AP2007004174A0 - Substituted aryl 1,4-pyrazine derivatives - Google Patents

Substituted aryl 1,4-pyrazine derivatives

Info

Publication number
AP2007004174A0
AP2007004174A0 AP2007004174A AP2007004174A AP2007004174A0 AP 2007004174 A0 AP2007004174 A0 AP 2007004174A0 AP 2007004174 A AP2007004174 A AP 2007004174A AP 2007004174 A AP2007004174 A AP 2007004174A AP 2007004174 A0 AP2007004174 A0 AP 2007004174A0
Authority
AP
ARIPO
Prior art keywords
substituted aryl
pyrazine derivatives
pyrazine
derivatives
aryl
Prior art date
Application number
AP2007004174A
Other languages
English (en)
Inventor
Robert Louis Hoffman
Patrick Robert Verhoest
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AP2007004174A0 publication Critical patent/AP2007004174A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
AP2007004174A 2005-03-17 2006-03-06 Substituted aryl 1,4-pyrazine derivatives AP2007004174A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66291705P 2005-03-17 2005-03-17
PCT/IB2006/000564 WO2006114666A1 (en) 2005-03-17 2006-03-06 SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES

Publications (1)

Publication Number Publication Date
AP2007004174A0 true AP2007004174A0 (en) 2007-10-31

Family

ID=36617394

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2007004174A AP2007004174A0 (en) 2005-03-17 2006-03-06 Substituted aryl 1,4-pyrazine derivatives

Country Status (26)

Country Link
US (1) US20060211710A1 (es)
EP (1) EP1871763A1 (es)
JP (1) JP2008533124A (es)
KR (1) KR20070113294A (es)
CN (1) CN101160304A (es)
AP (1) AP2007004174A0 (es)
AR (1) AR056279A1 (es)
AU (1) AU2006238976A1 (es)
BR (1) BRPI0606284A2 (es)
CA (1) CA2601600C (es)
CR (1) CR9436A (es)
DO (1) DOP2006000056A (es)
EA (1) EA012874B1 (es)
GT (1) GT200600116A (es)
IL (1) IL185997A0 (es)
MA (1) MA29336B1 (es)
MX (1) MX2007011423A (es)
NL (1) NL1031384C2 (es)
NO (1) NO20075209L (es)
PE (1) PE20061108A1 (es)
TN (1) TNSN07355A1 (es)
TW (1) TWI315670B (es)
UA (1) UA86873C2 (es)
UY (1) UY29418A1 (es)
WO (1) WO2006114666A1 (es)
ZA (1) ZA200707933B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
RU2543484C2 (ru) * 2009-10-30 2015-03-10 Янссен Фармацевтика Нв Пиразины для использования в качестве модуляторов дельта-опиоидных рецепторов
WO2011092290A1 (en) 2010-02-01 2011-08-04 Novartis Ag Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
EP2531490B1 (en) 2010-02-02 2014-10-15 Novartis AG Cyclohexyl amide derivatives as crf receptor antagonists
JP2022062287A (ja) * 2019-02-27 2022-04-20 住友化学株式会社 ピリジルピラジン化合物の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883105A (en) * 1996-04-03 1999-03-16 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5880140A (en) * 1996-04-03 1999-03-09 Merck & Co., Inc. Biheteroaryl inhibitors of farnesyl-protein transferase
US5872136A (en) * 1996-04-03 1999-02-16 Merck & Co., Inc. Arylheteroaryl inhibitors of farnesyl-protein transferase
PA8467401A1 (es) * 1998-02-17 2000-09-29 Pfizer Prod Inc Procedimiento para tratar la insuficiencia cardiaca
WO2001025220A1 (en) * 1999-10-07 2001-04-12 Amgen Inc. Triazine kinase inhibitors
CO5271670A1 (es) * 1999-10-29 2003-04-30 Pfizer Prod Inc Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas
CN1231473C (zh) * 2000-02-16 2005-12-14 神经能质公司 取代的芳基吡嗪
AU2002343557A1 (en) * 2001-11-21 2003-06-10 Pharmacia And Upjohn Company Substituted aryl 1,4-pyrazine derivatives
US6992087B2 (en) * 2001-11-21 2006-01-31 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
CA2480497A1 (en) * 2002-04-26 2003-11-06 Pharmacia & Upjohn Company Substituted pyrazine derivatives
US20040116444A1 (en) * 2002-09-12 2004-06-17 Corbett Jeffrey W. Substituted 1,4-pyrazine derivatives

Also Published As

Publication number Publication date
DOP2006000056A (es) 2006-08-30
PE20061108A1 (es) 2006-10-13
IL185997A0 (en) 2008-01-20
US20060211710A1 (en) 2006-09-21
KR20070113294A (ko) 2007-11-28
EA200701758A1 (ru) 2008-02-28
JP2008533124A (ja) 2008-08-21
TWI315670B (en) 2009-10-11
TNSN07355A1 (fr) 2008-12-31
CN101160304A (zh) 2008-04-09
AR056279A1 (es) 2007-10-03
CA2601600A1 (en) 2006-11-02
NL1031384A1 (nl) 2006-09-20
WO2006114666A8 (en) 2008-04-03
CR9436A (es) 2007-11-23
MX2007011423A (es) 2007-10-12
EP1871763A1 (en) 2008-01-02
WO2006114666A1 (en) 2006-11-02
GT200600116A (es) 2006-11-09
MA29336B1 (fr) 2008-03-03
NO20075209L (no) 2007-10-11
TW200700067A (en) 2007-01-01
NL1031384C2 (nl) 2007-01-23
BRPI0606284A2 (pt) 2009-06-09
UA86873C2 (en) 2009-05-25
UY29418A1 (es) 2006-10-31
CA2601600C (en) 2010-09-14
ZA200707933B (en) 2009-08-26
AU2006238976A1 (en) 2006-11-02
EA012874B1 (ru) 2009-12-30

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