AP3199A - Agomelatine hydrobromide hadrate and preparation thereof - Google Patents

Agomelatine hydrobromide hadrate and preparation thereof

Info

Publication number: AP3199A
Authority: AP; ARIPO
Prior art keywords: hadrate; preparation; agomelatine hydrobromide; agomelatine; hydrobromide
Prior art date: 2010-03-17

Application number

AP2012006493A

Other languages

English (en)

Other versions

AP2012006493A0 (en

Inventor

Peng Zhang

Xueyan Zhu

Xiong Yu

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-03-17

Filing date

2011-03-17

Publication date

2015-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44599557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3199(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-03-17 Application filed by Servier Lab filed Critical Servier Lab

2012-10-31 Publication of AP2012006493A0 publication Critical patent/AP2012006493A0/xx

2015-03-31 Application granted granted Critical

2015-03-31 Publication of AP3199A publication Critical patent/AP3199A/xx

Links

CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 title 1
YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title 1
229960002629 agomelatine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Diabetes (AREA)
Anesthesiology (AREA)
Endocrinology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AP2012006493A 2010-03-17 2011-03-17 Agomelatine hydrobromide hadrate and preparation thereof AP3199A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CN2010101262639A CN102190595A (zh)	2010-03-17	2010-03-17	阿戈美拉汀溴化氢水合物及其制备方法
PCT/CN2011/071912 WO2011113363A1 (en)	2010-03-17	2011-03-17	Agomelatine hydrobromide hydrate and preparation thereof

Publications (2)

Publication Number	Publication Date
AP2012006493A0 AP2012006493A0 (en)	2012-10-31
AP3199A true AP3199A (en)	2015-03-31

Family

ID=44599557

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2012006493A AP3199A (en)	2010-03-17	2011-03-17	Agomelatine hydrobromide hadrate and preparation thereof

Country Status (39)

Country	Link
US (1)	US8729132B2 (xx)
EP (1)	EP2547650B1 (xx)
JP (1)	JP5634533B2 (xx)
KR (1)	KR101406736B1 (xx)
CN (2)	CN102190595A (xx)
AP (1)	AP3199A (xx)
AU (1)	AU2011229619B2 (xx)
BR (1)	BR112012023173B1 (xx)
CA (1)	CA2792430C (xx)
CL (1)	CL2012002541A1 (xx)
CR (1)	CR20120461A (xx)
CU (1)	CU20120136A7 (xx)
CY (1)	CY1117134T1 (xx)
DK (1)	DK2547650T3 (xx)
EA (1)	EA022066B1 (xx)
EC (1)	ECSP12012156A (xx)
ES (1)	ES2572427T3 (xx)
GE (1)	GEP20156232B (xx)
GT (1)	GT201200260A (xx)
HN (1)	HN2012001923A (xx)
HR (1)	HRP20151343T1 (xx)
HU (1)	HUE026673T2 (xx)
IL (1)	IL221783A (xx)
MA (1)	MA34054B1 (xx)
ME (1)	ME02309B (xx)
MX (1)	MX2012010594A (xx)
MY (1)	MY160337A (xx)
NI (1)	NI201200141A (xx)
NZ (1)	NZ602451A (xx)
PE (1)	PE20130014A1 (xx)
PH (1)	PH12012501756A1 (xx)
PL (1)	PL2547650T3 (xx)
PT (1)	PT2547650E (xx)
RS (1)	RS54449B1 (xx)
SG (1)	SG183869A1 (xx)
SI (1)	SI2547650T1 (xx)
TN (1)	TN2012000436A1 (xx)
UA (1)	UA105424C2 (xx)
WO (1)	WO2011113363A1 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07115742B2 (ja)	1986-03-19	1995-12-13	株式会社石田衡器製作所	多方向仕分け装置
JPH07115739B2 (ja)	1986-03-19	1995-12-13	株式会社石田衡器製作所	多方向仕分け装置
JPH07115740B2 (ja)	1986-03-19	1995-12-13	株式会社石田衡器製作所	多方向仕分け装置
JPH07115741B2 (ja)	1986-03-19	1995-12-13	株式会社石田衡器製作所	多方向仕分け装置
FR2978916B1 (fr)	2011-08-10	2013-07-26	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
EP2851363B1 (en) *	2012-05-14	2018-01-03	Shanghai Righthand Pharmtech. Co., Ltd.	Agomelatine acid radical composite, and preparation method and application thereof
CN102718675B (zh) *	2012-06-07	2015-03-25	上海右手医药科技开发有限公司	阿戈美拉汀甲磺酸复合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2658818B1 (fr) *	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20020107275A1 (en) *	2000-10-30	2002-08-08	Ramy Lidor-Hadas	Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation
FR2890562B1 (fr) *	2005-09-09	2012-10-12	Servier Lab	Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles du sommeil chez le patient deprime
FR2899472B1 (fr) *	2006-04-07	2008-09-12	Servier Lab	Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee
CN101481321B (zh) *	2009-02-27	2012-04-18	上海医药工业研究院	阿戈美拉汀卤化氢复合物及其制备方法
CN101585779B (zh) *	2009-03-10	2014-04-02	上海医药工业研究院	阿戈美拉汀的晶型vi及其制备方法和应用

2010
- 2010-03-17 CN CN2010101262639A patent/CN102190595A/zh active Pending
2011
- 2011-03-17 UA UAA201211719A patent/UA105424C2/uk unknown
- 2011-03-17 US US13/635,087 patent/US8729132B2/en active Active
- 2011-03-17 SI SI201130723T patent/SI2547650T1/sl unknown
- 2011-03-17 WO PCT/CN2011/071912 patent/WO2011113363A1/en not_active Ceased
- 2011-03-17 PL PL11755680T patent/PL2547650T3/pl unknown
- 2011-03-17 CN CN201180024413.8A patent/CN102892749B/zh not_active Expired - Fee Related
- 2011-03-17 MX MX2012010594A patent/MX2012010594A/es active IP Right Grant
- 2011-03-17 ES ES11755680T patent/ES2572427T3/es active Active
- 2011-03-17 HR HRP20151343TT patent/HRP20151343T1/hr unknown
- 2011-03-17 KR KR1020127026897A patent/KR101406736B1/ko not_active Expired - Fee Related
- 2011-03-17 BR BR112012023173-1A patent/BR112012023173B1/pt not_active IP Right Cessation
- 2011-03-17 PE PE2012001449A patent/PE20130014A1/es active IP Right Grant
- 2011-03-17 SG SG2012065017A patent/SG183869A1/en unknown
- 2011-03-17 MA MA35191A patent/MA34054B1/fr unknown
- 2011-03-17 PT PT117556803T patent/PT2547650E/pt unknown
- 2011-03-17 EP EP11755680.3A patent/EP2547650B1/en active Active
- 2011-03-17 AP AP2012006493A patent/AP3199A/xx active
- 2011-03-17 DK DK11755680.3T patent/DK2547650T3/en active
- 2011-03-17 AU AU2011229619A patent/AU2011229619B2/en not_active Ceased
- 2011-03-17 RS RS20150831A patent/RS54449B1/sr unknown
- 2011-03-17 CA CA2792430A patent/CA2792430C/en active Active
- 2011-03-17 MY MYPI2012700614A patent/MY160337A/en unknown
- 2011-03-17 ME MEP-2016-9A patent/ME02309B/me unknown
- 2011-03-17 JP JP2012557393A patent/JP5634533B2/ja not_active Expired - Fee Related
- 2011-03-17 NZ NZ602451A patent/NZ602451A/en not_active IP Right Cessation
- 2011-03-17 GE GEAP201112870A patent/GEP20156232B/en unknown
- 2011-03-17 EA EA201201293A patent/EA022066B1/ru unknown
- 2011-03-17 PH PH1/2012/501756A patent/PH12012501756A1/en unknown
- 2011-03-17 HU HUE11755680A patent/HUE026673T2/en unknown
2012
- 2012-08-31 TN TNP2012000436A patent/TN2012000436A1/en unknown
- 2012-09-04 IL IL221783A patent/IL221783A/en not_active IP Right Cessation
- 2012-09-11 CR CR20120461A patent/CR20120461A/es unknown
- 2012-09-12 NI NI201200141A patent/NI201200141A/es unknown
- 2012-09-13 CL CL2012002541A patent/CL2012002541A1/es unknown
- 2012-09-14 HN HN2012001923A patent/HN2012001923A/es unknown
- 2012-09-14 EC ECSP12012156 patent/ECSP12012156A/es unknown
- 2012-09-17 GT GT201200260A patent/GT201200260A/es unknown
- 2012-09-17 CU CU2012000136A patent/CU20120136A7/es unknown
2016
- 2016-01-18 CY CY20161100041T patent/CY1117134T1/el unknown

Also Published As

Publication number	Publication date
EP2547650B1 (en)	2015-11-04
ME02309B (me)	2016-06-20
IL221783A (en)	2017-11-30
NZ602451A (en)	2014-10-31
HRP20151343T1 (hr)	2016-01-01
HN2012001923A (es)	2015-09-14
RS54449B1 (sr)	2016-06-30
CN102892749B (zh)	2014-11-05
PT2547650E (pt)	2015-11-30
JP5634533B2 (ja)	2014-12-03
PE20130014A1 (es)	2013-01-26
UA105424C2 (uk)	2014-05-12
GEP20156232B (en)	2015-01-26
NI201200141A (es)	2012-11-09
CA2792430A1 (en)	2011-09-22
SG183869A1 (en)	2012-10-30
AU2011229619A1 (en)	2012-09-27
SI2547650T1 (sl)	2016-02-29
ECSP12012156A (es)	2012-12-28
US20130012592A1 (en)	2013-01-10
GT201200260A (es)	2013-11-18
ES2572427T3 (es)	2016-05-31
TN2012000436A1 (en)	2014-01-30
CR20120461A (es)	2012-11-29
EP2547650A1 (en)	2013-01-23
HK1177732A1 (en)	2013-08-30
AU2011229619B2 (en)	2014-05-22
MX2012010594A (es)	2012-10-03
DK2547650T3 (en)	2016-02-15
JP2013522242A (ja)	2013-06-13
AP2012006493A0 (en)	2012-10-31
EA022066B1 (ru)	2015-10-30
PH12012501756A1 (en)	2012-11-12
KR101406736B1 (ko)	2014-06-12
CN102892749A (zh)	2013-01-23
BR112012023173B1 (pt)	2021-08-24
PL2547650T3 (pl)	2016-06-30
KR20120128713A (ko)	2012-11-27
MY160337A (en)	2017-02-28
CU20120136A7 (es)	2012-12-17
EA201201293A1 (ru)	2013-04-30
EP2547650A4 (en)	2013-09-18
CA2792430C (en)	2015-12-08
BR112012023173A2 (pt)	2016-05-17
WO2011113363A1 (en)	2011-09-22
HUE026673T2 (en)	2016-07-28
US8729132B2 (en)	2014-05-20
MA34054B1 (fr)	2013-03-05
CY1117134T1 (el)	2017-04-05
CN102190595A (zh)	2011-09-21
CL2012002541A1 (es)	2013-01-11

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