ZA992076B - Process for synthesizing substituted 2-benzo (b) Thiophenecarboxylic acids and salts thereof. - Google Patents
Process for synthesizing substituted 2-benzo (b) Thiophenecarboxylic acids and salts thereof.Info
- Publication number
- ZA992076B ZA992076B ZA9902076A ZA992076A ZA992076B ZA 992076 B ZA992076 B ZA 992076B ZA 9902076 A ZA9902076 A ZA 9902076A ZA 992076 A ZA992076 A ZA 992076A ZA 992076 B ZA992076 B ZA 992076B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzo
- salts
- substituted
- alkali metal
- synthesizing substituted
- Prior art date
Links
- DYSJMQABFPKAQM-UHFFFAOYSA-N 1-benzothiophene-2-carboxylic acid Chemical class C1=CC=C2SC(C(=O)O)=CC2=C1 DYSJMQABFPKAQM-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 230000002194 synthesizing effect Effects 0.000 title 1
- -1 2-benzo[b]thiophenecarboxylic acid compound Chemical class 0.000 abstract 3
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 abstract 2
- 239000003905 agrochemical Substances 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000006331 halo benzoyl group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/039,769 US5965749A (en) | 1998-03-16 | 1998-03-16 | Process for synthesizing substituted 2-benzo [b]thiophenecarboxylic acids and salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA992076B true ZA992076B (en) | 1999-09-27 |
Family
ID=21907259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9902076A ZA992076B (en) | 1998-03-16 | 1999-03-15 | Process for synthesizing substituted 2-benzo (b) Thiophenecarboxylic acids and salts thereof. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5965749A (de) |
| EP (1) | EP1064276B1 (de) |
| JP (1) | JP3450827B2 (de) |
| KR (1) | KR100648791B1 (de) |
| AT (1) | ATE233255T1 (de) |
| CA (1) | CA2324263A1 (de) |
| DE (1) | DE69905553T2 (de) |
| DK (1) | DK1064276T3 (de) |
| ES (1) | ES2193689T3 (de) |
| IL (1) | IL138423A0 (de) |
| TW (1) | TW515797B (de) |
| WO (1) | WO1999047510A2 (de) |
| ZA (1) | ZA992076B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960669B2 (en) * | 2003-09-10 | 2005-11-01 | Crompton Co./Cie | Utilization of phosphorus pentasulfide in thionylations using phase transfer catalysis |
| JP5929483B2 (ja) * | 2011-05-10 | 2016-06-08 | 住友化学株式会社 | 植物の生長を促進する方法 |
| JP5929482B2 (ja) | 2011-05-10 | 2016-06-08 | 住友化学株式会社 | 植物の生長を促進する方法 |
| US9955689B2 (en) | 2012-11-09 | 2018-05-01 | Sumitomo Chemical Company, Limited | Method for promoting plant growth |
| CN105254605B (zh) * | 2015-11-03 | 2017-03-15 | 江西仁明医药化工有限公司 | 3‑巯基香豆素的制备方法 |
| CN105254611B (zh) * | 2015-11-09 | 2017-10-31 | 江西仁明医药化工有限公司 | 苯并噻吩‑2‑羧酸的制备方法 |
| CN106432179A (zh) * | 2016-07-26 | 2017-02-22 | 江苏兢业制药有限公司 | 一种4‑氯‑1‑苯并噻吩‑2‑羧酸的制备方法 |
| CN115988685B (zh) * | 2022-12-26 | 2025-09-05 | 烟台宁远药业有限公司 | 卤素取代噻吩并吡啶化合物的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4863923A (en) | 1988-07-01 | 1989-09-05 | Eli Lilly And Company | Method of inhibiting superoxide release |
| JP3213822B2 (ja) * | 1991-08-12 | 2001-10-02 | イハラケミカル工業株式会社 | ベンゾ〔ｂ〕チオフェン−２−カルボン酸の製造法 |
| US5340833A (en) * | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
| US5298630A (en) * | 1992-06-03 | 1994-03-29 | Sumitomo Seika Chemicals Co., Ltd. | Processes for producing 2-substituted benzo[B]thiophene |
| MX9406411A (es) * | 1993-08-24 | 1997-08-30 | Uniroyal Chem Co Inc | Oxatiazinas conservadoras de madera. |
| DE4420921A1 (de) * | 1994-06-16 | 1995-12-21 | Bayer Ag | Verfahren zur Herstellung von Benzthiophenderivaten |
-
1998
- 1998-03-16 US US09/039,769 patent/US5965749A/en not_active Expired - Lifetime
-
1999
- 1999-03-01 CA CA002324263A patent/CA2324263A1/en not_active Abandoned
- 1999-03-01 ES ES99908577T patent/ES2193689T3/es not_active Expired - Lifetime
- 1999-03-01 IL IL13842399A patent/IL138423A0/xx not_active IP Right Cessation
- 1999-03-01 DK DK99908577T patent/DK1064276T3/da active
- 1999-03-01 DE DE69905553T patent/DE69905553T2/de not_active Expired - Lifetime
- 1999-03-01 AT AT99908577T patent/ATE233255T1/de active
- 1999-03-01 KR KR1020007010267A patent/KR100648791B1/ko not_active Expired - Fee Related
- 1999-03-01 EP EP99908577A patent/EP1064276B1/de not_active Expired - Lifetime
- 1999-03-01 JP JP2000536707A patent/JP3450827B2/ja not_active Expired - Fee Related
- 1999-03-01 WO PCT/US1999/004418 patent/WO1999047510A2/en not_active Ceased
- 1999-03-15 ZA ZA9902076A patent/ZA992076B/xx unknown
- 1999-03-20 TW TW088104072A patent/TW515797B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK1064276T3 (da) | 2003-06-23 |
| KR20010041952A (ko) | 2001-05-25 |
| WO1999047510A3 (en) | 1999-11-25 |
| WO1999047510A2 (en) | 1999-09-23 |
| ES2193689T3 (es) | 2003-11-01 |
| EP1064276A2 (de) | 2001-01-03 |
| DE69905553T2 (de) | 2003-11-20 |
| JP2002506860A (ja) | 2002-03-05 |
| US5965749A (en) | 1999-10-12 |
| DE69905553D1 (de) | 2003-04-03 |
| EP1064276B1 (de) | 2003-02-26 |
| IL138423A0 (en) | 2001-10-31 |
| KR100648791B1 (ko) | 2006-11-23 |
| ATE233255T1 (de) | 2003-03-15 |
| TW515797B (en) | 2003-01-01 |
| JP3450827B2 (ja) | 2003-09-29 |
| CA2324263A1 (en) | 1999-09-23 |
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