ZA964014B - Cyclic peptide antifungal agents. - Google Patents

Cyclic peptide antifungal agents.

Info

Publication number
ZA964014B
ZA964014B ZA9604014A ZA964014A ZA964014B ZA 964014 B ZA964014 B ZA 964014B ZA 9604014 A ZA9604014 A ZA 9604014A ZA 964014 A ZA964014 A ZA 964014A ZA 964014 B ZA964014 B ZA 964014B
Authority
ZA
South Africa
Prior art keywords
antifungal agents
cyclic peptide
peptide antifungal
cyclic
agents
Prior art date
Application number
ZA9604014A
Other languages
English (en)
Inventor
James Andrew Jamison
Michael John Rodriguez
Lisa Marie Hammond Lagrandeur
Jr William Wilson Turner
Mark James Zweifel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA964014B publication Critical patent/ZA964014B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9604014A 1995-05-26 1996-05-20 Cyclic peptide antifungal agents. ZA964014B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45305295A 1995-05-26 1995-05-26

Publications (1)

Publication Number Publication Date
ZA964014B true ZA964014B (en) 1997-11-20

Family

ID=23799020

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9604014A ZA964014B (en) 1995-05-26 1996-05-20 Cyclic peptide antifungal agents.

Country Status (13)

Country Link
US (1) US5652213A (de)
EP (1) EP0744405B1 (de)
JP (1) JPH11505845A (de)
AR (1) AR002103A1 (de)
AT (1) ATE245162T1 (de)
AU (1) AU5799196A (de)
CA (1) CA2220728A1 (de)
DE (1) DE69629075T2 (de)
ES (1) ES2201154T3 (de)
IL (1) IL118334A0 (de)
PE (1) PE38497A1 (de)
WO (1) WO1996037510A1 (de)
ZA (1) ZA964014B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997027864A1 (en) * 1996-02-01 1997-08-07 Eli Lilly And Company Cyclic peptide antifungal agents
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
ES2233070T3 (es) 1998-08-20 2005-06-01 ELI LILLY & COMPANY Sintesis de analogos peptidicos ciclicos modificados en el anillo.
WO2000020441A2 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Cyclic peptides as antifungal agents
DE69933046T2 (de) 1998-12-09 2007-09-13 Eli Lilly And Co., Indianapolis Reinigung von echinocandin cyclopeptiden
AU767357B2 (en) * 1998-12-16 2003-11-06 Eli Lilly And Company Cyclic peptide antifungal agents
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
AU767956B2 (en) * 1999-03-03 2003-11-27 Eli Lilly And Company Formation and anion-exchange of crystalline echinocandin ammonium salts
EP1582204B1 (de) * 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmazeutische Zusammensetzungen enthaltend Mizellen bildende Tenside
KR20020003864A (ko) * 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
EP2470190A4 (de) * 2009-08-27 2013-07-17 Seachaid Pharmaceuticals Inc Echinocandinderivate
ES2645074T3 (es) 2011-03-03 2017-12-04 Cidara Therapeutics, Inc. Agentes antifúngicos y sus usos
RU2639483C2 (ru) 2012-03-19 2017-12-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
EP2883915A1 (de) * 2013-12-13 2015-06-17 Ecole Polytechnique Federale de Lausanne (EPFL) Porphyrinbasierter Sensibilisator für farbstoffsensibilisierte Solarzelle
CN108883152A (zh) 2016-01-08 2018-11-23 奇达拉治疗公司 防止和治疗肺孢子虫感染的方法
WO2017161016A1 (en) 2016-03-16 2017-09-21 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
US11197909B2 (en) 2017-07-12 2021-12-14 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
US12466856B2 (en) * 2019-12-06 2025-11-11 Shanghai Senhui Medicine Co., Ltd. Echinocandin analogues and preparation method therefor
US20240262866A1 (en) * 2021-06-03 2024-08-08 Shanghai Senhui Medicine Co., Ltd. Method for preparing anidulafungin derivative
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4320052A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) * 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
IE990233A1 (en) * 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US5233023A (en) * 1991-07-30 1993-08-03 Merck & Co., Inc. Process for phosphate ester compounds of certain cyclohexapeptides
US6030944A (en) * 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
US5399552A (en) * 1991-10-17 1995-03-21 Merck & Co, Inc Antibiotic peptides bearing aminoalkylthioether moieties
NZ247149A (en) * 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof
US6268338B1 (en) * 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
CA2161149A1 (en) * 1993-05-04 1994-11-10 James M. Balkovec Cyclohexapeptidyl aminoalkyl ethers
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use

Also Published As

Publication number Publication date
ES2201154T3 (es) 2004-03-16
PE38497A1 (es) 1997-10-09
US5652213A (en) 1997-07-29
EP0744405A3 (de) 1998-05-27
DE69629075T2 (de) 2004-04-15
EP0744405B1 (de) 2003-07-16
JPH11505845A (ja) 1999-05-25
WO1996037510A1 (en) 1996-11-28
IL118334A0 (en) 1996-09-12
AU5799196A (en) 1996-12-11
AR002103A1 (es) 1998-01-07
EP0744405A2 (de) 1996-11-27
DE69629075D1 (de) 2003-08-21
ATE245162T1 (de) 2003-08-15
CA2220728A1 (en) 1996-11-28

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