ZA978203B - Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine. - Google Patents

Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine.

Info

Publication number
ZA978203B
ZA978203B ZA9708203A ZA978203A ZA978203B ZA 978203 B ZA978203 B ZA 978203B ZA 9708203 A ZA9708203 A ZA 9708203A ZA 978203 A ZA978203 A ZA 978203A ZA 978203 B ZA978203 B ZA 978203B
Authority
ZA
South Africa
Prior art keywords
benzeneethanamine
isomers
trifluoromethyl
alpha
methyl
Prior art date
Application number
ZA9708203A
Other languages
English (en)
Inventor
Vincenzo Cannata
Tiziano Ferrario
Barbara Galbiati
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Publication of ZA978203B publication Critical patent/ZA978203B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA9708203A 1997-04-28 1997-09-11 Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine. ZA978203B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97BO000252A IT1292885B1 (it) 1997-04-28 1997-04-28 Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina.

Publications (1)

Publication Number Publication Date
ZA978203B true ZA978203B (en) 1998-04-29

Family

ID=11342228

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9708203A ZA978203B (en) 1997-04-28 1997-09-11 Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine.

Country Status (12)

Country Link
US (1) US5808156A (fr)
EP (1) EP0875498A3 (fr)
JP (1) JPH10330330A (fr)
KR (1) KR19980079310A (fr)
AR (1) AR008700A1 (fr)
AU (1) AU3322097A (fr)
CA (1) CA2212203A1 (fr)
HU (1) HUP9701364A3 (fr)
IT (1) IT1292885B1 (fr)
PL (1) PL322542A1 (fr)
TW (1) TW389748B (fr)
ZA (1) ZA978203B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100108394A (ko) * 2007-12-21 2010-10-06 바스프 에스이 일단계 환원성 아민화 방법
US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
CN107111673B (zh) 2014-09-29 2021-03-23 周格尼克斯国际有限公司 控制药物分配的控制系统
WO2017112701A1 (fr) 2015-12-22 2017-06-29 Zogenix International Limited Analogues de fenfluramine résistant au métabolisme et procédés pour les utiliser
ES3024232T3 (en) * 2015-12-22 2025-06-04 Zogenix International Ltd Fenfluramine compositions and methods of preparing the same
SG11201900975XA (en) 2016-08-24 2019-03-28 Zogenix International Ltd Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
WO2019216919A1 (fr) 2018-05-11 2019-11-14 Zogenix International Limited Compositions et méthodes pour traiter la mort subite provoquée par la crise épileptique
EA202191079A1 (ru) 2018-11-19 2021-09-20 Зодженикс Интернэшнл Лимитед Способы лечения синдрома ретта с применением фенфлурамина
US11612574B2 (en) 2020-07-17 2023-03-28 Zogenix International Limited Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR104F (fr) * 1960-11-05
GB1413078A (en) * 1973-07-27 1975-11-05 Beecham Group Ltd Process for the production of plus-norfenfluramine and plus-fenfluramine and salts thereof
GB1413070A (en) * 1973-07-27 1975-11-05 Beecham Group Ltd Process for the production of - norfenfluramine and - fenfluramine and salts thereof
DE3819438A1 (de) * 1987-06-30 1989-01-19 Basf Ag Verfahren zur herstellung von optisch aktiven 1-arylethylaminen

Also Published As

Publication number Publication date
JPH10330330A (ja) 1998-12-15
HUP9701364A3 (en) 1999-07-28
AR008700A1 (es) 2000-02-09
PL322542A1 (en) 1998-11-09
ITBO970252A1 (it) 1998-10-29
KR19980079310A (ko) 1998-11-25
AU3322097A (en) 1998-11-05
EP0875498A2 (fr) 1998-11-04
TW389748B (en) 2000-05-11
HU9701364D0 (en) 1997-09-29
US5808156A (en) 1998-09-15
IT1292885B1 (it) 1999-02-11
MX9709301A (es) 1998-10-31
EP0875498A3 (fr) 2000-07-26
CA2212203A1 (fr) 1998-10-29
HUP9701364A2 (hu) 1999-04-28
ITBO970252A0 (it) 1997-04-28

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