ZA992596B - Azabicyclic 5HT1 receptor ligands. - Google Patents
Azabicyclic 5HT1 receptor ligands.Info
- Publication number
- ZA992596B ZA992596B ZA9902596A ZA992596A ZA992596B ZA 992596 B ZA992596 B ZA 992596B ZA 9902596 A ZA9902596 A ZA 9902596A ZA 992596 A ZA992596 A ZA 992596A ZA 992596 B ZA992596 B ZA 992596B
- Authority
- ZA
- South Africa
- Prior art keywords
- azabicyclic
- receptor ligands
- ligands
- receptor
- Prior art date
Links
- 102000035038 5-HT1 receptors Human genes 0.000 title 1
- 108091005478 5-HT1 receptors Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8123798P | 1998-04-09 | 1998-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA992596B true ZA992596B (en) | 2000-10-08 |
Family
ID=22162936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9902596A ZA992596B (en) | 1998-04-09 | 1999-04-08 | Azabicyclic 5HT1 receptor ligands. |
Country Status (40)
| Country | Link |
|---|---|
| US (2) | US6525048B1 (cs) |
| EP (1) | EP1070065B1 (cs) |
| JP (1) | JP3496759B2 (cs) |
| KR (1) | KR100378931B1 (cs) |
| CN (1) | CN1117092C (cs) |
| AP (1) | AP1175A (cs) |
| AR (1) | AR015751A1 (cs) |
| AT (1) | ATE248838T1 (cs) |
| AU (1) | AU749254B2 (cs) |
| BG (1) | BG104915A (cs) |
| BR (1) | BR9909522A (cs) |
| CA (1) | CA2327782A1 (cs) |
| CO (1) | CO5080727A1 (cs) |
| CZ (1) | CZ20003684A3 (cs) |
| DE (1) | DE69910997T2 (cs) |
| DK (1) | DK1070065T3 (cs) |
| DZ (1) | DZ2756A1 (cs) |
| EA (1) | EA003400B1 (cs) |
| ES (1) | ES2204154T3 (cs) |
| HR (1) | HRP20000653A2 (cs) |
| HU (1) | HUP0102400A3 (cs) |
| ID (1) | ID26086A (cs) |
| IL (1) | IL138629A0 (cs) |
| IS (1) | IS5641A (cs) |
| MA (1) | MA26619A1 (cs) |
| MY (1) | MY133390A (cs) |
| NO (1) | NO20005004L (cs) |
| NZ (1) | NZ507010A (cs) |
| OA (1) | OA11496A (cs) |
| PA (1) | PA8469101A1 (cs) |
| PE (1) | PE20000413A1 (cs) |
| PL (1) | PL343408A1 (cs) |
| PT (1) | PT1070065E (cs) |
| SK (1) | SK14782000A3 (cs) |
| TN (1) | TNSN99056A1 (cs) |
| TR (1) | TR200002932T2 (cs) |
| TW (1) | TW555758B (cs) |
| WO (1) | WO1999052907A1 (cs) |
| YU (1) | YU59400A (cs) |
| ZA (1) | ZA992596B (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6231833B1 (en) * | 1999-08-05 | 2001-05-15 | Pfizer Inc | 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors |
| UA62015C2 (en) | 1998-12-28 | 2003-12-15 | Pfizer Prod Inc | Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants) |
| EA004101B1 (ru) | 1999-09-03 | 2003-12-25 | Эли Лилли Энд Компани | Применение селективных ингибиторов обратного захвата серотонина быстрого запуска для лечения половой дисфункции |
| GB2362826A (en) * | 2000-06-02 | 2001-12-05 | Lilly Co Eli | A pharmaceutical composition comprising a serotonin transport inhibitor and a serotonin recptor antagonist |
| DE60229123D1 (de) * | 2001-02-20 | 2008-11-13 | Dinan Timothy Gerard | Behandlung von fibromyalgie mit pindolol |
| JP3910627B2 (ja) * | 2003-03-12 | 2007-04-25 | ファイザー・プロダクツ・インク | ピリジルオキシメチルおよびベンゾイソオキサゾールのアザビシクロ環の誘導体 |
| JP2007519705A (ja) * | 2004-01-29 | 2007-07-19 | ファイザー・プロダクツ・インク | Cns障害を治療するための非定型抗精神病薬とアミノメチルピリジルオキシメチル/ベンゾイソオキサゾールアザビシクロ誘導体の組合せ |
| JP4559749B2 (ja) * | 2004-02-16 | 2010-10-13 | あすか製薬株式会社 | ピペラジニルピリジン誘導体 |
| AR049478A1 (es) | 2004-03-25 | 2006-08-09 | Solvay Pharm Bv | Un procedimiento para la preparacion de 3-amino-8-(1-piperazinil)-2h-1-benzopiran-2-ona. sales e hidratos y composiciones farmaceuticas. |
| AR048112A1 (es) * | 2004-03-25 | 2006-03-29 | Solvay Pharm Bv | Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor |
| JP2008503560A (ja) * | 2004-06-22 | 2008-02-07 | ファイザー・プロダクツ・インク | ジアザビシクロ系のヒスタミン−3受容体アンタゴニスト |
| EP2248524A3 (en) | 2004-08-25 | 2011-03-09 | Takeda Pharmaceutical Company Limited | Preventives/remedies for stress urinary incontinence and method of screening the same |
| WO2006027692A2 (en) * | 2004-09-10 | 2006-03-16 | Pfizer Products Inc. | Methods of treating cognitive disorders using pyridyloxymethyl and benzisoxazole azabicyclic derivatives |
| RU2417082C2 (ru) * | 2009-07-14 | 2011-04-27 | Учреждение Российской Академии Наук Институт Физиологически Активных Веществ Ран (Ифав Ран) | Средство для восстановления утраченной памяти в норме и патологии у пациентов всех возрастных групп на основе n, n'-замещенных 3, 7-диазабицикло[3.3.1]нонанов, фармацевтическая композиция на его основе и способ ее применения |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106849A (en) * | 1988-05-24 | 1992-04-21 | American Home Products Corporation | Use of aryl- and heteroaryl piperazinyl carboxamides in the treatment of various central nervous system disorders |
| MX19222A (es) * | 1989-01-23 | 1993-12-01 | Pfizer | Agentes ansioliticos bis-aza-biciclicos |
| US5157034A (en) * | 1991-02-27 | 1992-10-20 | Pfizer Inc. | Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines |
| US5565453A (en) * | 1991-09-25 | 1996-10-15 | Pfizer Inc. | Neuroleptic 2-substituted perhydro-1-h-pyrido[1,2-a]pyrazines |
| US5262428A (en) * | 1992-03-13 | 1993-11-16 | Wake Forest University | Biologically active tropane derivatives |
| WO1993025552A1 (en) * | 1992-06-16 | 1993-12-23 | Pfizer Inc. | Process and intermediates for bis-aza-bicyclic anxiolytic agents |
| GB9410512D0 (en) * | 1994-05-25 | 1994-07-13 | Smithkline Beecham Plc | Novel treatment |
| WO1996010570A1 (en) * | 1994-09-30 | 1996-04-11 | Pfizer Inc. | NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES |
| US5614523A (en) * | 1995-01-17 | 1997-03-25 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
-
1999
- 1999-03-17 PA PA19998469101A patent/PA8469101A1/es unknown
- 1999-03-18 BR BR9909522-0A patent/BR9909522A/pt not_active Application Discontinuation
- 1999-03-18 NZ NZ507010A patent/NZ507010A/en unknown
- 1999-03-18 AT AT99945686T patent/ATE248838T1/de not_active IP Right Cessation
- 1999-03-18 CZ CZ20003684A patent/CZ20003684A3/cs unknown
- 1999-03-18 DK DK99945686T patent/DK1070065T3/da active
- 1999-03-18 DE DE69910997T patent/DE69910997T2/de not_active Expired - Fee Related
- 1999-03-18 HR HR20000653A patent/HRP20000653A2/hr not_active Application Discontinuation
- 1999-03-18 ES ES99945686T patent/ES2204154T3/es not_active Expired - Lifetime
- 1999-03-18 HU HU0102400A patent/HUP0102400A3/hu unknown
- 1999-03-18 JP JP2000543464A patent/JP3496759B2/ja not_active Expired - Fee Related
- 1999-03-18 SK SK1478-2000A patent/SK14782000A3/sk unknown
- 1999-03-18 KR KR10-2000-7011167A patent/KR100378931B1/ko not_active Expired - Fee Related
- 1999-03-18 CA CA002327782A patent/CA2327782A1/en not_active Abandoned
- 1999-03-18 EA EA200000910A patent/EA003400B1/ru not_active IP Right Cessation
- 1999-03-18 IL IL13862999A patent/IL138629A0/xx unknown
- 1999-03-18 YU YU59400A patent/YU59400A/sh unknown
- 1999-03-18 WO PCT/IB1999/000457 patent/WO1999052907A1/en not_active Ceased
- 1999-03-18 EP EP99945686A patent/EP1070065B1/en not_active Expired - Lifetime
- 1999-03-18 AU AU32687/99A patent/AU749254B2/en not_active Ceased
- 1999-03-18 PL PL99343408A patent/PL343408A1/xx not_active Application Discontinuation
- 1999-03-18 TR TR2000/02932T patent/TR200002932T2/xx unknown
- 1999-03-18 CN CN99807195A patent/CN1117092C/zh not_active Expired - Fee Related
- 1999-03-18 ID IDW20002017A patent/ID26086A/id unknown
- 1999-03-18 PT PT99945686T patent/PT1070065E/pt unknown
- 1999-03-18 US US09/403,892 patent/US6525048B1/en not_active Expired - Fee Related
- 1999-04-02 TW TW088105301A patent/TW555758B/zh not_active IP Right Cessation
- 1999-04-05 PE PE1999000270A patent/PE20000413A1/es not_active Application Discontinuation
- 1999-04-07 MA MA25527A patent/MA26619A1/fr unknown
- 1999-04-07 DZ DZ990057A patent/DZ2756A1/xx active
- 1999-04-07 AR ARP990101572A patent/AR015751A1/es unknown
- 1999-04-07 MY MYPI99001344A patent/MY133390A/en unknown
- 1999-04-07 TN TNTNSN99056A patent/TNSN99056A1/fr unknown
- 1999-04-08 AP APAP/P/1999/001502A patent/AP1175A/en active
- 1999-04-08 ZA ZA9902596A patent/ZA992596B/xx unknown
- 1999-04-09 CO CO99021093A patent/CO5080727A1/es unknown
-
2000
- 2000-09-26 IS IS5641A patent/IS5641A/is unknown
- 2000-10-04 NO NO20005004A patent/NO20005004L/no not_active Application Discontinuation
- 2000-10-06 OA OA1200000273A patent/OA11496A/en unknown
- 2000-11-07 BG BG104915A patent/BG104915A/xx unknown
-
2003
- 2003-02-11 US US10/364,804 patent/US6887905B2/en not_active Expired - Fee Related
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