ZA98755B - Substituted hydroxy-anilino derivatives of cyclobutane-3,4-diones. - Google Patents

Substituted hydroxy-anilino derivatives of cyclobutane-3,4-diones.

Info

Publication number
ZA98755B
ZA98755B ZA9800755A ZA98755A ZA98755B ZA 98755 B ZA98755 B ZA 98755B ZA 9800755 A ZA9800755 A ZA 9800755A ZA 98755 A ZA98755 A ZA 98755A ZA 98755 B ZA98755 B ZA 98755B
Authority
ZA
South Africa
Prior art keywords
diones
cyclobutane
substituted hydroxy
anilino derivatives
anilino
Prior art date
Application number
ZA9800755A
Other languages
English (en)
Inventor
Dominick Anthony Quagliato
Edward Martin Matelan
Madelene Miyoko Antane
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA98755B publication Critical patent/ZA98755B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9800755A 1997-01-30 1998-01-29 Substituted hydroxy-anilino derivatives of cyclobutane-3,4-diones. ZA98755B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79281197A 1997-01-30 1997-01-30

Publications (1)

Publication Number Publication Date
ZA98755B true ZA98755B (en) 1999-07-29

Family

ID=25158141

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9800755A ZA98755B (en) 1997-01-30 1998-01-29 Substituted hydroxy-anilino derivatives of cyclobutane-3,4-diones.

Country Status (3)

Country Link
AU (1) AU6250298A (fr)
WO (1) WO1998033763A1 (fr)
ZA (1) ZA98755B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2341711A1 (fr) * 1998-08-28 2000-03-09 Smithkline Beecham Corporation Procede de preparation de 2-amino-5-cyanophenol
US6495576B2 (en) 2001-02-07 2002-12-17 Abbott Laboratories Aminal diones as potassium channel openers
US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
CN1289471C (zh) * 2001-04-16 2006-12-13 先灵公司 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮
US7132445B2 (en) 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
JP2005505595A (ja) 2001-10-12 2005-02-24 シェーリング　コーポレイション Ｃｘｃ−ケモカインレセプターアンタゴニストとしての３，４−二置換マレイミド化合物
US6878709B2 (en) 2002-01-04 2005-04-12 Schering Corporation 3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists
WO2003080053A1 (fr) 2002-03-18 2003-10-02 Schering Corporation Traitements combines pour maladies induites par la chimiokine
PE20040570A1 (es) 2002-10-09 2004-08-30 Pharmacopeia Drug Discovery Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocina
ES2308299T3 (es) 2003-12-19 2008-12-01 Schering Corp Tiadiazoles como ligandos de receptores de cxc-y cc-quimioquinas.
TW200530231A (en) 2003-12-22 2005-09-16 Schering Corp Isothiazole dioxides as CXC-and CC-chemokine receptor ligands
MX2008000367A (es) 2005-06-29 2008-03-07 Schering Corp Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos de receptor de quimiocina en la que dos cisternas son separadas por un solo aminoacido.
EP1912971A2 (fr) 2005-06-29 2008-04-23 Shering Corporation Oxadiazoles di-substitutees utilisees en tant que ligands des recepteurs des chimiokines cxc
ES2655942T3 (es) 2011-09-02 2018-02-22 Novartis Ag Sal de colina de un compuesto anti-inflamatorio de ciclobutenodiona sustituida

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354763A (en) * 1993-11-17 1994-10-11 American Home Products Corporation Substituted N-heteroaryl and N-aryl-1,2-diaminocyclobutene-3,4-diones
US5506252A (en) * 1993-11-17 1996-04-09 American Home Products Corporation Substituted N-heteroaryl and N-aryl-1,2-diaminocyclobutene-3,4-diones

Also Published As

Publication number Publication date
WO1998033763A1 (fr) 1998-08-06
AU6250298A (en) 1998-08-25

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