ZA989783B - Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents - Google Patents
Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agentsInfo
- Publication number
- ZA989783B ZA989783B ZA989783A ZA989783A ZA989783B ZA 989783 B ZA989783 B ZA 989783B ZA 989783 A ZA989783 A ZA 989783A ZA 989783 A ZA989783 A ZA 989783A ZA 989783 B ZA989783 B ZA 989783B
- Authority
- ZA
- South Africa
- Prior art keywords
- antibacterial agents
- novel
- substituted quinazolin
- diones useful
- diones
- Prior art date
Links
- -1 7-substituted quinazolin-2,4-diones Chemical class 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6355697P | 1997-10-28 | 1997-10-28 | |
| US9858898P | 1998-08-31 | 1998-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA989783B true ZA989783B (en) | 1999-04-28 |
Family
ID=26743531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA989783A ZA989783B (en) | 1997-10-28 | 1998-10-27 | Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6331538B1 (de) |
| EP (1) | EP1028950B1 (de) |
| AT (1) | ATE239000T1 (de) |
| AU (1) | AU9503998A (de) |
| DE (1) | DE69814135T2 (de) |
| DK (1) | DK1028950T3 (de) |
| ES (1) | ES2195397T3 (de) |
| PT (1) | PT1028950E (de) |
| SI (1) | SI1028950T1 (de) |
| WO (1) | WO1999021840A1 (de) |
| ZA (1) | ZA989783B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2349180A1 (en) * | 1999-01-13 | 2000-07-20 | Stephen Douglas Barrett | Anthranilic acid derivatives |
| SK10572002A3 (sk) * | 2000-01-24 | 2003-10-07 | Warner-Lambert Company | 3-Aminochinazolín-2,4-diónové antibakteriálne činidlá |
| US7105682B2 (en) * | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
| JP2004532876A (ja) | 2001-05-30 | 2004-10-28 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 抗菌剤 |
| EP1401830A2 (de) * | 2001-06-19 | 2004-03-31 | Warner-Lambert Company LLC | Chinazolindione als antibakterielle mittel |
| CA2473545A1 (en) | 2002-01-23 | 2003-07-31 | Warner-Lambert Company Llc | N-(4-substituted phenyl)-anthranilic acid hydroxamate esters |
| DOP2003000556A (es) | 2002-01-23 | 2003-10-31 | Warner Lambert Co | Esteres hidroxamato de acido n-(4-fenil-sustituido)-antranilico. |
| JP2007505096A (ja) * | 2003-09-12 | 2007-03-08 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | キノロン抗菌剤 |
| WO2005030131A2 (en) * | 2003-09-23 | 2005-04-07 | Replidyne, Inc | Bis-quinazoline compounds for the treatment of bacterial infections |
| JP4533391B2 (ja) | 2004-01-16 | 2010-09-01 | エフ．ホフマン−ラ ロシュ アーゲー | 中枢神経系疾患の処置のための５−ヒドロキシトリプタミンレセプター（５−ｈｔ）のモジュレーターとしての、１−ベンジル−５−ピペラジン−１−イル−３，４−ジヒドロ−１ｈ−キナゾリン−２−オン誘導体、ならびにそれぞれの１ｈ−ベンゾ（１，２，６）チアジアジン−２，２−ジオキシドおよび１，４−ジヒドロベンゾ（ｄ）（１，３）オキサジン−２−オン誘導体 |
| WO2006019965A2 (en) * | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7767687B2 (en) | 2004-12-13 | 2010-08-03 | Biogen Idec Ma Inc. | Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors |
| US7973022B2 (en) * | 2006-02-17 | 2011-07-05 | Idexx Laboratories, Inc. | Fluoroquinolone carboxylic acid salt compositions |
| WO2008061866A1 (en) * | 2006-11-20 | 2008-05-29 | Bayer Cropscience Sa | New benzamide derivatives |
| MX2011012343A (es) * | 2009-05-19 | 2011-12-14 | Dow Agrosciences Llc | Compuestos y metodos para controlar hongos. |
| EP2440204B1 (de) | 2009-06-12 | 2013-12-18 | Bristol-Myers Squibb Company | Nikotinamidverbindungen als kinasemodulatoren |
| WO2011031745A1 (en) * | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| WO2013076590A1 (en) * | 2011-11-23 | 2013-05-30 | Oxygen Healthcare Research Pvt. Ltd | Benzothiazine compounds as h3 receptor ligands |
| WO2017051251A1 (en) * | 2015-09-25 | 2017-03-30 | Ludwig Institute For Cancer Research Ltd | 3-hydroxy-quinazoline-2,4-dione derivatives and their use as nuclease modulators |
| JP7741100B2 (ja) | 2020-05-04 | 2025-09-17 | アムジェン インコーポレイテッド | ミエロイド細胞に発現するトリガー受容体２アゴニストとしての複素環化合物及び使用方法 |
| TW202208355A (zh) | 2020-05-04 | 2022-03-01 | 美商安進公司 | 作為骨髓細胞觸發受體2促效劑之雜環化合物及使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1068263B (de) | 1959-11-05 | |||
| US5155110A (en) * | 1987-10-27 | 1992-10-13 | Warner-Lambert Company | Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition |
| US5283248A (en) | 1989-11-21 | 1994-02-01 | Hoffmann-La Roche Inc. | Amino substituted pyrimido[1,6-2]benzimidazoles |
| JP3002507B2 (ja) | 1990-08-03 | 2000-01-24 | 大日本製薬株式会社 | 四環式化合物 |
-
1998
- 1998-09-23 DK DK98948473T patent/DK1028950T3/da active
- 1998-09-23 AU AU95039/98A patent/AU9503998A/en not_active Abandoned
- 1998-09-23 ES ES98948473T patent/ES2195397T3/es not_active Expired - Lifetime
- 1998-09-23 PT PT98948473T patent/PT1028950E/pt unknown
- 1998-09-23 SI SI9830412T patent/SI1028950T1/xx unknown
- 1998-09-23 US US09/508,796 patent/US6331538B1/en not_active Expired - Fee Related
- 1998-09-23 EP EP98948473A patent/EP1028950B1/de not_active Expired - Lifetime
- 1998-09-23 WO PCT/US1998/019877 patent/WO1999021840A1/en not_active Ceased
- 1998-09-23 AT AT98948473T patent/ATE239000T1/de not_active IP Right Cessation
- 1998-09-23 DE DE69814135T patent/DE69814135T2/de not_active Expired - Fee Related
- 1998-10-27 ZA ZA989783A patent/ZA989783B/xx unknown
-
2001
- 2001-10-04 US US09/971,343 patent/US6825199B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999021840A1 (en) | 1999-05-06 |
| EP1028950B1 (de) | 2003-05-02 |
| ATE239000T1 (de) | 2003-05-15 |
| EP1028950A1 (de) | 2000-08-23 |
| US6331538B1 (en) | 2001-12-18 |
| US6825199B2 (en) | 2004-11-30 |
| US20020115674A1 (en) | 2002-08-22 |
| AU9503998A (en) | 1999-05-17 |
| ES2195397T3 (es) | 2003-12-01 |
| DE69814135T2 (de) | 2004-04-01 |
| DK1028950T3 (da) | 2003-09-01 |
| SI1028950T1 (en) | 2003-08-31 |
| DE69814135D1 (de) | 2003-06-05 |
| PT1028950E (pt) | 2003-09-30 |
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