ZA969412B - Tetracyclic 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them - Google Patents

Tetracyclic 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them

Info

Publication number: ZA969412B
Authority: ZA; South Africa
Prior art keywords: tetracyclic; preparation; pharmaceutical compositions; compositions containing; oxazine
Prior art date: 1995-11-09

Application number

ZA969412A

Other languages

English (en)

Inventor

Jean-Louis Peglion

Bertrand Goument

Jean-Christophe Harmange

Mark Millan

Valerie Audinot

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-09

Filing date

1996-11-08

Publication date

1997-06-02

1996-11-08 Application filed by Adir filed Critical Adir

1997-06-02 Publication of ZA969412B publication Critical patent/ZA969412B/xx

Links

150000004896 1,4-oxazines Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
YHWMFDLNZGIJSD-UHFFFAOYSA-N 2h-1,4-oxazine Chemical compound C1OC=CN=C1 YHWMFDLNZGIJSD-UHFFFAOYSA-N 0.000 abstract 1
BCHZICNRHXRCHY-UHFFFAOYSA-N 2h-oxazine Chemical compound N1OC=CC=C1 BCHZICNRHXRCHY-UHFFFAOYSA-N 0.000 abstract 1
ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ZA969412A 1995-11-09 1996-11-08 Tetracyclic 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them ZA969412B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9513270A FR2741074B1 (fr)	1995-11-09	1995-11-09	Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ZA969412B true ZA969412B (en)	1997-06-02

Family

ID=9484393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA969412A ZA969412B (en)	1995-11-09	1996-11-08	Tetracyclic 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them

Country Status (15)

Country	Link
US (1)	US5733908A (de)
EP (1)	EP0773223B1 (de)
JP (1)	JPH09169770A (de)
CN (1)	CN1059443C (de)
AT (1)	ATE198752T1 (de)
AU (1)	AU709192B2 (de)
CA (1)	CA2189731C (de)
DE (1)	DE69611594T2 (de)
ES (1)	ES2155585T3 (de)
FR (1)	FR2741074B1 (de)
GR (1)	GR3035432T3 (de)
NO (1)	NO308132B1 (de)
NZ (1)	NZ299725A (de)
PT (1)	PT773223E (de)
ZA (1)	ZA969412B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9810876D0 (en)	1998-05-20	1998-07-22	Smithkline Beecham Plc	Compounds
SK4782001A3 (en)	1998-10-08	2001-11-06	Smithkline Beecham Plc	Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
BRPI0409492A (pt) *	2003-04-18	2006-05-02	Pharmacia & Up John Company Ll	terapias de combinação
FR2906249B1 (fr)	2006-09-26	2008-12-19	Servier Lab	Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3583307D1 (en)	1984-05-10	1991-08-01	Ciba Geigy Ag	Benzo-(pyrano und thiopyrano)-pyridine.
US4792548A (en) *	1986-05-21	1988-12-20	Warner-Lambert Company	Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use
WO1993024471A1 (en)	1992-06-02	1993-12-09	Whitby Research, Inc.	Substituted naphthoxazines useful as dopaminergics
WO1994022495A1 (en) *	1993-03-31	1994-10-13	The Trustees Of The University Of Pennsylvania	Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
FR2721027B1 (fr) *	1994-06-08	1996-07-19	Adir	Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.

1995
- 1995-11-09 FR FR9513270A patent/FR2741074B1/fr not_active Expired - Fee Related
1996
- 1996-11-05 NO NO964672A patent/NO308132B1/no unknown
- 1996-11-06 CA CA002189731A patent/CA2189731C/fr not_active Expired - Fee Related
- 1996-11-07 ES ES96402366T patent/ES2155585T3/es not_active Expired - Lifetime
- 1996-11-07 PT PT96402366T patent/PT773223E/pt unknown
- 1996-11-07 AT AT96402366T patent/ATE198752T1/de not_active IP Right Cessation
- 1996-11-07 JP JP8295025A patent/JPH09169770A/ja active Pending
- 1996-11-07 DE DE69611594T patent/DE69611594T2/de not_active Expired - Fee Related
- 1996-11-07 EP EP96402366A patent/EP0773223B1/de not_active Expired - Lifetime
- 1996-11-07 AU AU71704/96A patent/AU709192B2/en not_active Ceased
- 1996-11-08 CN CN96114534A patent/CN1059443C/zh not_active Expired - Fee Related
- 1996-11-08 NZ NZ299725A patent/NZ299725A/en unknown
- 1996-11-08 ZA ZA969412A patent/ZA969412B/xx unknown
- 1996-11-08 US US08/745,212 patent/US5733908A/en not_active Expired - Fee Related
2001
- 2001-02-20 GR GR20010400263T patent/GR3035432T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1156147A (zh)	1997-08-06
CN1059443C (zh)	2000-12-13
EP0773223B1 (de)	2001-01-17
DE69611594T2 (de)	2001-08-09
CA2189731C (fr)	2002-04-09
NO964672D0 (no)	1996-11-05
ES2155585T3 (es)	2001-05-16
ATE198752T1 (de)	2001-02-15
JPH09169770A (ja)	1997-06-30
PT773223E (pt)	2001-06-29
NZ299725A (en)	1997-11-24
NO964672L (no)	1997-05-12
NO308132B1 (no)	2000-07-31
FR2741074B1 (fr)	1997-12-19
AU7170496A (en)	1997-05-15
FR2741074A1 (fr)	1997-05-16
EP0773223A1 (de)	1997-05-14
DE69611594D1 (de)	2001-02-22
AU709192B2 (en)	1999-08-26
GR3035432T3 (en)	2001-05-31
CA2189731A1 (fr)	1997-05-10
US5733908A (en)	1998-03-31

Similar Documents

Publication	Publication Date	Title
ES8306141A1 (es)	1983-05-01	Un procedimiento para la produccion de un derivado de carbostirilo
HU9700992D0 (en)	1997-07-28	New 3-(piperid-4-yl)1,2-benzisoxazole and 3-(piperazin-4-yl)-1,2-benzisoxazole compounds, process for their preparation and pharmaceutical compositions containing them
HUT59377A (en)	1992-05-28	Process for producing drugs containing new aromatic rings
DK0388309T3 (da)	1994-04-11	Nye derivater af 1H,3H-pyrrolo(1,2-c)thiazol-7-carboxamid, deres fremstilling og farmaceutiske præparater med indhold deraf
HU9400671D0 (en)	1994-06-28	Benzoxazine derivatives and process for producing them and pharmaceutical compositions containing them
GR3035432T3 (en)	2001-05-31	Tetracyclic 1,4-oxazine compounds, process for their preparation and pharmaceutical compositions containing them
DK0769296T3 (da)	2001-10-22	Anvendelse af et natrium- eller lysiniumsalt af crotonsyreamidderivater til fremstilling af et lægemiddel til behandling af cancer
ES2069065T3 (es)	1995-05-01	Nuevo derivado de hidroxilamina.
ES8305359A1 (es)	1983-04-01	Un procedimiento para la preparacion de benzamitas sustituidas.
ATE229513T1 (de)	2002-12-15	Disubstituierte trans-3,4,4a,5,6,10b-hexahydro-2h-napht(1,2-b)- ,4-oxazine, verfahren zu deren herstellung und diese enthaltende pharmazeutigsche zusammensetzungen
ATE191483T1 (de)	2000-04-15	Trizyklische oximether, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ZA954738B (en)	1996-01-26	Tetracyclic piperidine and 1,4-oxazine compounds a process for their preparation and pharmaceutical compositions containing them
IL102702A (en)	1997-04-15	OPTICALLY ACTIVE g-HALO- 2-AMINOALKANECARBOXYLIC ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE FOR THE PREPARATION OF OPTICALLY ACTIVE PHOSPHORUS-CONTAINING a-AMINO ACIDS
TW349949B (en)	1999-01-11	New imidazole derivatives, preparation process, intermediates obtained, use as medicaments, pharmaceutical compositions and new use
ATE200780T1 (de)	2001-05-15	Aminoalkyl benzothiazolinone, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten
AU4930797A (en)	1998-07-02	New ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them
MX9707911A (es)	1998-07-31	Derivados de amina 1-[w-(3,4-dihidro-2-naftalenil)alquil]- ciclica, proceso para su preparacion y composiciones farmaceuticas que contienen los mismos.