ZA931263B - Reaction-based selection for expression of and concentration of catalytic moieties - Google Patents

Reaction-based selection for expression of and concentration of catalytic moieties

Info

Publication number
ZA931263B
ZA931263B ZA931263A ZA931263A ZA931263B ZA 931263 B ZA931263 B ZA 931263B ZA 931263 A ZA931263 A ZA 931263A ZA 931263 A ZA931263 A ZA 931263A ZA 931263 B ZA931263 B ZA 931263B
Authority
ZA
South Africa
Prior art keywords
catalytic
population
expression
reaction
based selection
Prior art date
Application number
ZA931263A
Other languages
English (en)
Inventor
Gary F Blackburn
David M Simpson
Rodger G Smith
Mark T Martin
Michael J Darsley
Original Assignee
Igen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Igen Inc filed Critical Igen Inc
Publication of ZA931263B publication Critical patent/ZA931263B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Sampling And Sample Adjustment (AREA)
ZA931263A 1992-02-24 1993-02-23 Reaction-based selection for expression of and concentration of catalytic moieties ZA931263B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84164892A 1992-02-24 1992-02-24

Publications (1)

Publication Number Publication Date
ZA931263B true ZA931263B (en) 1993-11-02

Family

ID=25285377

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA931263A ZA931263B (en) 1992-02-24 1993-02-23 Reaction-based selection for expression of and concentration of catalytic moieties

Country Status (12)

Country Link
US (4) US5631137A (de)
EP (2) EP0631633B1 (de)
JP (1) JP4125365B2 (de)
KR (1) KR100233950B1 (de)
AT (1) ATE221578T1 (de)
AU (1) AU675783B2 (de)
CA (1) CA2125405A1 (de)
DE (1) DE69332168T2 (de)
ES (1) ES2180543T3 (de)
IL (1) IL104829A (de)
WO (1) WO1993017124A1 (de)
ZA (1) ZA931263B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030069173A1 (en) * 1998-03-16 2003-04-10 Life Technologies, Inc. Peptide-enhanced transfections
US6156541A (en) * 1995-07-21 2000-12-05 The Board Of Regents Of The University Of Nebraska Compositions and methods for catalyzing hydrolysis of HIV gp120
EP0854933B1 (de) 1995-09-07 2003-05-07 Novozymes A/S Nachweis der aktivität von enzymen für detergenzien durch phagen.
CA2249455A1 (en) * 1996-03-26 1997-10-02 Amrad Operations Pty. Ltd. Precursors of catalytic antibodies
AUPO930697A0 (en) * 1997-09-19 1997-10-09 Walter And Eliza Hall Institute Of Medical Research, The Catalytic antibodies and a method of producing same
CN1314952A (zh) * 1998-08-19 2001-09-26 诺维信公司 直接通过底物再加载进行的酶活性筛选
AU2002308633A1 (en) 2001-05-09 2002-11-18 Monsanto Technology Llc Metabolite transporters
EP1950305A1 (de) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr-A-Gene und ihre Verwendung
FR2831836B1 (fr) * 2001-11-08 2004-04-23 Inst Nat Polytech Grenoble Procede de formation de sites catalytiques sur la surface d'un support
AU2003215388A1 (en) * 2002-02-22 2003-09-09 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
EP1532274A4 (de) * 2002-06-28 2006-09-27 Purdue Research Foundation Magnetische nanomaterialien und verfahren zum nachweis biologischer materialien

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3745285A (en) * 1983-11-29 1985-06-13 Igen, Inc. Method of catalyzing chemical reactions
BE1006312A3 (fr) * 1991-11-29 1994-07-19 Univ Catholique Louvain Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique.

Also Published As

Publication number Publication date
JP4125365B2 (ja) 2008-07-30
AU675783B2 (en) 1997-02-20
US5631137A (en) 1997-05-20
US6121007A (en) 2000-09-19
EP1203824A2 (de) 2002-05-08
EP0631633A1 (de) 1995-01-04
AU3776193A (en) 1993-09-13
IL104829A (en) 1999-04-11
US6177270B1 (en) 2001-01-23
IL104829A0 (en) 1993-06-10
CA2125405A1 (en) 1993-09-02
EP0631633B1 (de) 2002-07-31
US5891648A (en) 1999-04-06
ES2180543T3 (es) 2003-02-16
KR950700424A (ko) 1995-01-16
ATE221578T1 (de) 2002-08-15
EP0631633A4 (de) 1998-02-25
KR100233950B1 (ko) 1999-12-15
DE69332168D1 (de) 2002-09-05
EP1203824A3 (de) 2005-02-23
WO1993017124A1 (en) 1993-09-02
DE69332168T2 (de) 2003-03-20
JPH07504090A (ja) 1995-05-11

Similar Documents

Publication Publication Date Title
AU3882689A (en) Carrier matrix with dissolvably impregnated reagent
AU5984790A (en) Method and apparatus for heterogeneous chemiluminescence assay
EP0295073A3 (de) Chromatographisches Material
IL104829A0 (en) Reaction-based selection for expression of and concentration of catalytic moieties
AU2241488A (en) Process for the catalytic conversion of offgases containing hydrocarbons and carbon monoxide
GB2201904B (en) Device for liquid chromatography or immobilised enzyme reaction
EP0366448A3 (de) Verfahren zum Nachweis und zur Identifizierung von Nukleinsäure enthaltenden Teilen
ATE89827T1 (de) Verfahren zur reinigung von nukleinsaeuren.
EP0184454A3 (de) Immobilisierte Antikörpersysteme und ihre Herstellung
GR3014996T3 (en) Test method and reagent kit therefor.
GR3029784T3 (en) Sensor for optical assay.
JPS6435375A (en) Binder composition and element for analysis having stabilized peroxidase in layer containing the same
CA2134357A1 (en) Nucleic acid probes to mycobacterium tuberculosis
CA2097545A1 (en) Process for the immunochemical determination of an analyte
JPS6488367A (en) Immobilized antibody
JPS55162399A (en) Method of optimizing activity of metabolism of microbe in substrate of biological reaction system
AU2462388A (en) Method for self-performing enzyme kinetics
ATE76082T1 (de) Reinigungsmethode fuer antikoerper.
AU1493995A (en) Monoclonal antibody
JPS54132291A (en) Novel bioreactor
AU5057785A (en) A method for determining a ligand
EP0311388A3 (de) Schnelles Verfahren zur Identifizierung einer spezifischen Sequenz von Nukleinsäure
AU2562088A (en) Detection of tumor-associated markers in biological fluids
AU8781791A (en) Process for selective removal of salivary alpha-amylase and assay for pancreatic alpha-amylase
DE3564260D1 (en) 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof