ZW5291A1 - Novel pyrido(2,3-f)(1,4)thiazepines and pyrido(3,2-b)(1,5)benzothiazepines - Google Patents

Novel pyrido(2,3-f)(1,4)thiazepines and pyrido(3,2-b)(1,5)benzothiazepines

Info

Publication number: ZW5291A1
Authority: ZW; Zimbabwe
Prior art keywords: pyrido; novel; thiazepines; benzothiazepines; compounds
Prior art date: 1990-05-03

Application number

ZW52/91A

Other languages

English (en)

Inventor

Jurgen Wustrow David

Harold Dodd John

Frederick Schwender Charles

Original Assignee

Ortho Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-03

Filing date

1991-05-02

Publication date

1993-01-06

1991-05-02 Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp

1993-01-06 Publication of ZW5291A1 publication Critical patent/ZW5291A1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Luminescent Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

ZW52/91A 1990-05-03 1991-05-02 Novel pyrido(2,3-f)(1,4)thiazepines and pyrido(3,2-b)(1,5)benzothiazepines ZW5291A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/518,351 US5075440A (en)	1990-05-03	1990-05-03	Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines

Publications (1)

Publication Number	Publication Date
ZW5291A1 true ZW5291A1 (en)	1993-01-06

Family

ID=24063558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZW52/91A ZW5291A1 (en)	1990-05-03	1991-05-02	Novel pyrido(2,3-f)(1,4)thiazepines and pyrido(3,2-b)(1,5)benzothiazepines

Country Status (25)

Country	Link
US (1)	US5075440A (ja)
EP (1)	EP0462696B1 (ja)
JP (1)	JP3296499B2 (ja)
KR (1)	KR100195345B1 (ja)
CN (2)	CN1034077C (ja)
AT (1)	ATE126231T1 (ja)
AU (1)	AU651580B2 (ja)
CA (1)	CA2041594C (ja)
DE (1)	DE69111915T2 (ja)
DK (1)	DK0462696T3 (ja)
ES (1)	ES2079570T3 (ja)
FI (1)	FI95912C (ja)
GR (1)	GR3017305T3 (ja)
HK (1)	HK51496A (ja)
HU (1)	HU218909B (ja)
IE (1)	IE68524B1 (ja)
IL (6)	IL120447A (ja)
MY (1)	MY106552A (ja)
NO (1)	NO179411C (ja)
NZ (1)	NZ237988A (ja)
PT (1)	PT97547B (ja)
TN (1)	TNSN91030A1 (ja)
TW (1)	TW218878B (ja)
ZA (1)	ZA913319B (ja)
ZW (1)	ZW5291A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1040097T3 (da) *	1997-12-18	2004-08-02	Abbott Lab	Stoffer, som åbner kaliumkanaler
US6265417B1 (en)	1997-12-18	2001-07-24	Abbott Laboratories	Potassium channel openers
US6593335B1 (en) *	1997-12-18	2003-07-15	Abbott Laboratories	Potassium channel openers
JPH11193289A (ja)	1997-12-26	1999-07-21	Suntory Ltd	ピロールスルホンアミド誘導体
US6482854B1 (en) *	1999-03-25	2002-11-19	Massachusetts Eye And Ear Infirmary	Glaucoma treatment
US7015212B1 (en)	1999-05-12	2006-03-21	The United States Of America As Represented By The Department Of Health And Human Services	Thiazepine inhibitors of HIV-1 integrase
JP2003502335A (ja) *	1999-06-14	2003-01-21	オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド	ジチエピノ［６，５−ｂ］ピリジンおよび関連組成物および方法
DK1200446T3 (da)	1999-07-12	2005-10-24	Ortho Mcneil Pharm Inc	Oxathiepino[6,5-b]dihydropyridiner og beslægtede forbindelser og fremgangsmåder
US6472530B1 (en)	1999-09-22	2002-10-29	Ortho-Mcneil Pharmaceutical, Inc.	Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods
CA2396962A1 (en) *	2000-01-12	2001-07-19	Ortho-Mcneil Pharmaceutical, Inc.	Benzosulfones and related compositions and methods
US6410552B1 (en)	2000-01-27	2002-06-25	Ortho-Mcneil Pharmaceutical, Inc.	Benzoether and related compositions and methods
JP2003528104A (ja)	2000-03-23	2003-09-24	オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド	チエピノ［３，２−ｂ］ジヒドロピリジンおよび関連組成物ならびに方法
JP2003535096A (ja)	2000-05-30	2003-11-25	オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド	ジヒドロピリジンソフトドラッグならびに関連する組成物及び方法
KR101233139B1 (ko)	2011-04-21	2013-02-21	주식회사 한서켐	라세믹 1,4-티아제핀 화합물의 분할 방법
US20160207893A1 (en) *	2014-12-30	2016-07-21	Myotherix, Inc.	Novel calcium modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1587128A (en) *	1977-04-07	1981-04-01	Hexachimie	Benzothiazepine derivatives
US4285955A (en) *	1978-10-31	1981-08-25	Bayer Aktiengesellschaft	1,4-Dihydropyridinecarboxylic acids
NZ201395A (en) *	1981-07-30	1987-02-20	Bayer Ag	Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
FR2511683A1 (fr) *	1981-08-20	1983-02-25	Hexachimie	Nouveaux derives de la pyrido (2,3-b) benzothiazepine(1,5) substituee en 5 par une carboxypiperazine, leur procede de preparation, leur application en therapeutique
EP0225175A3 (en) *	1985-11-28	1988-12-28	FISONS plc	Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof

1990
- 1990-05-03 US US07/518,351 patent/US5075440A/en not_active Expired - Lifetime
1991
- 1991-04-29 IL IL12044797A patent/IL120447A/xx not_active IP Right Cessation
- 1991-04-29 IL IL12044697A patent/IL120446A0/xx unknown
- 1991-04-29 IL IL12704791A patent/IL127047A/xx not_active IP Right Cessation
- 1991-04-29 IL IL12704798A patent/IL127047A0/xx unknown
- 1991-04-29 IL IL12044691A patent/IL120446A/xx not_active IP Right Cessation
- 1991-04-29 IL IL97999A patent/IL97999A/xx not_active IP Right Cessation
- 1991-04-29 NZ NZ237988A patent/NZ237988A/xx unknown
- 1991-05-01 CA CA002041594A patent/CA2041594C/en not_active Expired - Fee Related
- 1991-05-02 IE IE148891A patent/IE68524B1/en not_active IP Right Cessation
- 1991-05-02 FI FI912124A patent/FI95912C/fi active
- 1991-05-02 ZW ZW52/91A patent/ZW5291A1/xx unknown
- 1991-05-02 ES ES91303970T patent/ES2079570T3/es not_active Expired - Lifetime
- 1991-05-02 HU HU476/91A patent/HU218909B/hu not_active IP Right Cessation
- 1991-05-02 ZA ZA913319A patent/ZA913319B/xx unknown
- 1991-05-02 AU AU76354/91A patent/AU651580B2/en not_active Ceased
- 1991-05-02 EP EP91303970A patent/EP0462696B1/en not_active Expired - Lifetime
- 1991-05-02 DK DK91303970.7T patent/DK0462696T3/da active
- 1991-05-02 NO NO911723A patent/NO179411C/no unknown
- 1991-05-02 PT PT97547A patent/PT97547B/pt not_active IP Right Cessation
- 1991-05-02 JP JP13047291A patent/JP3296499B2/ja not_active Expired - Fee Related
- 1991-05-02 KR KR1019910007086A patent/KR100195345B1/ko not_active Expired - Fee Related
- 1991-05-02 AT AT91303970T patent/ATE126231T1/de not_active IP Right Cessation
- 1991-05-02 DE DE69111915T patent/DE69111915T2/de not_active Expired - Fee Related
- 1991-05-02 MY MYPI91000748A patent/MY106552A/en unknown
- 1991-05-03 TN TNTNSN91030A patent/TNSN91030A1/fr unknown
- 1991-05-03 CN CN91103594A patent/CN1034077C/zh not_active Expired - Fee Related
- 1991-07-20 TW TW080105637A patent/TW218878B/zh active
1995
- 1995-07-29 CN CN95109346A patent/CN1039416C/zh not_active Expired - Fee Related
- 1995-09-06 GR GR950402432T patent/GR3017305T3/el unknown
1996
- 1996-03-21 HK HK51496A patent/HK51496A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0462696B1 (en)	1995-08-09
FI912124A0 (fi)	1991-05-02
IL120446A (en)	2000-08-31
EP0462696A1 (en)	1991-12-27
IL120446A0 (en)	1997-07-13
TNSN91030A1 (fr)	1992-10-25
HU218909B (hu)	2000-12-28
NZ237988A (en)	1992-09-25
KR910020019A (ko)	1991-12-19
PT97547B (pt)	1998-08-31
NO179411B (no)	1996-06-24
NO179411C (no)	1996-10-02
ZA913319B (en)	1993-01-27
DK0462696T3 (da)	1995-09-18
AU651580B2 (en)	1994-07-28
JP3296499B2 (ja)	2002-07-02
TW218878B (ja)	1994-01-11
AU7635491A (en)	1991-11-07
HK51496A (en)	1996-03-29
FI912124A7 (fi)	1991-11-04
HU911476D0 (en)	1991-11-28
ATE126231T1 (de)	1995-08-15
CA2041594C (en)	2002-07-23
NO911723D0 (no)	1991-05-02
FI95912B (fi)	1995-12-29
DE69111915T2 (de)	1996-01-04
IE911488A1 (en)	1991-11-06
IE68524B1 (en)	1996-06-26
PT97547A (pt)	1992-01-31
IL120447A (en)	1999-12-22
DE69111915D1 (de)	1995-09-14
ES2079570T3 (es)	1996-01-16
GR3017305T3 (en)	1995-12-31
IL127047A0 (en)	1999-09-22
IL97999A0 (en)	1992-06-21
CN1039416C (zh)	1998-08-05
JPH04225986A (ja)	1992-08-14
FI95912C (fi)	1996-04-10
CA2041594A1 (en)	1991-11-04
KR100195345B1 (ko)	1999-06-15
NO911723L (no)	1991-11-04
HUT60745A (en)	1992-10-28
IL97999A (en)	1997-06-10
CN1118783A (zh)	1996-03-20
MY106552A (en)	1995-06-30
IL120447A0 (en)	1997-07-13
US5075440A (en)	1991-12-24
IL127047A (en)	2000-10-31
CN1034077C (zh)	1997-02-19
CN1056880A (zh)	1991-12-11

Publication	Publication Date	Title
TW218878B (ja)	1994-01-11
IL94303A0 (en)	1991-03-10	Preparation of diazabicyclic intermediates
PL295306A1 (en)	1993-03-08	Method of obtaining novel derivatives of imidazo /2,1-b/benzothiazolo-3-acetamide
PT84648A (en)	1987-05-01	Substituted thiacycloalkeno ]3,2-b" pyridines methods of preparation compositions and method of use
NZ220996A (en)	1990-02-26	1,2,3 thiadiazole-4-thiolates
PL263015A1 (en)	1988-09-01	The method of manufacture of derivatives of 6-h-indol/2,3-b/-quinoline