AP2015008714A0 - Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment - Google Patents

Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Info

Publication number
AP2015008714A0
AP2015008714A0 AP2015008714A AP2015008714A AP2015008714A0 AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0 AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A AP2015008714 A AP 2015008714A AP 2015008714 A0 AP2015008714 A0 AP 2015008714A0
Authority
AP
ARIPO
Prior art keywords
albumin
pharmaceutical composition
arginine deiminase
cancer targeting
targeting treatment
Prior art date
Application number
AP2015008714A
Other languages
English (en)
Inventor
Yun Chung Leung
Sui Yi Kwok
Norman Fung Man Wai
Original Assignee
Vision Global Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vision Global Holdings Ltd filed Critical Vision Global Holdings Ltd
Publication of AP2015008714A0 publication Critical patent/AP2015008714A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03006—Arginine deiminase (3.5.3.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AP2015008714A 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment AP2015008714A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773214P 2013-03-06 2013-03-06
US14/197,236 US9255262B2 (en) 2013-03-06 2014-03-05 Albumin-binding arginine deminase and the use thereof
PCT/US2014/020943 WO2014138319A2 (en) 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Publications (1)

Publication Number Publication Date
AP2015008714A0 true AP2015008714A0 (en) 2015-09-30

Family

ID=51488086

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008714A AP2015008714A0 (en) 2013-03-06 2014-03-06 Pharmaceutical composition comprising albumin-binding arginine deiminase for cancer targeting treatment

Country Status (21)

Country Link
US (3) US9255262B2 (he)
EP (1) EP2964761B1 (he)
JP (1) JP6243452B2 (he)
KR (1) KR102139844B1 (he)
CN (1) CN105142663B (he)
AP (1) AP2015008714A0 (he)
AU (1) AU2014225712C1 (he)
BR (1) BR112015021182A2 (he)
CA (1) CA2903152C (he)
CL (1) CL2015002479A1 (he)
EA (1) EA036064B1 (he)
ES (1) ES2909664T3 (he)
IL (1) IL240976A (he)
MA (1) MA38376B1 (he)
MX (1) MX379135B (he)
MY (1) MY175144A (he)
PH (1) PH12015501995B1 (he)
SA (1) SA515360970B1 (he)
SG (1) SG11201506679QA (he)
TW (1) TWI634212B (he)
WO (1) WO2014138319A2 (he)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
EP3456700A1 (en) 2013-10-18 2019-03-20 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
CN105985447B (zh) * 2015-03-02 2019-10-22 四川大学华西医院 一种白蛋白结合型肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
CN104789489B (zh) * 2015-03-09 2018-01-23 武汉远大弘元股份有限公司 一株高产精氨酸脱亚胺酶的蜡样芽孢杆菌及其应用
WO2017081082A2 (en) * 2015-11-09 2017-05-18 Curevac Ag Optimized nucleic acid molecules
WO2018136572A1 (en) * 2017-01-18 2018-07-26 Savior Lifetec Corporation Expression construct and method for producing proteins of interest
EP3449935A1 (en) * 2017-08-31 2019-03-06 Erytech Pharma Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
US12508306B2 (en) 2018-04-25 2025-12-30 Washington University Compositions and methods of use thereof for treatment of metabolic diseases and related disorders
CN112513099A (zh) * 2018-05-31 2021-03-16 香港理工大学 用于癌症、肥胖症、代谢紊乱和相关并发症及合并症的精氨酸耗竭剂的组合物和应用
WO2021041954A2 (en) * 2019-08-28 2021-03-04 The Research Foundation For The State University Of New York Targeted delivery of tumor matrix modifying enzymes
CN111518851B (zh) * 2019-11-06 2023-05-23 上海健康医学院 一种固定化酶连续制备[14/15n]-l-瓜氨酸的方法
CN111394295B (zh) * 2019-11-06 2023-03-10 上海健康医学院 一种制备固定化精氨酸脱亚胺酶及生产[14/15n]-l-瓜氨酸的方法
WO2021110071A1 (en) * 2019-12-02 2021-06-10 The Hong Kong Polytechnic University Methods for inducing intermittent fasting and modulating autophagy
KR20230104110A (ko) * 2020-06-29 2023-07-07 비전 글로벌 홀딩스 리미티드. 아르기닌 고갈제를 사용하여 aml 아형을 치료하는 방법
US20230372503A1 (en) * 2020-09-25 2023-11-23 Proabtech Inc. Conjugate of functional polypeptide variant, and use thereof
KR102501387B1 (ko) 2020-09-25 2023-02-24 주식회사 프로앱텍 요산산화효소-알부민 접합체, 그 제조방법 및 용도
CN113584054B (zh) * 2021-06-28 2023-04-18 河北远大九孚生物科技有限公司 编码精氨酸脱亚胺酶的dna分子及其用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2900279B2 (ja) * 1989-08-02 1999-06-02 株式会社ジャパンエナジー 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤
US5196195A (en) * 1990-03-27 1993-03-23 Cornell Research Foundation, Inc. Use of arginase to control nitric oxide formation
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5804183A (en) * 1997-01-31 1998-09-08 Enzon, Inc. Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
US6183738B1 (en) 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
US6180387B1 (en) * 1997-08-11 2001-01-30 Smithkline Beecham Corporation Arginine deiminase
GB9823071D0 (en) * 1998-10-21 1998-12-16 Affibody Technology Ab A method
US20040001827A1 (en) 2002-06-28 2004-01-01 Dennis Mark S. Serum albumin binding peptides for tumor targeting
EP1274720A4 (en) * 2000-04-12 2004-08-18 Human Genome Sciences Inc FUSION PROTEINS CONTAINING ALBUMIN
US20030157091A1 (en) 2002-02-14 2003-08-21 Dyax Corporation Multi-functional proteins
ATE486043T1 (de) 2002-05-20 2010-11-15 Danisco Us Inc Peptidderivate und deren verwendung zur synthese von verbundwerkstoffen auf siliciumbasis
JP5010923B2 (ja) * 2004-02-09 2012-08-29 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド アルブミン融合蛋白質
CN1292002C (zh) 2004-10-21 2006-12-27 北京双鹭药业股份有限公司 一种精氨酸脱酰酶融合蛋白、其制造方法及应用
AU2006249144B2 (en) 2005-05-18 2011-11-17 Ablynx Nv Improved NanobodiesTM against Tumor Necrosis Factor-alpha
CN101002945B (zh) * 2006-01-20 2012-09-05 清华大学 一种用于肿瘤治疗的新型复合物
KR100934656B1 (ko) 2006-02-06 2009-12-31 엘지전자 주식회사 다중 반송파 시스템에서의 무선 자원 할당 방법
AU2007258609B2 (en) * 2006-06-07 2013-01-24 Human Genome Sciences, Inc. Albumin fusion proteins
SG173332A1 (en) 2006-08-01 2011-08-29 Pieris Ag Muteins of tear lipocalin and methods for obtaining the same
US8937153B2 (en) * 2007-07-31 2015-01-20 Affibody Ab Compositions, methods and uses
EP2295560A1 (en) 2009-09-14 2011-03-16 RWTH Aachen University Directed evolution of arginine deiminase for increased activity at physiological pH
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof

Also Published As

Publication number Publication date
BR112015021182A2 (pt) 2017-10-10
WO2014138319A2 (en) 2014-09-12
MX379135B (es) 2025-03-10
ES2909664T3 (es) 2022-05-09
TWI634212B (zh) 2018-09-01
CA2903152A1 (en) 2014-09-12
SG11201506679QA (en) 2015-09-29
US20160115468A1 (en) 2016-04-28
EA201500826A1 (ru) 2015-12-30
KR20150124999A (ko) 2015-11-06
CN105142663B (zh) 2017-12-08
EP2964761B1 (en) 2022-01-19
US9803185B2 (en) 2017-10-31
PH12015501995A1 (en) 2016-01-11
NZ711234A (en) 2021-01-29
PH12015501995B1 (en) 2016-01-11
CA2903152C (en) 2021-02-09
JP6243452B2 (ja) 2017-12-06
TW201520336A (zh) 2015-06-01
KR102139844B1 (ko) 2020-08-03
MY175144A (en) 2020-06-10
AU2014225712C1 (en) 2017-09-28
AU2014225712B2 (en) 2017-04-06
WO2014138319A3 (en) 2014-12-24
US9255262B2 (en) 2016-02-09
MX2015011578A (es) 2016-04-25
CL2015002479A1 (es) 2016-05-13
USRE47233E1 (en) 2019-02-12
EP2964761A4 (en) 2016-07-20
SA515360970B1 (ar) 2017-07-20
WO2014138319A8 (en) 2015-01-22
MA38376A1 (fr) 2017-10-31
EP2964761A2 (en) 2016-01-13
HK1211979A1 (en) 2016-06-03
AU2014225712A1 (en) 2015-09-10
MA38376B1 (fr) 2019-03-29
IL240976A0 (he) 2015-11-30
JP2016514111A (ja) 2016-05-19
IL240976A (he) 2016-09-29
EA036064B1 (ru) 2020-09-22
US20140255377A1 (en) 2014-09-11
CN105142663A (zh) 2015-12-09

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