ZA964207B - Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor - Google Patents

Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor

Info

Publication number
ZA964207B
ZA964207B ZA964207A ZA964207A ZA964207B ZA 964207 B ZA964207 B ZA 964207B ZA 964207 A ZA964207 A ZA 964207A ZA 964207 A ZA964207 A ZA 964207A ZA 964207 B ZA964207 B ZA 964207B
Authority
ZA
South Africa
Prior art keywords
induce
growth factor
immune response
factor receptor
epidermal growth
Prior art date
Application number
ZA964207A
Other languages
English (en)
Inventor
Ana Carceller
Elisabet Rosell
Alicia Gomez
Jaume Adan
Jaume Piulats
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA964207B publication Critical patent/ZA964207B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA964207A 1995-05-26 1996-05-24 Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor ZA964207B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95107967 1995-05-26

Publications (1)

Publication Number Publication Date
ZA964207B true ZA964207B (en) 1996-12-04

Family

ID=8219291

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA964207A ZA964207B (en) 1995-05-26 1996-05-24 Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor

Country Status (15)

Country Link
US (1) US5969107A (de)
JP (1) JPH08325299A (de)
KR (1) KR960040375A (de)
CN (1) CN1142505A (de)
AT (1) ATE208403T1 (de)
AU (1) AU710159B2 (de)
CA (1) CA2177328A1 (de)
CZ (1) CZ289357B6 (de)
DE (1) DE69616651D1 (de)
HU (1) HUP9601392A3 (de)
MX (1) MX9601930A (de)
NO (1) NO962125L (de)
PL (1) PL314414A1 (de)
SK (1) SK67496A3 (de)
ZA (1) ZA964207B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924359B1 (en) 1999-07-01 2005-08-02 Yale University Neovascular-targeted immunoconjugates
DK1733736T3 (en) * 2001-02-07 2015-06-01 Wilex Ag A process for the production of recombinant antibodies to tumors
US20030232741A1 (en) * 2002-05-06 2003-12-18 Washington University Methods of treatment of glaucoma and other conditions mediated by NOS-2 expression via inhibition of the EGFR pathway
KR20130065723A (ko) 2003-06-27 2013-06-19 암젠 프레몬트 인코포레이티드 상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그 용도
CN101605561A (zh) * 2006-12-22 2009-12-16 诺韦利克斯治疗有限公司 通过至少一种表皮生长因子受体特异性抗体或其衍生物的糖尿病治疗
US20130059793A1 (en) * 2010-02-08 2013-03-07 Board Of Regents, The University Of Texas System Egf receptor mimicking peptides
EP3604339B1 (de) 2011-01-14 2021-03-10 The Regents Of The University Of California Therapeutische antikörper gegen das ror-1-protein und verfahren zur verwendung davon
CN109306010B (zh) * 2017-07-26 2022-07-19 石家庄以岭药业股份有限公司 表皮生长因子受体抗体及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0291636A1 (de) * 1983-11-07 1988-11-23 The Wistar Institute Von Anti-Idiotyp-Antikörpern induzierte Immunreaktion gegen Viren
US4699880A (en) * 1984-09-25 1987-10-13 Immunomedics, Inc. Method of producing monoclonal anti-idiotype antibody
US4918164A (en) * 1987-09-10 1990-04-17 Oncogen Tumor immunotherapy using anti-idiotypic antibodies
US5459061A (en) * 1990-01-26 1995-10-17 W. Alton Jones Cell Science Center, Inc. Hybridomas producing monoclonal antibodies which specifically bind to continuous epitope on the human EGF receptor and compete with EGF for binding to the EGF receptor
CA2082160C (en) * 1991-03-06 2003-05-06 Mary M. Bendig Humanised and chimeric monoclonal antibodies
US5344760A (en) * 1991-06-03 1994-09-06 Ciba Corning Diagnostics Corp. Method of cancer detection
DK0586002T3 (da) * 1992-08-18 2000-06-19 Centro Inmunologia Molecular Monoklonale antistoffer, som genkender epidermisvækstfaktor-receptoren, celler og fremgangsmåder heraf og præparater indeho

Also Published As

Publication number Publication date
ATE208403T1 (de) 2001-11-15
KR960040375A (ko) 1996-12-17
DE69616651D1 (de) 2001-12-13
NO962125L (no) 1996-11-27
CZ152596A3 (en) 1996-12-11
CA2177328A1 (en) 1996-11-27
NO962125D0 (no) 1996-05-24
AU710159B2 (en) 1999-09-16
PL314414A1 (en) 1996-12-09
MX9601930A (es) 1997-01-31
HUP9601392A3 (en) 2000-08-28
HU9601392D0 (en) 1996-07-29
CN1142505A (zh) 1997-02-12
HUP9601392A2 (en) 1997-03-28
US5969107A (en) 1999-10-19
SK67496A3 (en) 1996-12-04
CZ289357B6 (cs) 2002-01-16
JPH08325299A (ja) 1996-12-10
AU5242296A (en) 1996-12-05

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