ZA974538B - Novel pyrrole derivatives. - Google Patents
Novel pyrrole derivatives.Info
- Publication number
- ZA974538B ZA974538B ZA9704538A ZA974538A ZA974538B ZA 974538 B ZA974538 B ZA 974538B ZA 9704538 A ZA9704538 A ZA 9704538A ZA 974538 A ZA974538 A ZA 974538A ZA 974538 B ZA974538 B ZA 974538B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrrole derivatives
- novel pyrrole
- novel
- derivatives
- pyrrole
- Prior art date
Links
- 150000003233 pyrroles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1869196P | 1996-05-30 | 1996-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA974538B true ZA974538B (en) | 1997-12-01 |
Family
ID=21789298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9704538A ZA974538B (en) | 1996-05-30 | 1997-05-23 | Novel pyrrole derivatives. |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US5952368A (de) |
| EP (1) | EP0906279B1 (de) |
| JP (1) | JP3142581B2 (de) |
| KR (1) | KR100303377B1 (de) |
| CN (1) | CN1225629A (de) |
| AR (1) | AR007297A1 (de) |
| AT (1) | ATE225333T1 (de) |
| AU (1) | AU717602B2 (de) |
| BR (1) | BR9709497A (de) |
| CA (1) | CA2256609C (de) |
| CO (1) | CO4960660A1 (de) |
| DE (1) | DE69716061T2 (de) |
| DK (1) | DK0906279T3 (de) |
| ES (1) | ES2182090T3 (de) |
| HR (1) | HRP970296A2 (de) |
| MA (1) | MA24346A1 (de) |
| PT (1) | PT906279E (de) |
| TR (1) | TR199802456T2 (de) |
| TW (1) | TW415946B (de) |
| WO (1) | WO1997046524A1 (de) |
| ZA (1) | ZA974538B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100793668B1 (ko) | 1999-12-08 | 2008-01-10 | 파마시아 코포레이션 | 강화된 생체이용률을 지닌 고체상 형태의 셀레콕시브 |
| AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
| CA2474702A1 (en) * | 2002-01-30 | 2003-08-07 | Tularik Inc | Heterocyclic arylsulfonamidobenzylic compounds |
| TWI372050B (en) * | 2003-07-03 | 2012-09-11 | Astex Therapeutics Ltd | (morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles |
| WO2005123671A1 (ja) * | 2004-06-22 | 2005-12-29 | Taisho Pharmaceutical Co., Ltd. | ピロール誘導体 |
| MX2007008008A (es) * | 2004-12-30 | 2007-11-12 | Astex Therapeutics Ltd | Compuestos de pirazol que modulan la actividad de las cinasas cdk, gsk y aurora. |
| US8399442B2 (en) * | 2005-12-30 | 2013-03-19 | Astex Therapeutics Limited | Pharmaceutical compounds |
| JP5523829B2 (ja) * | 2006-06-29 | 2014-06-18 | アステックス、セラピューティックス、リミテッド | 複合薬剤 |
| EP2043635A2 (de) * | 2006-06-29 | 2009-04-08 | Astex Therapeutics Limited | Pharmazeutische kombinationen |
| US10358408B2 (en) * | 2017-12-22 | 2019-07-23 | Polycarbon Industries, Inc. | Synthesis of azelaic acid |
| IL305573A (en) | 2021-03-15 | 2023-10-01 | Saul Yedgar | HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
| US4089969A (en) * | 1976-07-14 | 1978-05-16 | Syntex (U.S.A.) Inc. | 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof |
| ZA825227B (en) * | 1981-07-22 | 1984-03-28 | Syntex Inc | Substituted pyrrolidine cardiovascular system regulators antihypertensives |
| IL86462A (en) * | 1987-05-29 | 1992-12-01 | Fujisawa Pharmaceutical Co | Alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same |
| US5622948A (en) * | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
-
1997
- 1997-05-21 EP EP97925931A patent/EP0906279B1/de not_active Expired - Lifetime
- 1997-05-21 DE DE69716061T patent/DE69716061T2/de not_active Expired - Fee Related
- 1997-05-21 AT AT97925931T patent/ATE225333T1/de not_active IP Right Cessation
- 1997-05-21 PT PT97925931T patent/PT906279E/pt unknown
- 1997-05-21 BR BR9709497A patent/BR9709497A/pt unknown
- 1997-05-21 ES ES97925931T patent/ES2182090T3/es not_active Expired - Lifetime
- 1997-05-21 TR TR1998/02456T patent/TR199802456T2/xx unknown
- 1997-05-21 DK DK97925931T patent/DK0906279T3/da active
- 1997-05-21 KR KR1019980709759A patent/KR100303377B1/ko not_active Expired - Fee Related
- 1997-05-21 CN CN97196566A patent/CN1225629A/zh active Pending
- 1997-05-21 AU AU30913/97A patent/AU717602B2/en not_active Ceased
- 1997-05-21 JP JP10500147A patent/JP3142581B2/ja not_active Expired - Fee Related
- 1997-05-21 WO PCT/EP1997/002587 patent/WO1997046524A1/en not_active Ceased
- 1997-05-21 CA CA002256609A patent/CA2256609C/en not_active Expired - Fee Related
- 1997-05-23 ZA ZA9704538A patent/ZA974538B/xx unknown
- 1997-05-27 AR ARP970102246A patent/AR007297A1/es not_active Application Discontinuation
- 1997-05-28 US US08/864,703 patent/US5952368A/en not_active Expired - Fee Related
- 1997-05-28 HR HR60/018,691A patent/HRP970296A2/xx not_active Application Discontinuation
- 1997-05-28 CO CO97029326A patent/CO4960660A1/es unknown
- 1997-05-29 TW TW086107344A patent/TW415946B/zh not_active IP Right Cessation
- 1997-05-30 MA MA24642A patent/MA24346A1/fr unknown
-
1999
- 1999-03-24 US US09/275,542 patent/US6136844A/en not_active Expired - Fee Related
- 1999-03-24 US US09/275,540 patent/US6127402A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69716061D1 (de) | 2002-11-07 |
| CA2256609C (en) | 2005-07-26 |
| AU3091397A (en) | 1998-01-05 |
| KR20000016191A (ko) | 2000-03-25 |
| TR199802456T2 (xx) | 1999-02-22 |
| ATE225333T1 (de) | 2002-10-15 |
| DE69716061T2 (de) | 2003-08-14 |
| TW415946B (en) | 2000-12-21 |
| PT906279E (pt) | 2003-02-28 |
| EP0906279B1 (de) | 2002-10-02 |
| HRP970296A2 (en) | 1998-04-30 |
| ES2182090T3 (es) | 2003-03-01 |
| AR007297A1 (es) | 1999-10-27 |
| US6127402A (en) | 2000-10-03 |
| BR9709497A (pt) | 1999-08-10 |
| KR100303377B1 (ko) | 2001-12-12 |
| DK0906279T3 (da) | 2003-02-03 |
| JP3142581B2 (ja) | 2001-03-07 |
| AU717602B2 (en) | 2000-03-30 |
| WO1997046524A1 (en) | 1997-12-11 |
| CA2256609A1 (en) | 1997-12-11 |
| CN1225629A (zh) | 1999-08-11 |
| EP0906279A1 (de) | 1999-04-07 |
| US6136844A (en) | 2000-10-24 |
| MA24346A1 (fr) | 1998-07-01 |
| CO4960660A1 (es) | 2000-09-25 |
| JPH11511755A (ja) | 1999-10-12 |
| US5952368A (en) | 1999-09-14 |
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