ZA9811794B - Ace inhibitor-MMP inhibitor combinations. - Google Patents

Ace inhibitor-MMP inhibitor combinations.

Info

Publication number: ZA9811794B
Authority: ZA; South Africa
Prior art keywords: inhibitor; combinations; mmp; ace; ace inhibitor
Prior art date: 1997-12-23

Application number

ZA9811794A

Other languages

English (en)

Inventor

Jr Joseph Thomas Peterson

Milton Lethan Pressler

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-23

Filing date

1998-12-22

Publication date

1999-06-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22083543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9811794(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-12-22 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1999-06-29 Publication of ZA9811794B publication Critical patent/ZA9811794B/xx

Links

229940124761 MMP inhibitor Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA9811794A 1997-12-23 1998-12-22 Ace inhibitor-MMP inhibitor combinations. ZA9811794B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6859497P	1997-12-23	1997-12-23

Publications (1)

Publication Number	Publication Date
ZA9811794B true ZA9811794B (en)	1999-06-29

Family

ID=22083543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9811794A ZA9811794B (en)	1997-12-23	1998-12-22	Ace inhibitor-MMP inhibitor combinations.

Country Status (24)

Country	Link
US (1)	US6133304A (da)
EP (1)	EP1047450B1 (da)
JP (1)	JP2001526245A (da)
KR (1)	KR20010033473A (da)
AR (1)	AR015504A1 (da)
AT (1)	ATE225187T1 (da)
AU (1)	AU751701B2 (da)
BR (1)	BR9814422A (da)
CA (1)	CA2305436A1 (da)
CO (1)	CO4970775A1 (da)
DE (1)	DE69808518T2 (da)
DK (1)	DK1047450T3 (da)
ES (1)	ES2184340T3 (da)
HU (1)	HUP0100427A3 (da)
IL (1)	IL135428A0 (da)
IS (1)	IS5446A (da)
NO (1)	NO20003256L (da)
NZ (1)	NZ503962A (da)
PE (1)	PE20000065A1 (da)
PL (1)	PL341335A1 (da)
PT (1)	PT1047450E (da)
UY (1)	UY25321A1 (da)
WO (1)	WO1999032150A1 (da)
ZA (1)	ZA9811794B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1165530A2 (en) *	1999-03-03	2002-01-02	The Procter & Gamble Company	Dihetero-substituted metalloprotease inhibitors
US6376524B1 (en)	2000-06-21	2002-04-23	Sunesis Pharmaceuticals, Inc.	Triphenyl compounds as interleukin-4 antagonists
GB0100761D0 (en)	2001-01-11	2001-02-21	Biocompatibles Ltd	Drug delivery from stents
NZ539682A (en)	2001-01-29	2006-03-31	Dimensional Pharm Inc	Substituted indoles and their use as integrin antagonists
DE10125882B4 (de) *	2001-05-28	2007-03-29	Esparma Gmbh	Arzneimittel enthaltend Ambroxol, dessen Salze und/oder Prodrugs zusammen mit α-Liponsäure im Rahmen der Behandlung des Diabetes mellitus
JPWO2003015762A1 (ja) *	2001-08-20	2004-12-02	小野薬品工業株式会社	心不全治療剤
GB0212412D0 (en) *	2002-05-29	2002-07-10	Novartis Ag	Combination of organic compounds
US7071211B2 (en) *	2002-09-27	2006-07-04	Bausch & Lomb Inc.	Small organic molecules that increase the activity of gelatinase a in ocular cells
US7364719B2 (en) *	2002-10-04	2008-04-29	The United States Of America As Represented By The Department Of Health And Human Services	Vasoregulating compounds and methods of their use
EP1575511A4 (en) *	2002-11-07	2006-06-28	Us Gov Health & Human Serv	NEW TARGET FOR ANGIOGENESIS AND ANTI-ANGIOGENESIS THERAPY
US20040225077A1 (en)	2002-12-30	2004-11-11	Angiotech International Ag	Drug delivery from rapid gelling polymer composition
CA2534352A1 (en)	2003-08-08	2005-02-17	Arriva Pharmaceuticals, Inc.	Methods of protein production in yeast
JP2007511539A (ja) *	2003-11-14	2007-05-10	バクスター・インターナショナル・インコーポレイテッド	α１−抗トリプシン組成物およびこのような組成物を用いた処置方法
JP2007528409A (ja) *	2004-03-09	2007-10-11	アリバファーマシューティカルズ，インコーポレイテッド	プロテアーゼインヒビターの低用量吸入による慢性閉塞性肺疾患の処置
MX2007001337A (es) *	2004-08-02	2008-03-13	Genmedica Therapeutics Sl	Compuestos para inhibir amina-oxidasas que contienen cobre y usos de los mismos.
CN100367956C (zh) *	2006-08-29	2008-02-13	陈俊云	用于治疗高血压的药物
CN102159211A (zh) *	2008-06-20	2011-08-17	金尼医疗公司	用于治疗纤维化疾病或病症的组合物
WO2010011302A1 (en) *	2008-07-22	2010-01-28	Chdi, Inc.	Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
CA2774389A1 (en) *	2009-10-01	2011-04-07	Symphony Evolution, Inc.	Methods of treating aneurysmal dilatation, blood vessel wall weakness and specifically abdominal aortic and thoracic aneurysm using matrix metalloprotease-2 inhibitors
BR112014004741B1 (pt)	2011-08-30	2021-10-13	Chdi Foundation, Inc	Entidade química, seu uso e composição farmacêutica compreendendo a mesma
AU2012300246A1 (en)	2011-08-30	2014-03-06	Chdi Foundation, Inc.	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
WO2014210062A1 (en)	2013-06-26	2014-12-31	Stealth Peptides International, Inc.	Methods for the regulation of matrix metalloproteinase expression
AU2015289492B2 (en)	2014-07-17	2020-02-20	Chdi Foundation, Inc.	Methods and compositions for treating HIV-related disorders
US20190008828A1 (en)	2015-12-28	2019-01-10	The U.S.A., As Represented By The Secretary Department Of Health And Human Services	Methods for inhibiting human immunodeficiency virus (hiv) release from infected cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2147875C1 (ru) *	1990-05-11	2000-04-27	Пфайзер Инк.	Способ и композиция для снижения кровяного давления и лечения застойной сердечной недостаточности у млекопитающего
DE69628821T2 (de) *	1995-02-10	2004-05-06	G.D. Searle & Co., Skokie	Kombination von ace-hemmern mit aldosteronantagonisten zur behandlung der ventrikulären hypertrophie
ATE207891T1 (de) *	1996-05-17	2001-11-15	Warner Lambert Co	Biphenylsulfonamid matrix metalloproteinase inhibitoren
US5756545A (en) *	1997-04-21	1998-05-26	Warner-Lambert Company	Biphenysulfonamide matrix metal alloproteinase inhibitors

1998
- 1998-11-10 KR KR1020007006974A patent/KR20010033473A/ko not_active Ceased
- 1998-11-10 DK DK98959416T patent/DK1047450T3/da active
- 1998-11-10 HU HU0100427A patent/HUP0100427A3/hu unknown
- 1998-11-10 AU AU15220/99A patent/AU751701B2/en not_active Ceased
- 1998-11-10 US US09/485,253 patent/US6133304A/en not_active Expired - Fee Related
- 1998-11-10 BR BR9814422-7A patent/BR9814422A/pt not_active IP Right Cessation
- 1998-11-10 PL PL98341335A patent/PL341335A1/xx unknown
- 1998-11-10 EP EP98959416A patent/EP1047450B1/en not_active Expired - Lifetime
- 1998-11-10 AT AT98959416T patent/ATE225187T1/de not_active IP Right Cessation
- 1998-11-10 WO PCT/US1998/023993 patent/WO1999032150A1/en not_active Ceased
- 1998-11-10 ES ES98959416T patent/ES2184340T3/es not_active Expired - Lifetime
- 1998-11-10 CA CA002305436A patent/CA2305436A1/en not_active Abandoned
- 1998-11-10 IL IL13542898A patent/IL135428A0/xx unknown
- 1998-11-10 JP JP2000525140A patent/JP2001526245A/ja active Pending
- 1998-11-10 PT PT98959416T patent/PT1047450E/pt unknown
- 1998-11-10 DE DE69808518T patent/DE69808518T2/de not_active Expired - Fee Related
- 1998-11-10 NZ NZ503962A patent/NZ503962A/xx unknown
- 1998-12-22 PE PE1998001267A patent/PE20000065A1/es not_active Application Discontinuation
- 1998-12-22 UY UY25321A patent/UY25321A1/es unknown
- 1998-12-22 CO CO98076095A patent/CO4970775A1/es unknown
- 1998-12-22 ZA ZA9811794A patent/ZA9811794B/xx unknown
- 1998-12-22 AR ARP980106613A patent/AR015504A1/es not_active Application Discontinuation
2000
- 2000-04-14 IS IS5446A patent/IS5446A/is unknown
- 2000-06-22 NO NO20003256A patent/NO20003256L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20003256D0 (no)	2000-06-22
PE20000065A1 (es)	2000-02-11
US6133304A (en)	2000-10-17
IS5446A (is)	2000-04-14
PL341335A1 (en)	2001-04-09
AR015504A1 (es)	2001-05-02
EP1047450B1 (en)	2002-10-02
HUP0100427A3 (en)	2002-11-28
AU1522099A (en)	1999-07-12
DK1047450T3 (da)	2003-01-27
NO20003256L (no)	2000-06-22
DE69808518T2 (de)	2003-06-26
JP2001526245A (ja)	2001-12-18
HUP0100427A2 (hu)	2001-06-28
ES2184340T3 (es)	2003-04-01
BR9814422A (pt)	2000-10-10
AU751701B2 (en)	2002-08-22
CO4970775A1 (es)	2000-11-07
CA2305436A1 (en)	1999-07-01
IL135428A0 (en)	2001-05-20
UY25321A1 (es)	2004-07-30
DE69808518D1 (de)	2002-11-07
PT1047450E (pt)	2003-02-28
KR20010033473A (ko)	2001-04-25
ATE225187T1 (de)	2002-10-15
NZ503962A (en)	2002-03-28
WO1999032150A1 (en)	1999-07-01
EP1047450A1 (en)	2000-11-02

Publication	Publication Date	Title
ZA977969B (en)	1998-03-18	Reflux inhibitors.
ZA98376B (en)	1998-07-23	Sulfamide-metalloprotease inhibitors
GB2321641B (en)	2001-04-04	Sulfamide-metalloprotease inhibitors
IL131661A0 (en)	2001-01-28	Protease inhibitors
PL331338A1 (en)	1999-07-05	Thiosulphonamidic metaloprotease inhibitors
PL336589A1 (en)	2000-07-03	Serinic protease inhibitors
ZA988967B (en)	2000-04-03	Lactam metalloprotease inhibitors.
HUP0100427A3 (en)	2002-11-28	Ace inhibitor-mmp inhibitor combinations
IL132630A0 (en)	2001-03-19	Protease inhibitors
IL132629A0 (en)	2001-03-19	Protease inhibitors
IL132088A0 (en)	2001-03-19	Protease inhibitors
ZA981926B (en)	1999-09-06	Detergent--package combination.
ZA987058B (en)	2000-02-07	Substituted 4-benzoylpyrazoles.
ZA987055B (en)	2000-02-07	Substituted 4-benzoylpyrazoles.
EP1015438A4 (en)	2000-11-08	PROTEASE INHIBITORS
ZA977209B (en)	1998-02-20	Thrombin inhibitors.
ZA974779B (en)	1997-12-01	Thrombin inhibitors.
ZA983705B (en)	1999-11-01	Pregnan-3-ol-20-ones.
GB9815925D0 (en)	1998-09-23	HIV Intergrase inhibitors
ZA987B (en)	1999-07-02	Substituted 4-benzoylpyrazoles.
ZA992106B (en)	1999-09-30	Statin-MMP inhibitor combinations.
EP0975612A4 (en)	2001-06-13	PROTEASE INHIBITORS
ZA981309B (en)	1999-08-17	4-aminoalkoxy-1H-benzoimidazoles.
ZA983795B (en)	1999-11-05	Substituted 4-benzoyl-pyrazoles.
SI1047450T1 (en)	2002-12-31	Ace inhibitor-mmp inhibitor combinations