ZA991982B - Salts of keto acids and amine derivatives and their use for the preparation of medicaments. - Google Patents

Salts of keto acids and amine derivatives and their use for the preparation of medicaments.

Info

Publication number
ZA991982B
ZA991982B ZA9901982A ZA991982A ZA991982B ZA 991982 B ZA991982 B ZA 991982B ZA 9901982 A ZA9901982 A ZA 9901982A ZA 991982 A ZA991982 A ZA 991982A ZA 991982 B ZA991982 B ZA 991982B
Authority
ZA
South Africa
Prior art keywords
medicaments
salts
preparation
amine derivatives
keto acids
Prior art date
Application number
ZA9901982A
Other languages
English (en)
Inventor
Thierry Bouyssou
Serge Biosa
Pierre-Andre Settembre
Christian Jeanpetit
Original Assignee
Logeais Labor Jacques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Logeais Labor Jacques filed Critical Logeais Labor Jacques
Publication of ZA991982B publication Critical patent/ZA991982B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9901982A 1998-03-13 1999-03-11 Salts of keto acids and amine derivatives and their use for the preparation of medicaments. ZA991982B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9803155A FR2775901B1 (fr) 1998-03-13 1998-03-13 Sels de cetoacides et de derives amines, et leur utilisation pour la preparation de medicaments

Publications (1)

Publication Number Publication Date
ZA991982B true ZA991982B (en) 1999-11-23

Family

ID=9524054

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901982A ZA991982B (en) 1998-03-13 1999-03-11 Salts of keto acids and amine derivatives and their use for the preparation of medicaments.

Country Status (19)

Country Link
US (1) US6429229B1 (de)
EP (1) EP1061909B1 (de)
JP (1) JP2002506816A (de)
AR (1) AR014714A1 (de)
AT (1) ATE218335T1 (de)
AU (1) AU2733699A (de)
BR (1) BR9909651A (de)
DE (1) DE69901689T2 (de)
DK (1) DK1061909T3 (de)
DZ (1) DZ2743A1 (de)
EG (1) EG24397A (de)
ES (1) ES2177250T3 (de)
FR (1) FR2775901B1 (de)
MA (1) MA24775A1 (de)
PT (1) PT1061909E (de)
TN (1) TNSN99032A1 (de)
TW (1) TWI235059B (de)
WO (1) WO1999047134A1 (de)
ZA (1) ZA991982B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060128806A1 (en) * 1998-05-28 2006-06-15 Medical Research Institute Controlled release arginine alpha-ketoglutarate
EP1318801B1 (de) * 2000-09-19 2009-03-11 Dermal Therapy (Barbados) Inc. Topische analgetische zusammensetzungen enthaltend aliphatische polyamine und methoden für ihre verwendung
FR2822704B1 (fr) * 2001-03-29 2005-02-18 Chiesi Sa Sels de cetoacides et d'acides amines gastroresistants et leur utilisation pour la preparation de medicaments
US7122578B2 (en) * 2001-09-11 2006-10-17 Alain Martin Method and composition for treating mammalian diseases and injuries which cause pain, erythema, swelling, crusting, ischemia scarring and excess white blood cell infiltration
PL372183A1 (pl) * 2005-01-11 2006-07-24 Sgp & Sons Ab Preparat przeciwnowotworowy oraz zastosowanie preparatu przeciwnowotworowego
US20110105617A1 (en) * 2005-01-11 2011-05-05 Sgp & Sons Ab Method for treatment of neoplastic diseases with alpha-keto glutarate and/or salts thereof
JP5630750B2 (ja) * 2008-03-18 2014-11-26 国立大学法人 岡山大学 興奮性化学伝達調節剤およびそのスクリーニング法
FR2953719A1 (fr) * 2009-12-10 2011-06-17 Luc Cynober Nouvelles applications therapeutiques d'un complexe d'alpha-cetoglutarate et d'ornithine
LT2523669T (lt) * 2010-01-11 2017-04-25 Inotek Pharmaceuticals Corporation Akispūdžio mažinimo būdas, derinys ir rinkinys
PH12012501906A1 (en) 2010-03-26 2013-01-14 Inotek Pharmaceuticals Corp Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof
PT2807178T (pt) 2012-01-26 2017-08-08 Inotek Pharmaceuticals Corp Polimorfos anidros de nitrato de (2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo e seus processos de preparação
US20140187815A1 (en) * 2012-12-28 2014-07-03 Guoji Zhang Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1
NZ630759A (en) 2013-03-15 2017-07-28 Inotek Pharmaceuticals Corp Ophthalmic formulations comprising an a1 agonist
EP3062766A1 (de) * 2013-10-29 2016-09-07 L'Oreal, S.A. Verwendung von mono-ornithin-ketoglutarat (mokg)
CN106674057A (zh) * 2015-11-09 2017-05-17 江西乐维生物药业有限公司 L-精氨酸a-酮基异己酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3533M (fr) * 1964-03-05 1965-09-13 Logeais Labor Jacques Médicament pour le traitement des intoxications ammoniacales a base d'α-cétoglutarate de l (+) ornithine.
US4320146A (en) * 1978-03-17 1982-03-16 The Johns Hopkins University Treatment of hepatic and renal disorders with ornithine and arginine salts of branched chain keto acids
DE3438455A1 (de) * 1984-10-19 1986-06-26 Institut Dr. Ziegler, Bettingen L-lysin- und l-histidinpyruvat
US4957938A (en) * 1989-06-21 1990-09-18 Abbott Laboratories Nutritional formulation for the treatment of renal disease

Also Published As

Publication number Publication date
AU2733699A (en) 1999-10-11
BR9909651A (pt) 2000-11-21
EG24397A (en) 2009-04-27
ATE218335T1 (de) 2002-06-15
FR2775901A1 (fr) 1999-09-17
TWI235059B (en) 2005-07-01
AR014714A1 (es) 2001-03-28
JP2002506816A (ja) 2002-03-05
DE69901689T2 (de) 2003-01-30
FR2775901B1 (fr) 2000-07-21
EP1061909B1 (de) 2002-06-05
DK1061909T3 (da) 2002-09-23
PT1061909E (pt) 2002-11-29
US6429229B1 (en) 2002-08-06
MA24775A1 (fr) 1999-10-01
DZ2743A1 (fr) 2004-09-05
TNSN99032A1 (fr) 2005-11-10
ES2177250T3 (es) 2002-12-01
EP1061909A1 (de) 2000-12-27
HK1035856A1 (en) 2001-12-14
WO1999047134A1 (fr) 1999-09-23
DE69901689D1 (de) 2002-07-11

Similar Documents

Publication Publication Date Title
HUP0900587A3 (en) Stable salts of 3,3-diphenylpropylamines and preparation thereof
HRP980163B1 (en) Pharmaceutical composition for the oral administration of an n-piperidinopyrazole -3-carboxamide derivative, its salts and their solvates
HUP0004050A3 (en) Itraconazole exhibiting improved solubility, a method of preparing the same and pharmaceutical composition for oral administration comprising the same
SG78412A1 (en) Oxime derivatives and the use thereof as latent acids
HUP0203542A3 (en) 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
EP1216980A4 (de) Carbonsäurederivate und medikamente, die diese enthalten
PL356769A1 (en) Novel heterocyclic compounds and salts thereof and medicinal use of the same
HUP0101336A3 (en) Process for the preparation of perindopril and their pharmaceutically acceptable salts
HUP0102585A3 (en) Thienylazolylalcoxyethanamin derivatives preparation the same and their use as medicaments
ZA991982B (en) Salts of keto acids and amine derivatives and their use for the preparation of medicaments.
HUP0102602A3 (en) Diacylhydrazine derivatives, method for their preparation, their use and pharmaceutical compositions comprising thereof
HUP0002902A3 (en) 3-substituted 3,4 dyhydro-thieno[2,3-d]pyrimidine derivatives and their use for the preparation of pharmaceutical compositions
IL146579A0 (en) Process for the preparation of herbicidal derivatives
HU9502520D0 (en) Pharmaceutical use of substituted 4-phenyl-6-amino-nicotinic acid derivatives
PL343936A1 (en) Oral medicinal preparations with reproducible release of the active ingredient gatifloxacin or its pharmaceutically suitable salts or hydrates
HUP0102369A3 (en) Amino acid derivatives and drugs containing the same as the active ingredient
HUP0203611A3 (en) 14,15-beta-methylene substituted androgens and their use for preparation of the medicaments
HUP0202283A3 (en) Process for the preparation of basic antibiotic-inorganic acid addition salts and intermediate oxalates
HUP0004648A3 (en) 3-substituted tetrahydropyridopyrimidinone derivatives and their use for producing pharmaceutical compositions
AU6475100A (en) Novel anilide derivatives or salts thereof and drugs containing the same
HUP0103788A3 (en) Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives
HUP0103712A3 (en) Salts of paroxetine, process for their preparation and their pharmaceutical use
HUP0102124A3 (en) Process for preparing 2-acetylthio-3-phenyl-propionic acid and the salts thereof
SI1073673T1 (sl) Derivati oktahidro-6,10-diokso-6H-piridazino(1,2-a)(1,2)diazepin-1-karboksilne kisline, postopek za njihovo pripravo in njihova uporaba za pripravo terapevtsko aktivnih spojin
ZA98347B (en) Methods for the preparation of benzophenone derivatives