ZA9781B - Resolution of galanthamine. - Google Patents

Resolution of galanthamine.

Info

Publication number: ZA9781B
Authority: ZA; South Africa
Prior art keywords: galanthamine; pct; date jul; enantiomerically; sec
Prior art date: 1996-01-04

Application number

ZA9700081A

Other languages

English (en)

Inventor

Peter David Tiffin

Original Assignee

Chiroscience Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-04

Filing date

1997-01-06

Publication date

1998-01-06

1997-01-06 Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd

1998-01-06 Publication of ZA9781B publication Critical patent/ZA9781B/xx

Links

ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title abstract 9
HPOIPOPJGBKXIR-UHFFFAOYSA-N 3,6-dimethoxy-10-methyl-galantham-1-ene Natural products O1C(C(=CC=2)OC)=C3C=2CN(C)CCC23C1CC(OC)C=C2 HPOIPOPJGBKXIR-UHFFFAOYSA-N 0.000 title abstract 4
LPCKPBWOSNVCEL-UHFFFAOYSA-N Chlidanthine Natural products O1C(C(=CC=2)O)=C3C=2CN(C)CCC23C1CC(OC)C=C2 LPCKPBWOSNVCEL-UHFFFAOYSA-N 0.000 title abstract 4
229960003980 galantamine Drugs 0.000 title abstract 4
BGLNUNCBNALFOZ-WMLDXEAASA-N galanthamine Natural products COc1ccc2CCCC[C@@]34C=CCC[C@@H]3Oc1c24 BGLNUNCBNALFOZ-WMLDXEAASA-N 0.000 title abstract 4
ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 title abstract 4
IYVSXSLYJLAZAT-NOLJZWGESA-N lycoramine Natural products CN1CC[C@@]23CC[C@H](O)C[C@@H]2Oc4cccc(C1)c34 IYVSXSLYJLAZAT-NOLJZWGESA-N 0.000 title abstract 4
238000000034 method Methods 0.000 abstract 2
238000002425 crystallisation Methods 0.000 abstract 1
230000008025 crystallization Effects 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Glass Compositions (AREA)
Apparatus For Radiation Diagnosis (AREA)

ZA9700081A 1996-01-04 1997-01-06 Resolution of galanthamine. ZA9781B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9600080.7A GB9600080D0 (en)	1996-01-04	1996-01-04	Resolution process

Publications (1)

Publication Number	Publication Date
ZA9781B true ZA9781B (en)	1998-01-06

Family

ID=10786571

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9700081A ZA9781B (en)	1996-01-04	1997-01-06	Resolution of galanthamine.

Country Status (12)

Country	Link
US (1)	US6087495A (de)
EP (1)	EP0880525B1 (de)
AT (1)	ATE227725T1 (de)
AU (1)	AU700997B2 (de)
CA (1)	CA2239814C (de)
DE (1)	DE69717076T2 (de)
DK (1)	DK0880525T3 (de)
ES (1)	ES2186862T3 (de)
GB (1)	GB9600080D0 (de)
PT (1)	PT880525E (de)
WO (1)	WO1997025330A1 (de)
ZA (1)	ZA9781B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2310926C (en) *	2000-04-03	2002-10-15	Janssen Pharmaceutica N.V.	A use of galantamine for the treatment of neuropsychiatric behaviour associated with alzheimer's disease
US20050142193A1 (en) *	2003-12-31	2005-06-30	Lijuan Tang	Galantamine formulations
US20050191349A1 (en) *	2003-12-31	2005-09-01	Garth Boehm	Galantamine formulations
WO2006013546A2 (en) *	2004-07-28	2006-02-09	Ranbaxy Laboratories Limited	Process for the preparation of pure galantamine
CN102050826B (zh) *	2010-12-21	2012-11-14	浙江工业大学	一种分离加兰他敏的方法
US9309334B2 (en)	2014-01-15	2016-04-12	Exxonmobil Chemical Patents Inc.	Propylene-based impact copolymers
US11370902B2 (en)	2017-09-11	2022-06-28	Exxonmobil Chemical Patents Inc.	Articles comprising polypropylene impact copolymers and methods of making the same
CN116157429A (zh)	2020-07-17	2023-05-23	埃克森美孚化学专利公司	具有低水平挥发性有机化合物的聚合物和制备此类聚合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5428159A (en) *	1994-04-08	1995-06-27	Ciba-Geigy Corporation	Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

1996
- 1996-01-04 GB GBGB9600080.7A patent/GB9600080D0/en active Pending
1997
- 1997-01-06 WO PCT/GB1997/000023 patent/WO1997025330A1/en not_active Ceased
- 1997-01-06 DE DE69717076T patent/DE69717076T2/de not_active Expired - Lifetime
- 1997-01-06 ES ES97900276T patent/ES2186862T3/es not_active Expired - Lifetime
- 1997-01-06 CA CA002239814A patent/CA2239814C/en not_active Expired - Lifetime
- 1997-01-06 EP EP97900276A patent/EP0880525B1/de not_active Expired - Lifetime
- 1997-01-06 PT PT97900276T patent/PT880525E/pt unknown
- 1997-01-06 ZA ZA9700081A patent/ZA9781B/xx unknown
- 1997-01-06 US US09/101,174 patent/US6087495A/en not_active Expired - Lifetime
- 1997-01-06 DK DK97900276T patent/DK0880525T3/da active
- 1997-01-06 AU AU13867/97A patent/AU700997B2/en not_active Expired
- 1997-01-06 AT AT97900276T patent/ATE227725T1/de active

Also Published As

Publication number	Publication date
WO1997025330A1 (en)	1997-07-17
CA2239814A1 (en)	1997-07-17
AU1386797A (en)	1997-08-01
EP0880525B1 (de)	2002-11-13
US6087495A (en)	2000-07-11
DE69717076D1 (de)	2002-12-19
ATE227725T1 (de)	2002-11-15
GB9600080D0 (en)	1996-03-06
PT880525E (pt)	2003-03-31
CA2239814C (en)	2006-08-29
DE69717076T2 (de)	2003-07-17
AU700997B2 (en)	1999-01-14
DK0880525T3 (da)	2003-03-03
EP0880525A1 (de)	1998-12-02
ES2186862T3 (es)	2003-05-16

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