ZA938947B - Fatty acid derivatives and pharmaceutical compositions containing them - Google Patents

Fatty acid derivatives and pharmaceutical compositions containing them

Info

Publication number
ZA938947B
ZA938947B ZA938947A ZA938947A ZA938947B ZA 938947 B ZA938947 B ZA 938947B ZA 938947 A ZA938947 A ZA 938947A ZA 938947 A ZA938947 A ZA 938947A ZA 938947 B ZA938947 B ZA 938947B
Authority
ZA
South Africa
Prior art keywords
fatty acid
pharmaceutical compositions
compositions containing
acid derivatives
derivatives
Prior art date
Application number
ZA938947A
Other languages
English (en)
Inventor
Raphael Mechoulam
Aviva Beuer
Lumir Hanus
William S Devane
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Publication of ZA938947B publication Critical patent/ZA938947B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA938947A 1992-11-30 1993-11-30 Fatty acid derivatives and pharmaceutical compositions containing them ZA938947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10393292A IL103932A (en) 1992-11-30 1992-11-30 Fatty acid and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ZA938947B true ZA938947B (en) 1994-08-02

Family

ID=11064282

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938947A ZA938947B (en) 1992-11-30 1993-11-30 Fatty acid derivatives and pharmaceutical compositions containing them

Country Status (13)

Country Link
EP (1) EP0670826B1 (fr)
JP (1) JPH08504195A (fr)
CN (1) CN1097735A (fr)
AU (1) AU5733494A (fr)
CZ (1) CZ136195A3 (fr)
DE (1) DE69328492T2 (fr)
ES (1) ES2145118T3 (fr)
HU (1) HUT73177A (fr)
IL (1) IL103932A (fr)
PL (1) PL309051A1 (fr)
SK (1) SK70895A3 (fr)
WO (1) WO1994012466A1 (fr)
ZA (1) ZA938947B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631297A (en) * 1994-07-11 1997-05-20 Pate; David W. Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same
WO1996001558A1 (fr) * 1994-07-11 1996-01-25 Pate David W Compositions d'analogues d'anandamide et procede de traitement de l'hypertension intra-oculaire a l'aide de telles compositions
IT1271267B (it) * 1994-12-14 1997-05-27 Valle Francesco Della Ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi
DE19544635A1 (de) * 1995-11-30 1997-06-05 Boehringer Mannheim Gmbh Neue Aminoalkoholderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19706903A1 (de) * 1997-02-21 1998-08-27 Bayer Ag Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1
WO1999051560A1 (fr) * 1998-04-03 1999-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Analogues de cannabinoides endogenes synthetiques et leurs utilisations
EP1645270B1 (fr) * 1998-05-29 2010-04-28 Neurosciences Research Foundation Inc. Elimination de la douleur au moyen d'anandamide
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
CA2635412C (fr) 1998-08-17 2011-06-21 Senju Pharmaceutical Co., Ltd. Agent destine a la prophylaxie et au traitement de l'asthenopie ou de la pseudomyopie
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
AU1833600A (en) * 1998-11-24 2000-06-19 Andreas Goutopoulos Cannabimimetic lipid amides as useful medications
GB9923738D0 (en) 1999-10-07 1999-12-08 Nestle Sa Nutritional composition
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6974568B2 (en) 2000-05-23 2005-12-13 The Regents Of The University Of California Treatment for cough
NO20006008L (no) * 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
US8449908B2 (en) 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
CA2435409A1 (fr) 2001-01-26 2002-08-01 University Of Connecticut Nouveaux ligands cannabimimetiques
KR20030087657A (ko) 2001-03-27 2003-11-14 더 리전츠 오브 더 유니버시티 오브 캘리포니아 체지방 감소 및 지방산 대사 조절을 위한 방법, 화합물 및조성물
EP1414775B1 (fr) 2001-07-13 2012-12-19 The University of Connecticut Cannabinoide bicyclique
WO2003008632A1 (fr) * 2001-07-16 2003-01-30 Hoegestaett Edward Conjugaison d'acides gras en tant que methode de criblage de substances potentiellement bioactives
CA2478338A1 (fr) 2002-03-08 2003-09-18 Signal Pharmaceuticals, Inc. Polytherapie destinee a traiter, prevenir ou gerer des troubles proliferatifs et des cancers
WO2004103410A1 (fr) 2002-06-06 2004-12-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions de procedes et articles de fabrication destines a moduler la croissance osseuse
ITMI20030210A1 (it) * 2003-02-07 2004-08-08 Res & Innovation Soc Coop A R L Composti endocannabinoido-simili e loro impiego
US7276608B2 (en) 2003-07-11 2007-10-02 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
US7326706B2 (en) 2003-08-15 2008-02-05 Bristol-Myers Squibb Company Pyrazine modulators of cannabinoid receptors
IL160420A0 (en) 2004-02-16 2004-07-25 Yissum Res Dev Co Treating or preventing diabetes with cannabidiol
CA2650900A1 (fr) * 2006-05-01 2007-11-15 Eastern Virginia Medical School Nouveaux cannabinoides et procedes d'utilisation
WO2008139263A2 (fr) * 2006-11-30 2008-11-20 University Of Plymouth Procédés pour ralentir la progression de la sclérose en plaques
ES2534900T3 (es) 2007-07-30 2015-04-30 Zynerba Pharmaceuticals, Inc. Profármacos de cannabidiol, composiciones que comprenden los profármacos de cannabidiol y métodos de uso de los mismos
EP2262763A2 (fr) 2008-03-04 2010-12-22 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Composes et procedes pour le traitement de l'obesite
WO2010013240A1 (fr) * 2008-07-31 2010-02-04 Dekel Pharmaceuticals Ltd. Compositions et procédés de traitement de troubles inflammatoires
ES2549924T3 (es) * 2009-11-25 2015-11-03 Cytometix, Inc. Análogos de ácido araquidónico y métodos para tratamiento analgésico usando el mismo
CN103877100B (zh) * 2013-05-21 2016-08-10 成都旗美健康食品有限公司 亚麻酸酰基乙醇胺的联合医用和保健用药物
AU2020260090C9 (en) 2019-04-15 2023-08-31 Metagenics LLC Novel hemp and PEA formulation and its use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE306730B (fr) * 1963-02-06 1968-12-09 Sumitomo Chemical Co
SE353319B (fr) * 1964-08-15 1973-01-29 Sumitomo Chemical Co
US4619938A (en) * 1984-03-21 1986-10-28 Terumo Kabushiki Kaisha Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors
NZ216751A (en) * 1985-07-05 1990-01-29 Cird Eicosatriynoic acid esters and amides,pharmaceutical compositions and process for preparing eicosatriynoic acid

Also Published As

Publication number Publication date
CZ136195A3 (en) 1995-11-15
EP0670826A4 (fr) 1996-08-14
CN1097735A (zh) 1995-01-25
WO1994012466A1 (fr) 1994-06-09
HU9501561D0 (en) 1995-07-28
SK70895A3 (en) 1995-09-13
IL103932A (en) 1997-02-18
JPH08504195A (ja) 1996-05-07
HUT73177A (en) 1996-06-28
DE69328492T2 (de) 2000-09-07
EP0670826B1 (fr) 2000-04-26
IL103932A0 (en) 1993-04-04
AU5733494A (en) 1994-06-22
DE69328492D1 (de) 2000-05-31
PL309051A1 (en) 1995-09-18
EP0670826A1 (fr) 1995-09-13
ES2145118T3 (es) 2000-07-01

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