AP2015008714A0 - Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment - Google Patents

Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Info

Publication number
AP2015008714A0
AP2015008714A0 AP2015008714A AP2015008714A AP2015008714A0 AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0 AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0
Authority
AP
ARIPO
Prior art keywords
albumin
pharmaceutical composition
arginine deiminase
cancer targeting
targeting treatment
Prior art date
Application number
AP2015008714A
Other languages
English (en)
Inventor
Yun Chung Leung
Sui Yi Kwok
Norman Fung Man Wai
Original Assignee
Vision Global Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vision Global Holdings Ltd filed Critical Vision Global Holdings Ltd
Publication of AP2015008714A0 publication Critical patent/AP2015008714A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03006—Arginine deiminase (3.5.3.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AP2015008714A 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment AP2015008714A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773214P 2013-03-06 2013-03-06
US14/197,236 US9255262B2 (en) 2013-03-06 2014-03-05 Albumin-binding arginine deminase and the use thereof
PCT/US2014/020943 WO2014138319A2 (en) 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Publications (1)

Publication Number Publication Date
AP2015008714A0 true AP2015008714A0 (en) 2015-09-30

Family

ID=51488086

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008714A AP2015008714A0 (en) 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Country Status (21)

Country Link
US (3) US9255262B2 (de)
EP (1) EP2964761B1 (de)
JP (1) JP6243452B2 (de)
KR (1) KR102139844B1 (de)
CN (1) CN105142663B (de)
AP (1) AP2015008714A0 (de)
AU (1) AU2014225712C1 (de)
BR (1) BR112015021182A2 (de)
CA (1) CA2903152C (de)
CL (1) CL2015002479A1 (de)
EA (1) EA036064B1 (de)
ES (1) ES2909664T3 (de)
IL (1) IL240976A (de)
MA (1) MA38376B1 (de)
MX (1) MX379135B (de)
MY (1) MY175144A (de)
PH (1) PH12015501995A1 (de)
SA (1) SA515360970B1 (de)
SG (1) SG11201506679QA (de)
TW (1) TWI634212B (de)
WO (1) WO2014138319A2 (de)

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US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
GEP20237497B (en) 2013-10-18 2023-04-10 Deutsches Krebsforsch Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
CN105985447B (zh) * 2015-03-02 2019-10-22 四川大学华西医院 一种白蛋白结合型肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
CN104789489B (zh) * 2015-03-09 2018-01-23 武汉远大弘元股份有限公司 一株高产精氨酸脱亚胺酶的蜡样芽孢杆菌及其应用
EP4582098A3 (de) * 2015-11-09 2025-12-24 CureVac SE Optimierte nukleinsäuremoleküle
TWI660042B (zh) * 2017-01-18 2019-05-21 展旺生命科技股份有限公司 用以製備目標蛋白的表現構建體與方法
EP3449935A1 (de) * 2017-08-31 2019-03-06 Erytech Pharma In erythrozyten eingekapselte arginin-deiminase und deren verwendung zur behandlung von krebs und arginase-1-mangel
WO2020009740A2 (en) 2018-04-25 2020-01-09 Washington University Compositions and methods of use thereof for treatment of metabolic diseases and related disorders
CN112513099A (zh) * 2018-05-31 2021-03-16 香港理工大学 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用
US20220363778A1 (en) * 2019-08-28 2022-11-17 The Research Foundation For The State University Of New York Targeted delivery of tumor matrix modifying enzymes
CN111394295B (zh) * 2019-11-06 2023-03-10 上海健康医学院 一种制备固定化精氨酸脱亚胺酶及生产[14/15n]-l-瓜氨酸的方法
CN111518851B (zh) * 2019-11-06 2023-05-23 上海健康医学院 一种固定化酶连续制备[14/15n]-l-瓜氨酸的方法
CN115038460A (zh) * 2019-12-02 2022-09-09 香港理工大学 诱导间歇性禁食和调节自噬的方法
CA3187578A1 (en) * 2020-06-29 2022-01-06 Vision Global Holdings Limited Method of treating aml subtypes using arginine-depleting agents
KR102501387B1 (ko) 2020-09-25 2023-02-24 주식회사 프로앱텍 요산산화효소-알부민 접합체, 그 제조방법 및 용도
WO2022065936A1 (ko) * 2020-09-25 2022-03-31 주식회사 프로앱텍 기능성 폴리펩티드 변이체의 컨쥬게이트 및 그 용도
CN113584054B (zh) * 2021-06-28 2023-04-18 河北远大九孚生物科技有限公司 编码精氨酸脱亚胺酶的dna分子及其用途

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JP2900279B2 (ja) * 1989-08-02 1999-06-02 株式会社ジャパンエナジー 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤
US5196195A (en) * 1990-03-27 1993-03-23 Cornell Research Foundation, Inc. Use of arginase to control nitric oxide formation
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5804183A (en) * 1997-01-31 1998-09-08 Enzon, Inc. Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
US6183738B1 (en) 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
US6180387B1 (en) * 1997-08-11 2001-01-30 Smithkline Beecham Corporation Arginine deiminase
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WO2003099843A2 (en) 2002-05-20 2003-12-04 Dow Corning Corporation Peptide derivatives, and their use for the synthesis of silicon-based composite materials
HUE027902T2 (en) * 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
CN1292002C (zh) * 2004-10-21 2006-12-27 北京双鹭药业股份有限公司 一种精氨酸脱酰酶融合蛋白、其制造方法及应用
ES2379283T3 (es) 2005-05-18 2012-04-24 Ablynx N.V. Proteínas de unión a albúmina sérica
CN101002945B (zh) * 2006-01-20 2012-09-05 清华大学 一种用于肿瘤治疗的新型复合物
KR100934656B1 (ko) 2006-02-06 2009-12-31 엘지전자 주식회사 다중 반송파 시스템에서의 무선 자원 할당 방법
EP2474318A1 (de) * 2006-06-07 2012-07-11 Human Genome Sciences, Inc. Albumin-Fusionsproteine
CA2659413C (en) 2006-08-01 2016-06-14 Pieris Ag Muteins of tear lipocalin and methods for obtaining the same
EP2546261A3 (de) * 2007-07-31 2013-08-14 Affibody AB Neue Zusammensetzungen, Verfahren und Verwendung
EP2295560A1 (de) * 2009-09-14 2011-03-16 RWTH Aachen University Zielgerichtete Evolution von Arginindeiminase zur erhöhten Aktivität im physiologischen pH
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof

Also Published As

Publication number Publication date
EP2964761B1 (de) 2022-01-19
US20140255377A1 (en) 2014-09-11
BR112015021182A2 (pt) 2017-10-10
WO2014138319A2 (en) 2014-09-12
PH12015501995B1 (en) 2016-01-11
SA515360970B1 (ar) 2017-07-20
EA036064B1 (ru) 2020-09-22
SG11201506679QA (en) 2015-09-29
AU2014225712A1 (en) 2015-09-10
CN105142663B (zh) 2017-12-08
ES2909664T3 (es) 2022-05-09
CN105142663A (zh) 2015-12-09
WO2014138319A8 (en) 2015-01-22
HK1211979A1 (en) 2016-06-03
MX2015011578A (es) 2016-04-25
MA38376B1 (fr) 2019-03-29
CL2015002479A1 (es) 2016-05-13
US20160115468A1 (en) 2016-04-28
MY175144A (en) 2020-06-10
PH12015501995A1 (en) 2016-01-11
IL240976A (en) 2016-09-29
CA2903152C (en) 2021-02-09
NZ711234A (en) 2021-01-29
JP6243452B2 (ja) 2017-12-06
TW201520336A (zh) 2015-06-01
EP2964761A4 (de) 2016-07-20
KR102139844B1 (ko) 2020-08-03
TWI634212B (zh) 2018-09-01
EA201500826A1 (ru) 2015-12-30
JP2016514111A (ja) 2016-05-19
WO2014138319A3 (en) 2014-12-24
AU2014225712B2 (en) 2017-04-06
IL240976A0 (en) 2015-11-30
MX379135B (es) 2025-03-10
MA38376A1 (fr) 2017-10-31
US9803185B2 (en) 2017-10-31
AU2014225712C1 (en) 2017-09-28
US9255262B2 (en) 2016-02-09
KR20150124999A (ko) 2015-11-06
EP2964761A2 (de) 2016-01-13
USRE47233E1 (en) 2019-02-12
CA2903152A1 (en) 2014-09-12

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