AP2015008714A0 - Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment - Google Patents

Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Info

Publication number
AP2015008714A0
AP2015008714A0 AP2015008714A AP2015008714A AP2015008714A0 AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0 AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0
Authority
AP
ARIPO
Prior art keywords
albumin
pharmaceutical composition
arginine deiminase
cancer targeting
targeting treatment
Prior art date
Application number
AP2015008714A
Other languages
English (en)
Inventor
Yun Chung Leung
Sui Yi Kwok
Norman Fung Man Wai
Original Assignee
Vision Global Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vision Global Holdings Ltd filed Critical Vision Global Holdings Ltd
Publication of AP2015008714A0 publication Critical patent/AP2015008714A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03006—Arginine deiminase (3.5.3.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AP2015008714A 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment AP2015008714A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773214P 2013-03-06 2013-03-06
US14/197,236 US9255262B2 (en) 2013-03-06 2014-03-05 Albumin-binding arginine deminase and the use thereof
PCT/US2014/020943 WO2014138319A2 (fr) 2013-03-06 2014-03-06 Composition pharmaceutique comprenant l'arginine déiminase de liaison à l'albumine pour le traitement ciblé du cancer

Publications (1)

Publication Number Publication Date
AP2015008714A0 true AP2015008714A0 (en) 2015-09-30

Family

ID=51488086

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008714A AP2015008714A0 (en) 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Country Status (21)

Country Link
US (3) US9255262B2 (fr)
EP (1) EP2964761B1 (fr)
JP (1) JP6243452B2 (fr)
KR (1) KR102139844B1 (fr)
CN (1) CN105142663B (fr)
AP (1) AP2015008714A0 (fr)
AU (1) AU2014225712C1 (fr)
BR (1) BR112015021182A2 (fr)
CA (1) CA2903152C (fr)
CL (1) CL2015002479A1 (fr)
EA (1) EA036064B1 (fr)
ES (1) ES2909664T3 (fr)
IL (1) IL240976A (fr)
MA (1) MA38376B1 (fr)
MX (1) MX379135B (fr)
MY (1) MY175144A (fr)
PH (1) PH12015501995A1 (fr)
SA (1) SA515360970B1 (fr)
SG (1) SG11201506679QA (fr)
TW (1) TWI634212B (fr)
WO (1) WO2014138319A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
EP3456700A1 (fr) 2013-10-18 2019-03-20 Deutsches Krebsforschungszentrum Inhibiteurs marqués de l'antigène membranaire spécifique de la prostate (psma), leur utilisation comme agents d'imagerie et agents pharmaceutiques pour le traitement du cancer de la prostate
CN105985447B (zh) * 2015-03-02 2019-10-22 四川大学华西医院 一种白蛋白结合型肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
CN104789489B (zh) * 2015-03-09 2018-01-23 武汉远大弘元股份有限公司 一株高产精氨酸脱亚胺酶的蜡样芽孢杆菌及其应用
EP3374504B1 (fr) * 2015-11-09 2025-03-19 CureVac SE Molécules d'acide nucléique optimisées
WO2018136572A1 (fr) * 2017-01-18 2018-07-26 Savior Lifetec Corporation Construction d'expression et procédé de production de protéines d'intérêt
EP3449935A1 (fr) * 2017-08-31 2019-03-06 Erytech Pharma Arginine deiminase encapsulée à l'intérieur des érythrocytes et leur utilisation dans le traitement du cancer et de la déficience en arginase-1
US12508306B2 (en) 2018-04-25 2025-12-30 Washington University Compositions and methods of use thereof for treatment of metabolic diseases and related disorders
AU2019275733B2 (en) 2018-05-31 2025-07-31 The Chinese University Of Hong Kong Composition and application of arginine-depleting agents for cancer, obesity, metabolic disorders, and related complications and comorbidities
US20220363778A1 (en) * 2019-08-28 2022-11-17 The Research Foundation For The State University Of New York Targeted delivery of tumor matrix modifying enzymes
CN111518851B (zh) * 2019-11-06 2023-05-23 上海健康医学院 一种固定化酶连续制备[14/15n]-l-瓜氨酸的方法
CN111394295B (zh) * 2019-11-06 2023-03-10 上海健康医学院 一种制备固定化精氨酸脱亚胺酶及生产[14/15n]-l-瓜氨酸的方法
US20210162028A1 (en) * 2019-12-02 2021-06-03 The Hong Kong Polytechnic University Methods for Inducing Intermittent Fasting and Modulating Autophagy
EP4153167A4 (fr) * 2020-06-29 2024-02-28 Vision Global Holdings Limited Méthode de traitement de sous-types de lma à l'aide d'agents de déplétion de l'arginine
CA3196814A1 (fr) 2020-09-25 2022-03-31 Proabtech Inc. Conjugue uricase-albumine, procede de preparation associe et son utilisation
EP4218825A4 (fr) * 2020-09-25 2025-03-19 Proabtech Inc. Conjugué de variant polypeptidique fonctionnel et son utilisation
CN113584054B (zh) * 2021-06-28 2023-04-18 河北远大九孚生物科技有限公司 编码精氨酸脱亚胺酶的dna分子及其用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2900279B2 (ja) * 1989-08-02 1999-06-02 株式会社ジャパンエナジー 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤
US5196195A (en) * 1990-03-27 1993-03-23 Cornell Research Foundation, Inc. Use of arginase to control nitric oxide formation
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5804183A (en) * 1997-01-31 1998-09-08 Enzon, Inc. Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
US6183738B1 (en) 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
US6180387B1 (en) * 1997-08-11 2001-01-30 Smithkline Beecham Corporation Arginine deiminase
GB9823071D0 (en) * 1998-10-21 1998-12-16 Affibody Technology Ab A method
US20040001827A1 (en) 2002-06-28 2004-01-01 Dennis Mark S. Serum albumin binding peptides for tumor targeting
EP2213743A1 (fr) * 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Protéines de fusion d'albumine
US20030157091A1 (en) 2002-02-14 2003-08-21 Dyax Corporation Multi-functional proteins
CA2485169C (fr) 2002-05-20 2013-03-26 Joseph C. Mcauliffe Derives de peptides et utilisation de ces derives pour la synthese de materiaux composites a base de silicium
HUE027902T2 (en) * 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
CN1292002C (zh) * 2004-10-21 2006-12-27 北京双鹭药业股份有限公司 一种精氨酸脱酰酶融合蛋白、其制造方法及应用
US8188223B2 (en) 2005-05-18 2012-05-29 Ablynx N.V. Serum albumin binding proteins
CN101002945B (zh) * 2006-01-20 2012-09-05 清华大学 一种用于肿瘤治疗的新型复合物
KR100934656B1 (ko) 2006-02-06 2009-12-31 엘지전자 주식회사 다중 반송파 시스템에서의 무선 자원 할당 방법
WO2007146038A2 (fr) * 2006-06-07 2007-12-21 Human Genome Sciences, Inc. Protéines de fusion d'albumine
EP2046820B1 (fr) 2006-08-01 2010-10-20 Pieris AG Mutéines de lipocaline lacrymale et procédés permettant d'obtenir lesdites mutéines
EP2190863B1 (fr) * 2007-07-31 2015-09-02 Affibody AB Nouvelles compositions, nouveaux procédés et nouvelles utilisations
EP2295560A1 (fr) * 2009-09-14 2011-03-16 RWTH Aachen University Évolution dirigée de l'arginine déiminase pour une activité accrue à un pH physiologique
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof

Also Published As

Publication number Publication date
JP6243452B2 (ja) 2017-12-06
US20140255377A1 (en) 2014-09-11
IL240976A (en) 2016-09-29
CL2015002479A1 (es) 2016-05-13
EP2964761A4 (fr) 2016-07-20
US20160115468A1 (en) 2016-04-28
BR112015021182A2 (pt) 2017-10-10
TW201520336A (zh) 2015-06-01
MX2015011578A (es) 2016-04-25
EA201500826A1 (ru) 2015-12-30
US9803185B2 (en) 2017-10-31
PH12015501995B1 (en) 2016-01-11
AU2014225712A1 (en) 2015-09-10
HK1211979A1 (en) 2016-06-03
NZ711234A (en) 2021-01-29
PH12015501995A1 (en) 2016-01-11
AU2014225712B2 (en) 2017-04-06
MA38376B1 (fr) 2019-03-29
EP2964761A2 (fr) 2016-01-13
KR20150124999A (ko) 2015-11-06
CA2903152A1 (fr) 2014-09-12
EA036064B1 (ru) 2020-09-22
CN105142663B (zh) 2017-12-08
WO2014138319A3 (fr) 2014-12-24
USRE47233E1 (en) 2019-02-12
US9255262B2 (en) 2016-02-09
KR102139844B1 (ko) 2020-08-03
CA2903152C (fr) 2021-02-09
WO2014138319A8 (fr) 2015-01-22
IL240976A0 (en) 2015-11-30
JP2016514111A (ja) 2016-05-19
ES2909664T3 (es) 2022-05-09
MY175144A (en) 2020-06-10
MA38376A1 (fr) 2017-10-31
MX379135B (es) 2025-03-10
WO2014138319A2 (fr) 2014-09-12
EP2964761B1 (fr) 2022-01-19
TWI634212B (zh) 2018-09-01
SG11201506679QA (en) 2015-09-29
SA515360970B1 (ar) 2017-07-20
AU2014225712C1 (en) 2017-09-28
CN105142663A (zh) 2015-12-09

Similar Documents

Publication Publication Date Title
IL240976A (en) An arginine-containing diminutin-related drug is an albumin used to treat cancer
IL289300A (en) Combination therapy for treating cancer
PL2818482T3 (pl) Kompozycja farmaceutyczna do leczenia nowotworu
PT2824114T (pt) Composição farmacêutica para o tratamento do cancro
ZA201407726B (en) Pharmaceutical compositions for combination therapy
IL234365B (en) Inhalable pharmaceutical compositions
PL3030262T3 (pl) Złożona kompozycja farmaceutyczna
HUE045314T2 (hu) Kombinációs terápia rák kezelésére
AP2015008875A0 (en) Low dose pharmaceutical composition
PL3089749T3 (pl) Preparaty skojarzone do leczenia raka
PL3062790T3 (pl) Połączenia farmaceutyczne do leczenia raka
LT2814473T (lt) Farmacinės kompozicijos, skirtos derinių terapijai
IL237146A0 (en) Pharmaceutical compound containing Rabamipide
EP3088001A4 (fr) Agent thérapeutique pour tumeur maligne
EP3020399A4 (fr) Nouvelle composition pharmaceutique pour prévenir ou traiter le cancer
EP2934500A4 (fr) Polythérapie pour le traitement du cancer
PL2855475T3 (pl) Alfa-karboliny do leczenia nowotworu
ZA201502571B (en) Pharmaceutical composition comprising benzyl alcohol for the treatment of migraines
EP2902027A4 (fr) Composition de médicament pour le traitement de tumeurs et son application
AU2013904239A0 (en) Pharmaceutical combinations for the treatment of cancer
IL238267B (en) Anthracycline derivatives for the treatment of tumor diseases
PT2814473T (pt) Composições farmacêuticas para terapia de combinação
IL239231A0 (en) Combined cancer treatment
AU2012905667A0 (en) Vaccines for treatment of cancer