ZA963788B - Process for the preparation of 5-amino-2,4, 6-triiodoisoph-thalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst - Google Patents

Process for the preparation of 5-amino-2,4, 6-triiodoisoph-thalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst

Info

Publication number: ZA963788B
Authority: ZA; South Africa
Prior art keywords: triiodoisoph; chlorination; catalyst; amino; preparation
Prior art date: 1995-05-18

Application number

ZA963788A

Other languages

English (en)

Inventor

Marco Villa

Claudio Pozzoli

Lauro Russo

Graziano Castaldi

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-18

Filing date

1996-05-13

Publication date

1996-09-05

1996-05-13 Application filed by Zambon Spa filed Critical Zambon Spa

1996-09-05 Publication of ZA963788B publication Critical patent/ZA963788B/xx

Links

FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 title 2
JEZJSNULLBSYHV-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(I)C(C(O)=O)=C(I)C(C(O)=O)=C1I JEZJSNULLBSYHV-UHFFFAOYSA-N 0.000 title 1
239000003054 catalyst Substances 0.000 title 1
238000005660 chlorination reaction Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Indole Compounds (AREA)

ZA963788A 1995-05-18 1996-05-13 Process for the preparation of 5-amino-2,4, 6-triiodoisoph-thalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst ZA963788B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI951004A IT1275429B (it)	1995-05-18	1995-05-18	Processo per la preparazione di un intermedio utile nella sintesi di composti organici

Publications (1)

Publication Number	Publication Date
ZA963788B true ZA963788B (en)	1996-09-05

Family

ID=11371619

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA963788A ZA963788B (en)	1995-05-18	1996-05-13	Process for the preparation of 5-amino-2,4, 6-triiodoisoph-thalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst

Country Status (20)

Country	Link
US (1)	US5663432A (it)
JP (1)	JP3865405B2 (it)
AU (1)	AU5895096A (it)
BE (1)	BE1009466A3 (it)
CA (1)	CA2221278C (it)
CH (1)	CH691534A5 (it)
CZ (1)	CZ287815B6 (it)
DE (1)	DE19681399B4 (it)
DK (1)	DK176046B1 (it)
FR (1)	FR2734262B1 (it)
GB (1)	GB2315751B (it)
HU (1)	HUP9801142A3 (it)
IE (1)	IE80674B1 (it)
IL (1)	IL118062A (it)
IT (1)	IT1275429B (it)
NL (1)	NL1003127C2 (it)
NO (1)	NO310286B1 (it)
SE (1)	SE520616C2 (it)
WO (1)	WO1996036590A1 (it)
ZA (1)	ZA963788B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101307010B (zh) *	2008-07-12	2011-05-25	厦门大学	碘佛醇的合成方法
PT105770B (pt) *	2011-06-24	2013-07-08	Hovione Farmaciencia S A	Novo intermediário e seu uso na preparação de agente de contrate triiodado
CA2897700C (en)	2012-12-11	2022-05-03	Bracco Imaging S.P.A.	Continuous process for the preparation of (s)-2-acetyloxypropionic acid chloride
DK3154928T3 (da)	2014-06-10	2020-05-18	Bracco Imaging Spa	Fremgangsmåde til fremstilling af (s)-2-acetyloxypropionsyre og derivater deraf
US10508072B2 (en)	2015-10-02	2019-12-17	Zeon Corporation	Method for producing acid halide solution, mixed solution, and method for producing monoester compound
US10633323B2 (en)	2016-01-26	2020-04-28	Zeon Corporation	Method of producing acid halide solution and method of producing monoester compound
US10342232B1 (en)	2018-10-24	2019-07-09	The United States Of America As Represented By The Secretary Of The Navy	Iodinated polymers for biological agent defeat

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR825418A (fr) *	1936-08-10	1938-03-03	Bosch Robert	Pompe à combustibles liquides
US3655752A (en) *	1969-06-20	1972-04-11	Sterling Drug Inc	Isomers of 2 4 6-trihalo-n n n' n'-tetraalkylisophthalamides
CH608189A5 (it) *	1974-12-13	1978-12-29	Savac Ag
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
US4396598A (en) *	1982-01-11	1983-08-02	Mallinckrodt, Inc.	Triiodoisophthalamide X-ray contrast agent
FR2541676A1 (fr) *	1983-02-25	1984-08-31	Guerbet Sa	Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
US5075502A (en) *	1989-12-13	1991-12-24	Mallinckrodt, Inc.	Nonionic x-ray contrast agents, compositions and methods
WO1993010825A1 (en) *	1991-12-03	1993-06-10	Mallinckrodt Medical, Inc.	Nonionic x-ray contrast agents, compositions and methods
IT1271107B (it) *	1994-11-29	1997-05-26	Zambon Spa	Processo per la preparazione di un intermedio utile nella sintesi di composti organici

1995
- 1995-05-18 IT ITMI951004A patent/IT1275429B/it active IP Right Grant
1996
- 1996-04-29 IL IL11806296A patent/IL118062A/xx not_active IP Right Cessation
- 1996-05-09 FR FR9605773A patent/FR2734262B1/fr not_active Expired - Lifetime
- 1996-05-10 HU HU9801142A patent/HUP9801142A3/hu unknown
- 1996-05-10 GB GB9724181A patent/GB2315751B/en not_active Expired - Lifetime
- 1996-05-10 DE DE19681399T patent/DE19681399B4/de not_active Expired - Lifetime
- 1996-05-10 CA CA002221278A patent/CA2221278C/en not_active Expired - Lifetime
- 1996-05-10 AU AU58950/96A patent/AU5895096A/en not_active Abandoned
- 1996-05-10 JP JP53453196A patent/JP3865405B2/ja not_active Expired - Lifetime
- 1996-05-10 WO PCT/EP1996/002009 patent/WO1996036590A1/en not_active Ceased
- 1996-05-10 DK DK199701303A patent/DK176046B1/da not_active IP Right Cessation
- 1996-05-10 CZ CZ19973633A patent/CZ287815B6/cs not_active IP Right Cessation
- 1996-05-10 CH CH02665/97A patent/CH691534A5/de not_active IP Right Cessation
- 1996-05-13 ZA ZA963788A patent/ZA963788B/xx unknown
- 1996-05-15 NL NL1003127A patent/NL1003127C2/nl not_active IP Right Cessation
- 1996-05-17 IE IE960350A patent/IE80674B1/en not_active IP Right Cessation
- 1996-05-17 US US08/649,490 patent/US5663432A/en not_active Expired - Lifetime
- 1996-05-20 BE BE9600446A patent/BE1009466A3/fr not_active IP Right Cessation
1997
- 1997-11-17 SE SE9704190A patent/SE520616C2/sv unknown
- 1997-11-17 NO NO19975260A patent/NO310286B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ITMI951004A1 (it)	1996-11-18
SE9704190D0 (sv)	1997-11-17
IL118062A (en)	2001-03-19
CZ287815B6 (en)	2001-02-14
AU5895096A (en)	1996-11-29
DE19681399B4 (de)	2008-08-28
CA2221278C (en)	2008-12-02
CA2221278A1 (en)	1996-11-21
IE80674B1 (en)	1998-11-18
JPH11505234A (ja)	1999-05-18
ITMI951004A0 (it)	1995-05-18
NL1003127C2 (nl)	1999-08-25
GB2315751B (en)	1999-04-14
DK130397A (da)	1997-11-17
NL1003127A1 (nl)	1996-11-19
GB9724181D0 (en)	1998-01-14
FR2734262A1 (fr)	1996-11-22
WO1996036590A1 (en)	1996-11-21
HUP9801142A3 (en)	1998-09-28
DK176046B1 (da)	2006-02-20
HUP9801142A1 (hu)	1998-08-28
NO310286B1 (no)	2001-06-18
NO975260L (no)	1997-11-17
CZ363397A3 (cs)	1998-04-15
FR2734262B1 (fr)	1997-08-29
IT1275429B (it)	1997-08-07
IL118062A0 (en)	1996-08-04
US5663432A (en)	1997-09-02
JP3865405B2 (ja)	2007-01-10
DE19681399T1 (de)	1998-05-20
CH691534A5 (de)	2001-08-15
GB2315751A (en)	1998-02-11
SE520616C2 (sv)	2003-07-29
SE9704190L (sv)	1997-11-17
IE960350A1 (en)	1996-11-27
NO975260D0 (no)	1997-11-17
BE1009466A3 (fr)	1997-04-01

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