ZA925581B - Pharmaceutical microemulsions. - Google Patents

Pharmaceutical microemulsions.

Info

Publication number
ZA925581B
ZA925581B ZA925581A ZA925581A ZA925581B ZA 925581 B ZA925581 B ZA 925581B ZA 925581 A ZA925581 A ZA 925581A ZA 925581 A ZA925581 A ZA 925581A ZA 925581 B ZA925581 B ZA 925581B
Authority
ZA
South Africa
Prior art keywords
microemulsions
hlb surfactant
pharmaceutical
emulsifying
iii
Prior art date
Application number
ZA925581A
Other languages
English (en)
Inventor
Panayiuotis Per Constantinides
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24959558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA925581(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA925581B publication Critical patent/ZA925581B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
ZA925581A 1991-07-26 1992-07-24 Pharmaceutical microemulsions. ZA925581B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73635491A 1991-07-26 1991-07-26

Publications (1)

Publication Number Publication Date
ZA925581B true ZA925581B (en) 1993-05-14

Family

ID=24959558

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925581A ZA925581B (en) 1991-07-26 1992-07-24 Pharmaceutical microemulsions.

Country Status (15)

Country Link
EP (1) EP0597007B1 (da)
JP (1) JPH06509796A (da)
AT (1) ATE144137T1 (da)
AU (1) AU667316B2 (da)
CA (1) CA2114141A1 (da)
DE (1) DE69214652T2 (da)
DK (1) DK0597007T3 (da)
ES (1) ES2093269T3 (da)
GR (1) GR3022260T3 (da)
IL (1) IL102633A0 (da)
MX (1) MX9204379A (da)
NZ (1) NZ243703A (da)
PT (1) PT100726A (da)
WO (1) WO1993002664A1 (da)
ZA (1) ZA925581B (da)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
NZ243721A (en) * 1991-07-26 1994-11-25 Smithkline Beecham Corp Self-emulsifying microemulsion comprising water soluble drug, high hlb surfactant and a lipophilic phase containing fatty acid triglyceride and a low hlb surfactant
AU679013B2 (en) * 1992-10-16 1997-06-19 Ibah, Inc. Convertible microemulsion formulations
WO1994008605A1 (en) * 1992-10-16 1994-04-28 Smithkline Beecham Corporation Therapeutic microemulsions
WO1994008603A1 (en) * 1992-10-16 1994-04-28 Smithkline Beecham Corporation Compositions
EP0684834A4 (en) * 1993-02-17 1996-09-25 Smithkline Beecham Corp MICROEMULSIONS CONTAINING THERAPEUTIC PEPTIDES.
TW438603B (en) * 1993-04-19 2001-06-07 Advanced Skin Res Kenkyusho Kk Microemulsion preparation containing peptide pharmaceuticals
EP0721380B1 (en) * 1993-09-29 1999-05-26 Technobiochip Protein thin films and compositions for use in their preparation
CA2176927C (en) * 1993-11-17 2010-03-23 Seang H. Yiv Transparent liquid for encapsulated drug delivery
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
SE9503143D0 (sv) 1995-09-12 1995-09-12 Astra Ab New preparation
GB9613858D0 (en) 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
TWI241915B (en) * 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
US6242001B1 (en) * 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
WO2000033866A1 (en) * 1998-12-04 2000-06-15 Provalis Uk Limited Pharmaceutical compositions containing insulin
US7169889B1 (en) 1999-06-19 2007-01-30 Biocon Limited Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
US6867183B2 (en) 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en) 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6858580B2 (en) 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7312192B2 (en) 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7196059B2 (en) 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US6913903B2 (en) 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7166571B2 (en) 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
DE60231549D1 (de) 2001-12-03 2009-04-23 Dor Biopharma Inc Stabilisierte umkehr-mizellen-zusammensetzungen und ihre verwendung
RO123110B1 (ro) 2001-12-14 2010-11-30 Jagotec Ag Formulare farmaceutică cu ciclosporină şi utilizarea acesteia
AU2003236521A1 (en) 2002-06-13 2003-12-31 Nobex Corporation Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
US20050232974A1 (en) * 2004-04-19 2005-10-20 Gore Makarand P System and a method for pharmaceutical dosage preparation using jettable microemulsions
CN103223160B (zh) 2004-07-19 2015-02-18 比奥孔有限公司 胰岛素-低聚物共轭物,制剂及其用途
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
WO2006113505A2 (en) 2005-04-15 2006-10-26 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
ITMI20060618A1 (it) * 2006-03-31 2007-10-01 Enitecnologie Spa Procedimento per la preparazione di nanoemulsioni acqua ion olio e olio in acqua
EP1961412A1 (en) 2006-12-27 2008-08-27 LEK Pharmaceuticals D.D. Self-microemulsifying drug delivery systems
US20110144010A1 (en) * 2007-06-01 2011-06-16 Novo Nordisk A/S Spontaneously Dispersible Preconcentrates Including a Peptide Drug in a Solid or Semisolid Carrier
JP5156458B2 (ja) * 2008-03-31 2013-03-06 理研ビタミン株式会社 ソフトカプセル充填用液状組成物
KR101503474B1 (ko) * 2007-09-27 2015-03-18 리켄 비타민 가부시키가이샤 연질 캅셀 충전용 액상 조성물
US9241908B2 (en) 2007-10-16 2016-01-26 Biocon Limited Orally administrable solid pharmaceutical composition and a process thereof
WO2009115469A1 (en) 2008-03-18 2009-09-24 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
WO2011004395A1 (en) * 2009-07-06 2011-01-13 Intas Biopharmaceuticals Limited Microemulsion formulation for biologicals
US20120322776A1 (en) * 2009-12-22 2012-12-20 Leo Pharma A/S Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
US20120058187A1 (en) * 2010-09-03 2012-03-08 Novagali Pharma Sa Water-in-oil type emulsion for treating a disease of the eye
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
GB201107629D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Hydrophobic preparations
CA2870313A1 (en) 2012-04-11 2013-10-17 Novo Nordisk A/S Insulin formulations
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
MX383502B (es) * 2015-12-08 2025-03-14 Luoda Pharma Ltd Métodos y composiciones para el tratamiento de úlceras gástricas
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
US12150945B2 (en) 2018-07-20 2024-11-26 Lipocine Inc. Liver disease
WO2020210723A1 (en) 2019-04-11 2020-10-15 R.P. Scherer Technologies, Llc Formulation for oral delivery of proteins, peptides and small molecules with poor permeability
US11564933B2 (en) 2019-04-12 2023-01-31 Tolmar, Inc. Methods of treating testosterone deficiency

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1080994A (en) * 1963-10-25 1967-08-31 Nat Res Dev Injectable emulsions containing antigens
US4840660A (en) * 1985-12-30 1989-06-20 Rhone Poulenc Nederlands B.V. Plant growth regulator dispersions
IE60024B1 (en) * 1987-02-03 1994-05-18 Stiefel Laboratories Ltd Microemulsions
NZ243721A (en) * 1991-07-26 1994-11-25 Smithkline Beecham Corp Self-emulsifying microemulsion comprising water soluble drug, high hlb surfactant and a lipophilic phase containing fatty acid triglyceride and a low hlb surfactant

Also Published As

Publication number Publication date
EP0597007A1 (en) 1994-05-18
AU2411592A (en) 1993-03-02
ATE144137T1 (de) 1996-11-15
JPH06509796A (ja) 1994-11-02
AU667316B2 (en) 1996-03-21
CA2114141A1 (en) 1993-02-18
DE69214652T2 (de) 1997-03-20
MX9204379A (es) 1993-02-01
DK0597007T3 (da) 1996-11-18
EP0597007B1 (en) 1996-10-16
WO1993002664A1 (en) 1993-02-18
DE69214652D1 (de) 1996-11-21
GR3022260T3 (en) 1997-04-30
ES2093269T3 (es) 1996-12-16
NZ243703A (en) 1995-12-21
IL102633A0 (en) 1993-01-14
PT100726A (pt) 1993-09-30

Similar Documents

Publication Publication Date Title
GR3022260T3 (en) W/o microemulsions.
ZA925580B (en) Pharmaceutical miroemulsions.
DE69403057D1 (de) Zusammensetzung, die bei peroraler verabreichung eine mikroemulsion bildet
KR100666016B1 (ko) 테스토스테론 운데카노에이트 및 피마자유를 포함하는 제제
ZA966067B (en) New pharmaceutical dosage formulations of fenofibrate and their applications
GB9616237D0 (en) Aerosol formulations
AP2000001943A0 (en) Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
CA2072509A1 (en) Cyclosporin emulsion compositions for oral administration
ES2186715T3 (es) Uso de un tensioactivo lipofilico en una composicion farmaceutica.
EP1736147A3 (en) Non-chlorofluorocarbon aerosol formulations
CA2111002A1 (en) Non-Chlorofluorocarbon Aerosol Formulations
DE69332078D1 (de) Arzneimittel enthaltende cyclosporinderivate
RU2001124597A (ru) Спонтанно диспергирующиеся композиции, содержащие N-бензоилстауроспорин
GR3034191T3 (en) Formulations for lipophilic compounds
AU5347596A (en) External preparations for treating dermatoses
CA2362277A1 (en) Spontaneously dispersible n-benzoyl staurosporine compositions
WO2001064187A8 (en) Anaesthetic formulations
GB9100928D0 (en) Retrievable pessary
NZ313899A (en) Oral cyclosporin compositions comprising cyclosporin A, a solvent either ethanol or propylene glycol and one non-ionic polyoxyethylene surfactant selected from polyoxyethylene alcohols and mono-esters of ethoxylated sorbitans
IT1317871B1 (it) Sistemi terapeutici per forme farmaceutiche orali di principi attiviaventi sfavorevoli caratteristiche organolettiche.
MX9604004A (es) Formualciones de farmaco en aerosol que contienen vitamina e.