AP2007004198A0 - Bicyclic [3.1.0] heteroaryl amides as type I glycine transport inhibitors - Google Patents

Bicyclic [3.1.0] heteroaryl amides as type I glycine transport inhibitors

Info

Publication number: AP2007004198A0
Authority: AP; ARIPO
Prior art keywords: bicyclic; type; transport inhibitors; glycine transport; heteroaryl amides
Prior art date: 2005-04-08

Application number

AP2007004198A

Other languages

English (en)

Inventor

Stanton Furst Mchardy

John Adams Lowe Iii

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-08

Filing date

2006-03-27

Publication date

2007-10-31

2006-03-27 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2007-10-31 Publication of AP2007004198A0 publication Critical patent/AP2007004198A0/xx

Links

DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title 2
239000004471 Glycine Substances 0.000 title 1
125000002619 bicyclic group Chemical group 0.000 title 1
-1 heteroaryl amides Chemical class 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AP2007004198A 2005-04-08 2006-03-27 Bicyclic [3.1.0] heteroaryl amides as type I glycine transport inhibitors AP2007004198A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US66947205P	2005-04-08	2005-04-08
PCT/IB2006/000947 WO2006106425A1 (fr)	2005-04-08	2006-03-27	Heteroarylamides bicycliques [3.1.0 ] comme inhibiteurs de transport de la glycine

Publications (1)

Publication Number	Publication Date
AP2007004198A0 true AP2007004198A0 (en)	2007-10-31

Family

ID=36649611

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2007004198A AP2007004198A0 (en)	2005-04-08	2006-03-27	Bicyclic [3.1.0] heteroaryl amides as type I glycine transport inhibitors

Country Status (31)

Country	Link
US (2)	US20060229455A1 (fr)
EP (1)	EP1869019B1 (fr)
JP (1)	JP4193949B2 (fr)
KR (1)	KR100969402B1 (fr)
CN (1)	CN101189228A (fr)
AP (1)	AP2007004198A0 (fr)
AR (1)	AR056307A1 (fr)
AU (1)	AU2006231917B2 (fr)
BR (1)	BRPI0608148A2 (fr)
CA (1)	CA2603939C (fr)
CR (1)	CR9493A (fr)
DK (1)	DK1869019T3 (fr)
DO (1)	DOP2006000078A (fr)
EA (1)	EA014311B1 (fr)
ES (1)	ES2520015T3 (fr)
GE (1)	GEP20105053B (fr)
GT (1)	GT200600136A (fr)
HN (1)	HN2006013804A (fr)
IL (1)	IL186409A (fr)
MA (1)	MA29672B1 (fr)
MX (1)	MX2007012463A (fr)
NL (1)	NL1031539C2 (fr)
NO (1)	NO339422B1 (fr)
NZ (1)	NZ563238A (fr)
PE (1)	PE20061400A1 (fr)
TN (1)	TNSN07380A1 (fr)
TW (1)	TW200719890A (fr)
UA (1)	UA88518C2 (fr)
UY (1)	UY29456A1 (fr)
WO (1)	WO2006106425A1 (fr)
ZA (1)	ZA200708481B (fr)

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WO2008065500A2 (fr) *	2006-11-30	2008-06-05	Pfizer Products Inc.	Hétéroaryl amides comme inhibiteurs du transport de la glycine de type i
WO2009131958A2 (fr) *	2008-04-21	2009-10-29	Institute For Oneworld Health	Composés, compositions et procédés à base de dérivés de triazine
US20090270398A1 (en) *	2008-04-21	2009-10-29	Institute For Oneworld Health	Compounds, Compositions and Methods Comprising Pyridazine Derivatives
WO2009131957A2 (fr)	2008-04-21	2009-10-29	Institute For Oneworld Health	Composés, compositions et traitements comprenant des dérivés d'oxydiazoles
WO2010033626A1 (fr) *	2008-09-19	2010-03-25	Institute For Oneworld Health	Composés, compositions et procédés comprenant des dérivés d'imidazole et de triazole
FR2932479A1 (fr) *	2008-06-13	2009-12-18	Servier Lab	Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CA2735764C (fr) *	2008-09-02	2016-06-14	Ortho-Mcneil-Janssen Pharmaceuticals, Inc.	Derives de 3-azabicyclo[3.1.0]hexyle comme modulateurs des recepteurs metabotropiques du glutamate
US8642772B2 (en)	2008-10-14	2014-02-04	Sk Biopharmaceuticals Co., Ltd.	Piperidine compounds, pharmaceutical composition comprising the same and its use
US8623898B2 (en)	2009-03-19	2014-01-07	Taisho Pharmaceutical Co., Ltd.	Glycine transporter inhibiting substances
US8343976B2 (en)	2009-04-20	2013-01-01	Institute For Oneworld Health	Compounds, compositions and methods comprising pyrazole derivatives
US20100267706A1 (en) *	2009-04-20	2010-10-21	Institute For Oneworld Health	Compounds, Compositions and Methods Comprising Pyridazine Derivatives
US8232315B2 (en)	2009-06-26	2012-07-31	Sk Biopharmaceuticals Co., Ltd.	Methods for treating drug addiction and improving addiction-related behavior
AR077472A1 (es) *	2009-07-15	2011-08-31	Taisho Pharmaceutical Co Ltd	Inhibidores de transportador de glicina
WO2011055944A2 (fr)	2009-11-06	2011-05-12	Sk Holdings Co., Ltd.	Procédés pour traiter un syndrome de fibromyalgie
KR101783632B1 (ko)	2009-11-06	2017-10-10	에스케이바이오팜 주식회사	주의력 결핍/과잉행동 장애(ａｄｈｄ)의 치료 방법
US9610274B2 (en)	2010-06-30	2017-04-04	Sk Biopharmaceuticals Co., Ltd.	Methods for treating bipolar disorder
US8623913B2 (en)	2010-06-30	2014-01-07	Sk Biopharmaceuticals Co., Ltd.	Methods for treating restless legs syndrome
US20120035156A1 (en) *	2010-08-09	2012-02-09	Daniela Alberati	Combination of glyt1 compound with antipsychotics
JP2013249257A (ja) *	2010-09-16	2013-12-12	Taisho Pharmaceutical Co Ltd	グリシントランスポーター阻害物質
WO2012036278A1 (fr)	2010-09-17	2012-03-22	大正製薬株式会社	Inhibiteur de transporteur de glycine
JP2013249258A (ja) *	2010-09-17	2013-12-12	Taisho Pharmaceutical Co Ltd	グリシントランスポーター阻害物質
BR112013007566A2 (pt)	2010-09-28	2016-08-02	Panacea Biotec Ltd	novos compostos bicíclicos
DK2909181T3 (da) *	2012-10-16	2017-11-20	Tolero Pharmaceuticals Inc	PKM2-modulatorer og fremgangsmåder til anvendelse deraf
WO2014078568A1 (fr)	2012-11-14	2014-05-22	The Johns Hopkins University	Méthodes et compositions pour le traitement de la schizophrénie
EP3134406A1 (fr)	2014-04-24	2017-03-01	Dart Neuroscience (Cayman) Ltd	Composés de 2,4,5,6-tétrahydropyrrolo[3,4-c]pyrazole et 4,5,6,7-tétrahydro-2 h-pyrazolo [4,3-c]pyridine utilisés comme inhibiteurs de glyt1
US10040759B2 (en)	2014-11-05	2018-08-07	Dart Neuroscience (Cayman) Ltd.	Substituted azetidinyl compounds as GlyT1 inhibitors
CN118593482A (zh)	2017-12-05	2024-09-06	赛诺维信制药公司	非外消旋混合物及其用途
WO2019113084A1 (fr)	2017-12-05	2019-06-13	Sunovion Pharmaceuticals Inc.	Formes cristallines et leurs procédés de production
EP3941463A1 (fr)	2019-03-22	2022-01-26	Sumitomo Dainippon Pharma Oncology, Inc.	Compositions comprenant des modulateurs de pkm2 et méthodes de traitement les utilisant
US11274082B2 (en)	2019-05-31	2022-03-15	Ikena Oncology, Inc.	Tead inhibitors and uses thereof
WO2020243423A1 (fr)	2019-05-31	2020-12-03	Ikena Oncology, Inc.	Inhibiteurs de tead et leurs utilisations
MX2021014774A (es)	2019-06-04	2022-02-03	Sunovion Pharmaceuticals Inc	Formulaciones de liberacion modificada y usos de las mismas.
EP4087570A4 (fr)	2020-01-09	2024-04-03	Disc Medicine, Inc.	Méthodes de traitement de protoporphyrie érythropoïétique, de protoporphyrie liée à x ou de porphyrie érythropoïétique congénitale avec des inhibiteurs de transport de glycine
EP4196118A1 (fr)	2020-08-13	2023-06-21	Boehringer Ingelheim International GmbH	Traitement de la déficience cognitive associée à la schizophrénie
CN117567449A (zh)	2020-10-13	2024-02-20	勃林格殷格翰国际有限公司	再加工方法

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CN1291984A (zh)	1998-03-06	2001-04-18	詹森药业有限公司	甘氨酸传输抑制剂
JP2002212179A (ja)	2001-01-15	2002-07-31	Wakunaga Pharmaceut Co Ltd	新規アニリド誘導体又はその塩及びこれを含有する医薬
CA2468761A1 (fr)	2001-10-31	2003-05-08	Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie	Nouveaux composes anticancereux
FR2838739B1 (fr) *	2002-04-19	2004-05-28	Sanofi Synthelabo	Derives de n-[phenyl(piperidin-2-yl)methyl)benzamide, leur preparation et leur application en therapeutique
US7160888B2 (en) *	2003-08-22	2007-01-09	Warner Lambert Company Llc	[1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
ES2634841T3 (es) *	2003-10-14	2017-09-29	Pfizer Products Inc.	Derivados bicíclicos [3.1.0] como inhibidores del transportador de glicina
AU2005247943A1 (en)	2004-05-23	2005-12-08	Gerard M. Housey	Theramutein modulators

2006
- 2006-03-27 KR KR1020077025888A patent/KR100969402B1/ko not_active Expired - Fee Related
- 2006-03-27 EA EA200701902A patent/EA014311B1/ru not_active IP Right Cessation
- 2006-03-27 JP JP2008504868A patent/JP4193949B2/ja not_active Expired - Fee Related
- 2006-03-27 NZ NZ563238A patent/NZ563238A/en not_active IP Right Cessation
- 2006-03-27 ES ES06727516.4T patent/ES2520015T3/es not_active Expired - Lifetime
- 2006-03-27 WO PCT/IB2006/000947 patent/WO2006106425A1/fr not_active Ceased
- 2006-03-27 GE GEAP200610309A patent/GEP20105053B/en unknown
- 2006-03-27 UA UAA200711021A patent/UA88518C2/ru unknown
- 2006-03-27 CA CA2603939A patent/CA2603939C/fr not_active Expired - Fee Related
- 2006-03-27 DK DK06727516.4T patent/DK1869019T3/da active
- 2006-03-27 EP EP06727516.4A patent/EP1869019B1/fr not_active Expired - Lifetime
- 2006-03-27 AP AP2007004198A patent/AP2007004198A0/xx unknown
- 2006-03-27 CN CNA2006800198904A patent/CN101189228A/zh active Pending
- 2006-03-27 BR BRPI0608148-7A patent/BRPI0608148A2/pt not_active IP Right Cessation
- 2006-03-27 MX MX2007012463A patent/MX2007012463A/es active IP Right Grant
- 2006-03-27 AU AU2006231917A patent/AU2006231917B2/en not_active Ceased
- 2006-03-31 DO DO2006000078A patent/DOP2006000078A/es unknown
- 2006-04-05 UY UY29456A patent/UY29456A1/es unknown
- 2006-04-06 AR ARP060101362A patent/AR056307A1/es unknown
- 2006-04-06 GT GT200600136A patent/GT200600136A/es unknown
- 2006-04-06 US US11/399,071 patent/US20060229455A1/en not_active Abandoned
- 2006-04-06 PE PE2006000374A patent/PE20061400A1/es not_active Application Discontinuation
- 2006-04-06 HN HN2006013804A patent/HN2006013804A/es unknown
- 2006-04-07 TW TW095112431A patent/TW200719890A/zh unknown
- 2006-04-07 NL NL1031539A patent/NL1031539C2/nl not_active IP Right Cessation
2007
- 2007-10-03 NO NO20074993A patent/NO339422B1/no not_active IP Right Cessation
- 2007-10-04 ZA ZA200708481A patent/ZA200708481B/xx unknown
- 2007-10-07 IL IL186409A patent/IL186409A/en active IP Right Grant
- 2007-10-08 MA MA30281A patent/MA29672B1/fr unknown
- 2007-10-08 TN TNP2007000380A patent/TNSN07380A1/fr unknown
- 2007-11-01 CR CR9493A patent/CR9493A/es not_active Application Discontinuation
2010
- 2010-08-30 US US12/870,928 patent/US8124639B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NZ563238A (en)	2011-01-28
NL1031539C2 (nl)	2007-04-10
BRPI0608148A2 (pt)	2009-11-10
EA200701902A1 (ru)	2008-04-28
HN2006013804A (es)	2009-10-30
CN101189228A (zh)	2008-05-28
AU2006231917A1 (en)	2006-10-12
ZA200708481B (en)	2010-05-26
US8124639B2 (en)	2012-02-28
KR20070120582A (ko)	2007-12-24
NO20074993L (no)	2007-11-02
TNSN07380A1 (fr)	2009-03-17
MX2007012463A (es)	2007-11-07
PE20061400A1 (es)	2007-01-15
US20100324020A1 (en)	2010-12-23
TW200719890A (en)	2007-06-01
US20060229455A1 (en)	2006-10-12
DK1869019T3 (da)	2014-10-06
DOP2006000078A (es)	2006-10-15
WO2006106425A1 (fr)	2006-10-12
GT200600136A (es)	2006-11-07
IL186409A0 (en)	2008-01-20
ES2520015T3 (es)	2014-11-11
JP4193949B2 (ja)	2008-12-10
GEP20105053B (en)	2010-07-26
KR100969402B1 (ko)	2010-07-14
AU2006231917B2 (en)	2011-07-28
UA88518C2 (ru)	2009-10-26
MA29672B1 (fr)	2008-08-01
JP2008534671A (ja)	2008-08-28
NO339422B1 (no)	2016-12-12
IL186409A (en)	2012-07-31
AR056307A1 (es)	2007-10-03
CA2603939A1 (fr)	2006-10-12
EP1869019B1 (fr)	2014-08-27
EP1869019A1 (fr)	2007-12-26
UY29456A1 (es)	2006-11-30
CA2603939C (fr)	2013-08-27
EA014311B1 (ru)	2010-10-29
NL1031539A1 (nl)	2006-10-10
CR9493A (es)	2007-12-04

Publication	Publication Date	Title
IL186409A0 (en)	2008-01-20	Bicyclic [3.1.0]heteroaryl amides as type 1 glycine transport inhibitors
TWI372152B (en)	2012-09-11	Novel peptide compounds
IL192053A0 (en)	2008-12-29	2-adamantylurea derivatives as selective 11??-hsd1 inhibitors
IL174299A0 (en)	2006-08-01	Bicyclic [3.1.0] derivatives as glycine transporter inhibitors
ZA200707650B (en)	2008-11-26	Azolylacylguanidines as ß-secretase inhibitors
IL183975A0 (en)	2007-10-31	Glycine transport inhibitors
IL188643A0 (en)	2008-04-13	N-(heteroaryl)-1-heteroarylalkyl-1h-indole-2-
ZA200808747B (en)	2009-12-30	Fertilizer
GB0508863D0 (en)	2005-06-08	Peptide
IL172694A0 (en)	2006-04-10	6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors
IL185790A0 (en)	2008-01-06	Amino acid derivatives
IL184271A0 (en)	2007-10-31	Peptidic compounds
GB0514482D0 (en)	2005-08-17	Protein
ZA200704726B (en)	2009-02-25	Glycine transport inhibitors
GB2420331B (en)	2008-03-19	Intermodal trailer
GB0522113D0 (en)	2005-12-07	vWFA-domain containing proteins
PL372062A1 (pl)	2006-07-10	Blok transportowy
HK1124042A (en)	2009-07-03	Pyrimido- [4, 5-]-oxazines for use as dgat inhibitors
HK1105596A (en)	2008-02-22	Lactam compounds useful as protein kinase inhibitors
GB0516303D0 (en)	2005-09-14	Peptide
ZA200709294B (en)	2009-01-28	Peptide
PL119827U1 (pl)	2011-10-24	System zraszania kombajnu węglowego
HK1111404A (en)	2008-08-08	Glycine transport inhibitors
PH32005001210S1 (en)	2007-07-25	100 plus bottle
GB0408850D0 (en)	2004-05-26	Improved transporter