ZA972971B - Method for gene transfer to the central nervous system. - Google Patents

Method for gene transfer to the central nervous system.

Info

Publication number
ZA972971B
ZA972971B ZA9702971A ZA972971A ZA972971B ZA 972971 B ZA972971 B ZA 972971B ZA 9702971 A ZA9702971 A ZA 9702971A ZA 972971 A ZA972971 A ZA 972971A ZA 972971 B ZA972971 B ZA 972971B
Authority
ZA
South Africa
Prior art keywords
cells
nervous system
central nervous
gene transfer
producer cells
Prior art date
Application number
ZA9702971A
Other languages
English (en)
Inventor
Bruce Cherksey
Louis R Bucalo
Original Assignee
Univ New York Medical Ct
Theracell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York Medical Ct, Theracell Inc filed Critical Univ New York Medical Ct
Publication of ZA972971B publication Critical patent/ZA972971B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ZA9702971A 1996-04-08 1997-04-08 Method for gene transfer to the central nervous system. ZA972971B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/629,308 US6210664B1 (en) 1996-04-08 1996-04-08 Method for gene transfer to the central nervous system

Publications (1)

Publication Number Publication Date
ZA972971B true ZA972971B (en) 1997-11-03

Family

ID=24522456

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702971A ZA972971B (en) 1996-04-08 1997-04-08 Method for gene transfer to the central nervous system.

Country Status (13)

Country Link
US (2) US6210664B1 (fr)
EP (1) EP0927043B8 (fr)
JP (2) JP2000508641A (fr)
AT (1) ATE347903T1 (fr)
AU (1) AU724537C (fr)
CA (1) CA2251232C (fr)
DE (1) DE69737101T2 (fr)
DK (1) DK0927043T3 (fr)
ES (1) ES2277356T3 (fr)
PT (1) PT927043E (fr)
TW (1) TWI222870B (fr)
WO (1) WO1997037684A1 (fr)
ZA (1) ZA972971B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210664B1 (en) * 1996-04-08 2001-04-03 New York University Medical Center Method for gene transfer to the central nervous system
CA2647246C (fr) * 2006-03-30 2015-06-23 Research Foundation Of City University Of New York Procedes de stimulation de regeneration neuronale faisant intervenir l'inhibiteur secretoire de la protease du leucocyte (slpi)
KR20260007295A (ko) 2018-05-24 2026-01-13 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치
MX2020012459A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
EP3803866A4 (fr) 2018-05-24 2022-03-16 Nureva Inc. Procédé, appareil et supports lisibles par ordinateur pour gérer des sources sonores semi-constantes (persistantes) dans des zones de capture/foyer de microphones
BR112023022439A2 (pt) 2021-04-26 2023-12-26 Celanese Eva Performance Polymers Llc Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE117375T1 (de) * 1987-09-11 1995-02-15 Whitehead Biomedical Inst Transduktionsveränderte fibroblasten und ihre anwendung.
US5650148A (en) * 1988-12-15 1997-07-22 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system
DE69133205T2 (de) * 1990-10-19 2003-12-11 New York University, New York Eine methode zur transplantation von zellen in das gehirn und ihre therapeutische verwendung
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
US5529774A (en) * 1991-08-13 1996-06-25 The Regents Of The University Of California In vivo transfer of the HSV-TK gene implanted retroviral producer cells
AU3586993A (en) * 1992-01-23 1993-09-01 New York University A method for transplanting cells into the brain and therapeutic uses therefor
AU688321B2 (en) * 1993-04-21 1998-03-12 Institut Pasteur Biocompatible implant for the expression and secretion in vivo of a therapeutic compound
SG48813A1 (en) * 1993-08-12 1998-05-18 Cytotherapeutics Inc Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US5688773A (en) * 1994-08-17 1997-11-18 The General Hospital Corporation Method of selectively destroying neoplastic cells
US6210664B1 (en) * 1996-04-08 2001-04-03 New York University Medical Center Method for gene transfer to the central nervous system

Also Published As

Publication number Publication date
DK0927043T3 (da) 2007-04-10
CA2251232A1 (fr) 1997-10-16
EP0927043A4 (fr) 2004-09-01
WO1997037684A1 (fr) 1997-10-16
ATE347903T1 (de) 2007-01-15
JP2000508641A (ja) 2000-07-11
US20010003585A1 (en) 2001-06-14
JP2004337176A (ja) 2004-12-02
AU724537B2 (en) 2000-09-21
AU724537C (en) 2001-07-19
AU2444997A (en) 1997-10-29
CA2251232C (fr) 2005-10-25
EP0927043B8 (fr) 2007-04-18
PT927043E (pt) 2007-03-30
TWI222870B (en) 2004-11-01
EP0927043A1 (fr) 1999-07-07
DE69737101D1 (de) 2007-01-25
HK1021801A1 (en) 2000-07-07
US6210664B1 (en) 2001-04-03
US6565845B2 (en) 2003-05-20
DE69737101T2 (de) 2007-05-31
EP0927043B1 (fr) 2006-12-13
ES2277356T3 (es) 2007-07-01

Similar Documents

Publication Publication Date Title
Devine Mesenchymal stem cells: will they have a role in the clinic?
Kim et al. Brain transplantation of human neural stem cells transduced with tyrosine hydroxylase and GTP cyclohydrolase 1 provides functional improvement in animal models of Parkinson disease
Heath Cells for tissue engineering
EP1007630A4 (fr) Lignees de cellules tueuses naturelles et procedes d'utilisation
GR3036216T3 (en) Liver reserve cells.
ATE368103T1 (de) Isolierung, vermehrung und gezielte differenzierung von zäugetierstammzellen des zentralnervensystems
CA2407505A1 (fr) Cellules hepatocytes de lignee derivees de cellules souches pluripotentielles
SE0201328D0 (sv) Hematopoietic differentiation of human embryonic stem cells
CA2402299A1 (fr) Culture de cellules souches embryonnaires de primates exempte de serum
IL87196A (en) Serum free medium for the growthof insect cells and expressionof products thereby
WO1997012960A3 (fr) Support solide de culture de cellules et en particulier de cellules hepatiques, reacteur biologique utilisant ledit support et leur emploi dans un systeme de foie bio-artificiel
ATE297987T1 (de) Bedingte immortalisierung von zellen
Kasai et al. Cancer stem cells converted from pluripotent stem cells and the cancerous niche
Yoshida et al. Morphology and increased growth rate of atherosclerotic intimal smooth-muscle cells
ZA972971B (en) Method for gene transfer to the central nervous system.
EP1666589A1 (fr) Procede de production de lymphocytes cytotoxiques
IL137304A (en) Expanded and genetically modified populations of human hematopoietic stem cells
Dartsch et al. Human vascular smooth muscle cells in culture: growth characteristics and protein pattern by use of serum-free media supplements.
Glick et al. DNA-induced pigment production in a hamster cell line
DE69635513D1 (de) Menschliche pancreas zellinien: entwicklungen und anwendungen
Merrill Clonal derivation of a rat muscle cell strain that forms contraction-competent myotubes
Cossu et al. Similar glycopeptides in normal chondroblasts and in Rous sarcoma virus-transformed fibroblasts.
Karikusa et al. The restoration of the functions of serially passaged calf hepatocytes by spheroid formation
DE69737597D1 (de) Vektoren zur inhibierung von viralem und tumorwachstum
IL69928A (en) Hydrogen uptake gene cosmids,process of constructing same and use thereof