AP1772A - Compounds that modulate PPAR activity and methods for their preparation. - Google Patents

Compounds that modulate PPAR activity and methods for their preparation.

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Publication number
AP1772A
AP1772A APAP/P/2004/003135A AP2004003135A AP1772A AP 1772 A AP1772 A AP 1772A AP 2004003135 A AP2004003135 A AP 2004003135A AP 1772 A AP1772 A AP 1772A
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AP
ARIPO
Prior art keywords
compounds
methods
discloses
preparation
ppar activity
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APAP/P/2004/003135A
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AP2004003135A0 (en
Inventor
Gary Frederick Filzen
Bharat Kalidas Trivedi
Andrew George Geyer
Paul Charles Unangst
Larry Don Bratton
Bruce Jeffrey Auerbach
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Warner Lambert Co
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Publication of AP2004003135A0 publication Critical patent/AP2004003135A0/en
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Publication of AP1772A publication Critical patent/AP1772A/en

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Abstract

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing hyperlipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of suppressing appetite.and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.
APAP/P/2004/003135A 2002-04-05 2003-03-24 Compounds that modulate PPAR activity and methods for their preparation. AP1772A (en)

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