AP2313A - Inhibitors of hepatitis C virus RNA-dependent RNA ploymerase, and compositions and treatments using the same. - Google Patents

Inhibitors of hepatitis C virus RNA-dependent RNA ploymerase, and compositions and treatments using the same.

Info

Publication number
AP2313A
AP2313A AP2007003918A AP2007003918A AP2313A AP 2313 A AP2313 A AP 2313A AP 2007003918 A AP2007003918 A AP 2007003918A AP 2007003918 A AP2007003918 A AP 2007003918A AP 2313 A AP2313 A AP 2313A
Authority
AP
ARIPO
Prior art keywords
rna
hepatitis
treatments
inhibitors
compositions
Prior art date
Application number
AP2007003918A
Other languages
English (en)
Other versions
AP2007003918A0 (en
Inventor
Javier Gonzalez
Tanya Michelle Jewell
Hui Li
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AP2007003918A0 publication Critical patent/AP2007003918A0/xx
Application granted granted Critical
Publication of AP2313A publication Critical patent/AP2313A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AP2007003918A 2004-08-18 2005-08-05 Inhibitors of hepatitis C virus RNA-dependent RNA ploymerase, and compositions and treatments using the same. AP2313A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60261804P 2004-08-18 2004-08-18
PCT/IB2005/002697 WO2006018725A1 (en) 2004-08-18 2005-08-05 Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same

Publications (2)

Publication Number Publication Date
AP2007003918A0 AP2007003918A0 (en) 2007-02-28
AP2313A true AP2313A (en) 2011-10-31

Family

ID=35429645

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2007003918A AP2313A (en) 2004-08-18 2005-08-05 Inhibitors of hepatitis C virus RNA-dependent RNA ploymerase, and compositions and treatments using the same.

Country Status (42)

Country Link
US (3) US7151105B2 (es)
EP (1) EP1781662B1 (es)
JP (1) JP4372195B2 (es)
KR (1) KR100851178B1 (es)
CN (2) CN101538268B (es)
AP (1) AP2313A (es)
AR (1) AR050699A1 (es)
AT (1) ATE506364T1 (es)
AU (1) AU2005273619B2 (es)
BR (1) BRPI0514425A (es)
CA (1) CA2577525C (es)
CR (2) CR8935A (es)
CY (1) CY1111480T1 (es)
DE (1) DE602005027580D1 (es)
DK (1) DK1781662T3 (es)
EA (1) EA012605B1 (es)
EC (1) ECSP077264A (es)
ES (1) ES2361845T3 (es)
GE (2) GEP20094751B (es)
GT (1) GT200500221A (es)
HN (1) HN2005000449A (es)
HR (1) HRP20110458T1 (es)
IL (2) IL180933A (es)
MA (1) MA28803B1 (es)
MX (1) MX2007001527A (es)
MY (1) MY146123A (es)
NI (1) NI200700043A (es)
NL (1) NL1029755C2 (es)
NO (1) NO20071274L (es)
NZ (1) NZ552874A (es)
PE (1) PE20060677A1 (es)
PL (1) PL1781662T3 (es)
PT (1) PT1781662E (es)
RS (1) RS51794B (es)
SI (1) SI1781662T1 (es)
SV (1) SV2007002202A (es)
TN (1) TNSN07066A1 (es)
TW (1) TWI376379B (es)
UA (1) UA88909C2 (es)
UY (1) UY29068A1 (es)
WO (1) WO2006018725A1 (es)
ZA (1) ZA200700779B (es)

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WO2018141961A1 (en) 2017-02-06 2018-08-09 Idorsia Pharmaceuticals Ltd A novel process for the synthesis of 1-aryl-1-trifluoromethylcyclopropanes
WO2019068572A1 (de) 2017-10-04 2019-04-11 Bayer Aktiengesellschaft Heterocyclen-derivate als schädlingsbekämpfungsmittel
CN111417630B (zh) 2017-10-05 2023-06-06 葛兰素史克知识产权开发有限公司 干扰素基因刺激因子(sting)的调节剂
EP3692033A1 (en) 2017-10-05 2020-08-12 GlaxoSmithKline Intellectual Property Development Limited Modulators of stimulator of interferon genes (sting) useful in treating hiv
WO2019175045A1 (de) 2018-03-12 2019-09-19 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
KR20210005081A (ko) 2018-04-20 2021-01-13 바이엘 악티엔게젤샤프트 해충 방제제로서의 헤테로시클렌 유도체
GB201807924D0 (en) 2018-05-16 2018-06-27 Ctxt Pty Ltd Compounds
TWI724753B (zh) 2019-01-25 2021-04-11 大陸商北京賽特明強醫藥科技有限公司 醯胺基橋連雜環類化合物、及其組合物與應用
CN114391015A (zh) 2019-05-16 2022-04-22 斯汀塞拉股份有限公司 苯并[b][1,8]萘啶乙酸衍生物和使用方法
CN114302875A (zh) 2019-05-16 2022-04-08 斯汀塞拉股份有限公司 氧代吖啶基乙酸衍生物及使用方法
GB201910304D0 (en) 2019-07-18 2019-09-04 Ctxt Pty Ltd Compounds
GB201910305D0 (en) 2019-07-18 2019-09-04 Ctxt Pty Ltd Compounds
CN114981265B (zh) 2019-12-18 2025-01-03 Ctxt私人有限公司 化合物
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Also Published As

Publication number Publication date
NZ552874A (en) 2010-04-30
EP1781662B1 (en) 2011-04-20
US8268835B2 (en) 2012-09-18
NL1029755A1 (nl) 2006-02-21
CR20110153A (es) 2011-04-26
ECSP077264A (es) 2007-04-26
PE20060677A1 (es) 2006-08-11
SI1781662T1 (sl) 2011-07-29
BRPI0514425A (pt) 2008-06-10
EA200700338A1 (ru) 2007-08-31
UA88909C2 (ru) 2009-12-10
US20070015764A1 (en) 2007-01-18
HN2005000449A (es) 2009-10-30
TNSN07066A1 (fr) 2008-06-02
AU2005273619B2 (en) 2009-05-28
TWI376379B (en) 2012-11-11
AP2007003918A0 (en) 2007-02-28
TW200612898A (en) 2006-05-01
DE602005027580D1 (de) 2011-06-01
RS51794B (sr) 2011-12-31
AR050699A1 (es) 2006-11-15
ES2361845T3 (es) 2011-06-22
US7622605B2 (en) 2009-11-24
AU2005273619A1 (en) 2006-02-23
ATE506364T1 (de) 2011-05-15
US7151105B2 (en) 2006-12-19
JP2008509984A (ja) 2008-04-03
MA28803B1 (fr) 2007-08-01
CN101538268A (zh) 2009-09-23
CY1111480T1 (el) 2015-08-05
KR20070044057A (ko) 2007-04-26
IL192919A0 (en) 2009-02-11
WO2006018725A1 (en) 2006-02-23
IL180933A0 (en) 2007-07-04
GEP20115305B (en) 2011-10-10
DK1781662T3 (da) 2011-06-27
GT200500221A (es) 2006-06-21
EA012605B1 (ru) 2009-10-30
UY29068A1 (es) 2006-03-31
HRP20110458T1 (hr) 2011-07-31
SV2007002202A (es) 2007-03-20
MX2007001527A (es) 2007-03-27
HK1109617A1 (en) 2008-06-13
CN101538268B (zh) 2011-07-27
EP1781662A1 (en) 2007-05-09
PT1781662E (pt) 2011-07-01
KR100851178B1 (ko) 2008-08-08
NI200700043A (es) 2008-01-02
GEP20094751B (en) 2009-08-10
CA2577525C (en) 2010-03-30
CR8935A (es) 2007-07-24
PL1781662T3 (pl) 2011-08-31
CN101006092B (zh) 2013-04-17
US20060122399A1 (en) 2006-06-08
CN101006092A (zh) 2007-07-25
IL180933A (en) 2011-08-31
NO20071274L (no) 2007-05-14
JP4372195B2 (ja) 2009-11-25
MY146123A (en) 2012-06-29
ZA200700779B (en) 2008-11-26
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