ZA978203B - Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine. - Google Patents
Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine.Info
- Publication number
- ZA978203B ZA978203B ZA9708203A ZA978203A ZA978203B ZA 978203 B ZA978203 B ZA 978203B ZA 9708203 A ZA9708203 A ZA 9708203A ZA 978203 A ZA978203 A ZA 978203A ZA 978203 B ZA978203 B ZA 978203B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzeneethanamine
- isomers
- trifluoromethyl
- alpha
- methyl
- Prior art date
Links
- MLBHFBKZUPLWBD-ZETCQYMHSA-N (2S)-1-[3-(trifluoromethyl)phenyl]-2-propanamine Chemical compound C[C@H](N)CC1=CC=CC(C(F)(F)F)=C1 MLBHFBKZUPLWBD-ZETCQYMHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97BO000252A IT1292885B1 (it) | 1997-04-28 | 1997-04-28 | Processo per la produzione degli isomeri (r) ed (s)- alfa -metil-3- (trifluorometil)benzene-etanamina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA978203B true ZA978203B (en) | 1998-04-29 |
Family
ID=11342228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9708203A ZA978203B (en) | 1997-04-28 | 1997-09-11 | Process for the production of the isomers (R) and (S)-alpha-methyl-3-(trifluoromethyl) benzeneethanamine. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5808156A (fr) |
| EP (1) | EP0875498A3 (fr) |
| JP (1) | JPH10330330A (fr) |
| KR (1) | KR19980079310A (fr) |
| AR (1) | AR008700A1 (fr) |
| AU (1) | AU3322097A (fr) |
| CA (1) | CA2212203A1 (fr) |
| HU (1) | HUP9701364A3 (fr) |
| IT (1) | IT1292885B1 (fr) |
| PL (1) | PL322542A1 (fr) |
| TW (1) | TW389748B (fr) |
| ZA (1) | ZA978203B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100108394A (ko) * | 2007-12-21 | 2010-10-06 | 바스프 에스이 | 일단계 환원성 아민화 방법 |
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| CN107111673B (zh) | 2014-09-29 | 2021-03-23 | 周格尼克斯国际有限公司 | 控制药物分配的控制系统 |
| WO2017112701A1 (fr) | 2015-12-22 | 2017-06-29 | Zogenix International Limited | Analogues de fenfluramine résistant au métabolisme et procédés pour les utiliser |
| ES3024232T3 (en) * | 2015-12-22 | 2025-06-04 | Zogenix International Ltd | Fenfluramine compositions and methods of preparing the same |
| SG11201900975XA (en) | 2016-08-24 | 2019-03-28 | Zogenix International Ltd | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| WO2019216919A1 (fr) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions et méthodes pour traiter la mort subite provoquée par la crise épileptique |
| EA202191079A1 (ru) | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR104F (fr) * | 1960-11-05 | |||
| GB1413078A (en) * | 1973-07-27 | 1975-11-05 | Beecham Group Ltd | Process for the production of plus-norfenfluramine and plus-fenfluramine and salts thereof |
| GB1413070A (en) * | 1973-07-27 | 1975-11-05 | Beecham Group Ltd | Process for the production of - norfenfluramine and - fenfluramine and salts thereof |
| DE3819438A1 (de) * | 1987-06-30 | 1989-01-19 | Basf Ag | Verfahren zur herstellung von optisch aktiven 1-arylethylaminen |
-
1997
- 1997-04-28 IT IT97BO000252A patent/IT1292885B1/it active IP Right Grant
- 1997-07-31 US US08/904,338 patent/US5808156A/en not_active Expired - Fee Related
- 1997-07-31 EP EP97113220A patent/EP0875498A3/fr not_active Withdrawn
- 1997-08-01 CA CA002212203A patent/CA2212203A1/fr not_active Abandoned
- 1997-08-06 TW TW086111229A patent/TW389748B/zh active
- 1997-08-06 HU HU9701364A patent/HUP9701364A3/hu unknown
- 1997-08-07 AU AU33220/97A patent/AU3322097A/en not_active Abandoned
- 1997-08-08 KR KR1019970037964A patent/KR19980079310A/ko not_active Ceased
- 1997-09-11 ZA ZA9708203A patent/ZA978203B/xx unknown
- 1997-10-10 PL PL97322542A patent/PL322542A1/xx unknown
- 1997-11-26 AR ARP970105548A patent/AR008700A1/es unknown
-
1998
- 1998-04-20 JP JP10109697A patent/JPH10330330A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10330330A (ja) | 1998-12-15 |
| HUP9701364A3 (en) | 1999-07-28 |
| AR008700A1 (es) | 2000-02-09 |
| PL322542A1 (en) | 1998-11-09 |
| ITBO970252A1 (it) | 1998-10-29 |
| KR19980079310A (ko) | 1998-11-25 |
| AU3322097A (en) | 1998-11-05 |
| EP0875498A2 (fr) | 1998-11-04 |
| TW389748B (en) | 2000-05-11 |
| HU9701364D0 (en) | 1997-09-29 |
| US5808156A (en) | 1998-09-15 |
| IT1292885B1 (it) | 1999-02-11 |
| MX9709301A (es) | 1998-10-31 |
| EP0875498A3 (fr) | 2000-07-26 |
| CA2212203A1 (fr) | 1998-10-29 |
| HUP9701364A2 (hu) | 1999-04-28 |
| ITBO970252A0 (it) | 1997-04-28 |
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