ZA928995B - Ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number: ZA928995B
Authority: ZA; South Africa
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; benzoate compounds; ethanolamine benzoate
Prior art date: 1991-11-22

Application number

ZA928995A

Other languages

English (en)

Inventor

Michel Wierzbicki

Pierre Hugon

Jacques Duhault

Michelle Boulanger

Francoise Lacour

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-22

Filing date

1992-11-20

Publication date

1993-05-25

1992-11-20 Application filed by Adir filed Critical Adir

1993-05-25 Publication of ZA928995B publication Critical patent/ZA928995B/xx

Links

JOTMFOWEVMXFHO-UHFFFAOYSA-N 2-aminoethyl benzoate Chemical class NCCOC(=O)C1=CC=CC=C1 JOTMFOWEVMXFHO-UHFFFAOYSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
206010020772 Hypertension Diseases 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
206010060378 Hyperinsulinaemia Diseases 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
230000003451 hyperinsulinaemic effect Effects 0.000 abstract 1
201000008980 hyperinsulinism Diseases 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
230000006371 metabolic abnormality Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA928995A 1991-11-22 1992-11-20 Ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them. ZA928995B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9114357A FR2684101B1 (fr)	1991-11-22	1991-11-22	Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number	Publication Date
ZA928995B true ZA928995B (en)	1993-05-25

Family

ID=9419177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA928995A ZA928995B (en)	1991-11-22	1992-11-20	Ethanolamine benzoate compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (13)

Country	Link
US (1)	US5266591A (de)
EP (1)	EP0543713B1 (de)
JP (1)	JPH0694447B2 (de)
AT (1)	ATE118759T1 (de)
AU (1)	AU649896B2 (de)
CA (1)	CA2083475C (de)
DE (1)	DE69201480T2 (de)
DK (1)	DK0543713T3 (de)
ES (1)	ES2072118T3 (de)
FR (1)	FR2684101B1 (de)
GR (1)	GR3015794T3 (de)
NZ (1)	NZ245201A (de)
ZA (1)	ZA928995B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2677647B1 (fr) *	1991-06-14	1993-08-20	Adir	Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
AU7947594A (en) *	1993-10-27	1995-05-22	Merck Sharp & Dohme Limited	Substituted amides as tachykinin antagonists
RU2153873C2 (ru) *	1994-08-09	2000-08-10	Кортендо АБ	Применение кетоконазола и родственных веществ в лекарствах, предназначенных для лечения диабета типа ii
US7056890B2 (en) *	1999-06-14	2006-06-06	Vivus, Inc.	Combination therapy for effecting weight loss and treating obesity
WO2000076493A1 (en) *	1999-06-14	2000-12-21	Thomas Najarian	Combination therapy for effecting weight loss and treating obesity
US7659256B2 (en) *	1999-06-14	2010-02-09	Vivus, Inc.	Combination therapy for effecting weight loss and treating obesity
US7674776B2 (en) *	1999-06-14	2010-03-09	Vivus, Inc.	Combination therapy for effecting weight loss and treating obesity
US7553818B2 (en) *	1999-06-14	2009-06-30	Vivus, Inc.	Combination therapy for effecting weight loss and treating obesity
US20080103179A1 (en) *	2006-10-27	2008-05-01	Tam Peter Y	Combination Therapy
US20080255093A1 (en) *	1999-06-14	2008-10-16	Tam Peter Y	Compositions and methods for treating obesity and related disorders
US20090304789A1 (en)	2008-06-09	2009-12-10	Thomas Najarian	Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders
US8580298B2 (en)	2008-06-09	2013-11-12	Vivus, Inc.	Low dose topiramate/phentermine composition and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1175516A (en) *	1966-04-15	1969-12-23	Science Union & Cie	New Phenyl-Aminopropane Derivatives and Preparations Containing them
DE2629752A1 (de) *	1976-07-02	1978-01-05	Boehringer Mannheim Gmbh	Neue carbonsaeurederivate und verfahren zu ihrer herstellung
US4237165A (en) *	1976-06-04	1980-12-02	Science Union Et Cie	Treatment of carbohydrate metabolism disorders

1991
- 1991-11-22 FR FR9114357A patent/FR2684101B1/fr not_active Expired - Fee Related
1992
- 1992-11-16 ES ES92403073T patent/ES2072118T3/es not_active Expired - Lifetime
- 1992-11-16 EP EP92403073A patent/EP0543713B1/de not_active Expired - Lifetime
- 1992-11-16 DK DK92403073.7T patent/DK0543713T3/da active
- 1992-11-16 AT AT92403073T patent/ATE118759T1/de not_active IP Right Cessation
- 1992-11-16 DE DE69201480T patent/DE69201480T2/de not_active Expired - Fee Related
- 1992-11-20 CA CA002083475A patent/CA2083475C/fr not_active Expired - Fee Related
- 1992-11-20 NZ NZ245201A patent/NZ245201A/en unknown
- 1992-11-20 ZA ZA928995A patent/ZA928995B/xx unknown
- 1992-11-20 AU AU28548/92A patent/AU649896B2/en not_active Ceased
- 1992-11-20 US US07/979,202 patent/US5266591A/en not_active Expired - Fee Related
- 1992-11-20 JP JP4312324A patent/JPH0694447B2/ja not_active Expired - Lifetime
1995
- 1995-04-17 GR GR950400924T patent/GR3015794T3/el unknown

Also Published As

Publication number	Publication date
GR3015794T3 (en)	1995-07-31
CA2083475C (fr)	1998-09-08
NZ245201A (en)	1995-07-26
DE69201480T2 (de)	1995-10-05
DK0543713T3 (da)	1995-07-24
FR2684101A1 (fr)	1993-05-28
ES2072118T3 (es)	1995-07-01
JPH0694447B2 (ja)	1994-11-24
EP0543713A1 (de)	1993-05-26
FR2684101B1 (fr)	1993-12-31
EP0543713B1 (de)	1995-02-22
ATE118759T1 (de)	1995-03-15
AU2854892A (en)	1993-05-27
DE69201480D1 (de)	1995-03-30
AU649896B2 (en)	1994-06-02
CA2083475A1 (fr)	1993-05-23
JPH05221943A (ja)	1993-08-31
US5266591A (en)	1993-11-30

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AU8794291A (en)	1992-05-21	New oxazolopyridine derivatives, processes for preparing these and pharmaceutical compositions containing them
ZA831452B (en)	1983-11-30	Cephalosporing derivatives,and a process for their preparation
DE69111582D1 (de)	1995-08-31	1,4-Disubstituierte Piperazine, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen.
GR3015794T3 (en)	1995-07-31	Ethanolamine benzoate derivatives, process for their preparation and pharmaceutical compositions containing them.
AU2453792A (en)	1993-03-25	New trimetazidine compounds, a process for their preparation and pharmaceutical compositions containing them
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