation	Triphasic oral contraceptive
IE61236B1 (en) *	1986-07-15	1994-10-19	American Home Prod	Combination dosage form for pre-menopausal women

1991
- 1991-12-04 IE IE422191A patent/IE71203B1/en not_active IP Right Cessation
- 1991-12-05 AT AT91203182T patent/ATE136218T1/de not_active IP Right Cessation
- 1991-12-05 DE DE69118493T patent/DE69118493T2/de not_active Expired - Fee Related
- 1991-12-05 ES ES91203182T patent/ES2087964T3/es not_active Expired - Lifetime
- 1991-12-05 DK DK91203182.0T patent/DK0491415T3/da active
- 1991-12-05 EP EP91203182A patent/EP0491415B1/fr not_active Expired - Lifetime
- 1991-12-10 ZA ZA919731A patent/ZA919731B/xx unknown
- 1991-12-11 AU AU89647/91A patent/AU645382B2/en not_active Ceased
- 1991-12-11 NZ NZ240944A patent/NZ240944A/xx not_active IP Right Cessation
- 1991-12-12 PT PT99782A patent/PT99782B/pt not_active IP Right Cessation
- 1991-12-12 CA CA002057528A patent/CA2057528C/fr not_active Expired - Fee Related
- 1991-12-12 NO NO914900A patent/NO179234C/no unknown
- 1991-12-12 US US07/806,966 patent/US5262408A/en not_active Expired - Lifetime
- 1991-12-12 CN CN91111089A patent/CN1036835C/zh not_active Expired - Fee Related
- 1991-12-12 FI FI915855A patent/FI99083C/fi not_active IP Right Cessation
- 1991-12-12 KR KR1019910022726A patent/KR100187316B1/ko not_active Expired - Fee Related
- 1991-12-13 JP JP3330885A patent/JPH04290828A/ja active Pending
1996
- 1996-06-07 GR GR960401541T patent/GR3020179T3/el unknown

Also Published As

Publication number	Publication date
IE914221A1 (en)	1992-06-17
FI99083C (fi)	1997-10-10
IE71203B1 (en)	1997-02-12
US5262408A (en)	1993-11-16
CN1062290A (zh)	1992-07-01
CA2057528A1 (fr)	1992-06-14
KR920011517A (ko)	1992-07-24
PT99782A (pt)	1992-12-31
FI915855L (fi)	1992-06-14
DE69118493T2 (de)	1996-08-22
GR3020179T3 (en)	1996-09-30
JPH04290828A (ja)	1992-10-15
FI915855A0 (fi)	1991-12-12
AU645382B2 (en)	1994-01-13
CA2057528C (fr)	2003-02-04
NZ240944A (en)	1994-05-26
NO914900D0 (no)	1991-12-12
NO914900L (no)	1992-06-15
NO179234B (no)	1996-05-28
AU8964791A (en)	1992-06-18
NO179234C (no)	1996-09-04
EP0491415A1 (fr)	1992-06-24
DK0491415T3 (da)	1996-07-08
DE69118493D1 (de)	1996-05-09
ES2087964T3 (es)	1996-08-01
ATE136218T1 (de)	1996-04-15
CN1036835C (zh)	1997-12-31
EP0491415B1 (fr)	1996-04-03
FI99083B (fi)	1997-06-30
KR100187316B1 (ko)	1999-05-01
PT99782B (pt)	2001-05-31

Publication	Publication Date	Title
AU645382B2 (en)	1994-01-13	Low estrogen oral contraceptives
AU645637B2 (en)	1994-01-20	Contraceptive regimen
NZ333750A (en)	2000-09-29	Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen
RU96115196A (ru)	1998-10-27	Состав для контрацепции
CA2356747A1 (fr)	2000-07-06	Contraceptif oral triphase
HK67393A (en)	1993-07-23	Combination dosage form for pre-menopausal women
NZ332894A (en)	1999-05-28	A regimen containing progestogen and/or estrogen with two or more anti-progestogen dosage units
NZ330741A (en)	2000-03-27	Contraceptive process and kit for female mammals, comprising a combination of gestagen and oestrogen
CA2542854A1 (fr)	2005-06-02	Contraceptif d'oestrogene progressif
NZ333862A (en)	2000-08-25	Triphasic oral contraceptive method and kit comprising a combination of progestin and estrogen
WO1997006807A3 (fr)	1997-03-20	Preparation contraceptive combinee, trousse le contenant et procede de contraception au moyen de cette preparation
ATE249222T1 (de)	2003-09-15	Biphasische orale verhuetungsmethode und kit die eine kombination von progestin und eines oestrogens enthalten
GB1475790A (en)	1977-06-10	Contraceptive method and pack
Hall	1987	Once-a-month injectable contraceptives