ZA977151B - Mannose-6-phosphate composition and its use in treating fibrotic disorders - Google Patents
Mannose-6-phosphate composition and its use in treating fibrotic disordersInfo
- Publication number
- ZA977151B ZA977151B ZA977151A ZA977151A ZA977151B ZA 977151 B ZA977151 B ZA 977151B ZA 977151 A ZA977151 A ZA 977151A ZA 977151 A ZA977151 A ZA 977151A ZA 977151 B ZA977151 B ZA 977151B
- Authority
- ZA
- South Africa
- Prior art keywords
- mannose
- fibrotic disorders
- phosphate composition
- treating fibrotic
- phosphate
- Prior art date
Links
- NBSCHQHZLSJFNQ-QTVWNMPRSA-N D-Mannose-6-phosphate Chemical compound OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O NBSCHQHZLSJFNQ-QTVWNMPRSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000003176 fibrotic effect Effects 0.000 title 1
- 239000000725 suspension Substances 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 238000010979 pH adjustment Methods 0.000 abstract 1
- 230000036573 scar formation Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9616896.8A GB9616896D0 (en) | 1996-08-12 | 1996-08-12 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA977151B true ZA977151B (en) | 1999-02-11 |
Family
ID=10798358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA977151A ZA977151B (en) | 1996-08-12 | 1997-08-11 | Mannose-6-phosphate composition and its use in treating fibrotic disorders |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0921806B1 (de) |
| JP (2) | JP4971534B2 (de) |
| AT (1) | ATE249225T1 (de) |
| AU (1) | AU721224B2 (de) |
| CA (1) | CA2261988C (de) |
| DE (1) | DE69724798T2 (de) |
| DK (1) | DK0921806T3 (de) |
| ES (1) | ES2206737T3 (de) |
| GB (1) | GB9616896D0 (de) |
| PT (1) | PT921806E (de) |
| WO (1) | WO1998006406A1 (de) |
| ZA (1) | ZA977151B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9616896D0 (en) * | 1996-08-12 | 1996-09-25 | British Tech Group | Pharmaceutical compositions |
| WO2004031379A1 (en) * | 2002-10-01 | 2004-04-15 | Unilever N.V. | Proteins having polysaccharidase activity |
| US9517023B2 (en) | 2009-06-01 | 2016-12-13 | Profusa, Inc. | Method and system for directing a localized biological response to an implant |
| GB0910078D0 (en) | 2009-06-11 | 2009-07-22 | Renovo Ltd | Uses of mannose-6-phosphate |
| GB0916333D0 (en) | 2009-09-17 | 2009-10-28 | Renovo Ltd | Improvement of tendon repair |
| US10010272B2 (en) | 2010-05-27 | 2018-07-03 | Profusa, Inc. | Tissue-integrating electronic apparatus |
| WO2012048150A1 (en) | 2010-10-06 | 2012-04-12 | Profusa, Inc. | Tissue-integrating sensors |
| WO2014158988A1 (en) | 2013-03-14 | 2014-10-02 | Profusa, Inc. | Method and device for correcting optical signals |
| US10219729B2 (en) | 2013-06-06 | 2019-03-05 | Profusa, Inc. | Apparatus and methods for detecting optical signals from implanted sensors |
| WO2018119400A1 (en) | 2016-12-22 | 2018-06-28 | Profusa, Inc. | System and single-channel luminescent sensor for and method of determining analyte value |
| GB201904469D0 (en) * | 2019-03-29 | 2019-05-15 | Givaudan Sa | Cosmetic composition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5244651A (en) * | 1991-09-04 | 1993-09-14 | Kao Corporation | Method of desensitizing hypersensitive dentin |
| GB9205800D0 (en) * | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
| GB9616896D0 (en) * | 1996-08-12 | 1996-09-25 | British Tech Group | Pharmaceutical compositions |
-
1996
- 1996-08-12 GB GBGB9616896.8A patent/GB9616896D0/en active Pending
-
1997
- 1997-07-31 DE DE69724798T patent/DE69724798T2/de not_active Expired - Lifetime
- 1997-07-31 DK DK97934624T patent/DK0921806T3/da active
- 1997-07-31 AT AT97934624T patent/ATE249225T1/de active
- 1997-07-31 JP JP50947298A patent/JP4971534B2/ja not_active Expired - Fee Related
- 1997-07-31 CA CA002261988A patent/CA2261988C/en not_active Expired - Fee Related
- 1997-07-31 AU AU37769/97A patent/AU721224B2/en not_active Ceased
- 1997-07-31 EP EP97934624A patent/EP0921806B1/de not_active Expired - Lifetime
- 1997-07-31 ES ES97934624T patent/ES2206737T3/es not_active Expired - Lifetime
- 1997-07-31 WO PCT/GB1997/002076 patent/WO1998006406A1/en not_active Ceased
- 1997-07-31 PT PT97934624T patent/PT921806E/pt unknown
- 1997-08-11 ZA ZA977151A patent/ZA977151B/xx unknown
-
2009
- 2009-05-29 JP JP2009129987A patent/JP2009221220A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000516603A (ja) | 2000-12-12 |
| JP4971534B2 (ja) | 2012-07-11 |
| ATE249225T1 (de) | 2003-09-15 |
| DE69724798T2 (de) | 2004-07-15 |
| CA2261988C (en) | 2006-11-07 |
| DK0921806T3 (da) | 2003-12-08 |
| CA2261988A1 (en) | 1998-02-19 |
| AU721224B2 (en) | 2000-06-29 |
| JP2009221220A (ja) | 2009-10-01 |
| AU3776997A (en) | 1998-03-06 |
| PT921806E (pt) | 2003-12-31 |
| WO1998006406A1 (en) | 1998-02-19 |
| EP0921806A1 (de) | 1999-06-16 |
| ES2206737T3 (es) | 2004-05-16 |
| DE69724798D1 (de) | 2003-10-16 |
| EP0921806B1 (de) | 2003-09-10 |
| GB9616896D0 (en) | 1996-09-25 |
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