AP3589A - A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes - Google Patents

A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes

Info

Publication number
AP3589A
AP3589A AP2014007436A AP2014007436A AP3589A AP 3589 A AP3589 A AP 3589A AP 2014007436 A AP2014007436 A AP 2014007436A AP 2014007436 A AP2014007436 A AP 2014007436A AP 3589 A AP3589 A AP 3589A
Authority
AP
ARIPO
Prior art keywords
diabetes
novel
treatment
derivative useful
tetrahydroquinoline derivative
Prior art date
Application number
AP2014007436A
Other languages
English (en)
Other versions
AP2014007436A0 (en
Inventor
Chafiq Hamdouchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3589(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AP2014007436A0 publication Critical patent/AP2014007436A0/xx
Application granted granted Critical
Publication of AP3589A publication Critical patent/AP3589A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2014007436A 2011-08-17 2012-08-09 A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes AP3589A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161524462P 2011-08-17 2011-08-17
PCT/US2012/050051 WO2013025424A1 (fr) 2011-08-17 2012-08-09 Nouveau dérivé de 1,2,3,4-tetrahydroquinoline utile dans le traitement du diabète

Publications (2)

Publication Number Publication Date
AP2014007436A0 AP2014007436A0 (en) 2014-02-28
AP3589A true AP3589A (en) 2016-02-15

Family

ID=46690732

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2014007436A AP3589A (en) 2011-08-17 2012-08-09 A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes

Country Status (30)

Country Link
US (1) US8431706B2 (fr)
EP (1) EP2744806B1 (fr)
JP (1) JP5903162B2 (fr)
KR (1) KR101570624B1 (fr)
CN (1) CN103687856B (fr)
AP (1) AP3589A (fr)
AR (1) AR087451A1 (fr)
AU (1) AU2012295372A1 (fr)
BR (1) BR112014003079A2 (fr)
CA (1) CA2843474C (fr)
CL (1) CL2014000357A1 (fr)
CO (1) CO6880069A2 (fr)
CR (1) CR20140052A (fr)
DO (1) DOP2014000018A (fr)
EA (1) EA022165B1 (fr)
EC (1) ECSP14013211A (fr)
ES (1) ES2578165T3 (fr)
GT (1) GT201400022A (fr)
IL (1) IL230635A (fr)
IN (1) IN2014MN00191A (fr)
MA (1) MA35351B1 (fr)
MX (1) MX2014001832A (fr)
PE (1) PE20140831A1 (fr)
PH (1) PH12014500366A1 (fr)
SG (1) SG11201401793PA (fr)
TN (1) TN2014000058A1 (fr)
TW (1) TWI537262B (fr)
UA (1) UA110983C2 (fr)
WO (1) WO2013025424A1 (fr)
ZA (1) ZA201400705B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3068788A1 (fr) 2013-11-14 2016-09-21 Cadila Healthcare Limited Nouveaux composés hétérocycliques
EP3076959B1 (fr) 2013-12-04 2018-07-04 Merck Sharp & Dohme Corp. Composés bicycliques antidiabétiques
US10059667B2 (en) 2014-02-06 2018-08-28 Merck Sharp & Dohme Corp. Antidiabetic compounds
BR102018007822A2 (pt) 2017-04-20 2018-11-06 Gilead Sciences, Inc. composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
CN109666027A (zh) * 2017-10-17 2019-04-23 中国科学院上海药物研究所 一类酰胺结构的gpr40激动剂化合物及其用途
WO2019134984A1 (fr) 2018-01-08 2019-07-11 Celon Pharma S.A. Dérivés d'acides 3-phényl-4-hexinoïques en tant qu'agonistes de gpr40
KR102708681B1 (ko) 2018-02-13 2024-09-26 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
EP4600247A3 (fr) 2018-04-19 2025-11-19 Gilead Sciences, Inc. Inhibiteurs de pd-1/pd-l1
UA126421C2 (uk) 2018-07-13 2022-09-28 Гіліад Сайєнсіз, Інк. Інгібітори pd-1/pd-l1
US11236085B2 (en) 2018-10-24 2022-02-01 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
WO2020242252A1 (fr) 2019-05-31 2020-12-03 현대약품 주식회사 Nouvelle forme cristalline d'un dérivé d'acide 3-(4-(benzyloxy)phényl)hex-4-inoïque
TWI751585B (zh) * 2019-06-28 2022-01-01 美商美國禮來大藥廠 類升糖素肽1受體促效劑
BR112022006546A2 (pt) 2019-10-07 2022-08-30 Kallyope Inc Agonistas de gpr119
WO2021083270A1 (fr) * 2019-10-31 2021-05-06 中国石油化工股份有限公司 Catalyseur supporté, son procédé de préparation et son application
CA3173731A1 (fr) 2020-02-28 2021-09-02 Kallyope, Inc. Agonistes de gpr40
CN116323608A (zh) 2020-05-19 2023-06-23 卡尔优普公司 Ampk活化剂
EP4172162A4 (fr) 2020-06-26 2024-08-07 Kallyope, Inc. Activateurs d'ampk
KR102699076B1 (ko) * 2021-04-01 2024-08-27 현대약품 주식회사 3-(4-(벤질옥시)페닐)헥스-4-이노익산 유도체의 신규 용도
CN115317484B (zh) * 2022-08-26 2023-07-18 北京箭牧科技有限公司 Ly2922470在制备预防或治疗脑血管疾病或组织缺血再灌注损伤药物中的应用
CN115671105B (zh) * 2022-11-22 2023-10-27 北京箭牧科技有限公司 Ly2922470在制备预防或治疗肾脏疾病药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004012A1 (en) * 2004-02-27 2006-01-05 Michelle Akerman Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
WO2011066183A1 (fr) * 2009-11-30 2011-06-03 Eli Lilly And Company Nouveau composé de spiropipéridine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT199900147A (es) * 1998-09-17 1999-09-06 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
EP1379523B1 (fr) * 2001-03-27 2005-07-27 Actelion Pharmaceuticals Ltd. Derives de 1,2,3,4-tetrahydro-isoquinoline en tant qu'antagonistes du recepteur de l'urotensine ii
WO2005087710A1 (fr) * 2004-03-15 2005-09-22 Takeda Pharmaceutical Company Limited Dérivé de l'acide aminophénylpropanoïque
EP2253315A1 (fr) * 2004-03-30 2010-11-24 Takeda Pharmaceutical Company Limited Dérivés d'acide alkoxypropanoique
AR078522A1 (es) 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060004012A1 (en) * 2004-02-27 2006-01-05 Michelle Akerman Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
WO2011066183A1 (fr) * 2009-11-30 2011-06-03 Eli Lilly And Company Nouveau composé de spiropipéridine

Also Published As

Publication number Publication date
KR101570624B1 (ko) 2015-11-19
CL2014000357A1 (es) 2014-09-05
US8431706B2 (en) 2013-04-30
JP5903162B2 (ja) 2016-04-13
IL230635A (en) 2015-11-30
WO2013025424A1 (fr) 2013-02-21
SG11201401793PA (en) 2014-09-26
EP2744806B1 (fr) 2016-04-27
EA022165B1 (ru) 2015-11-30
KR20140041835A (ko) 2014-04-04
TW201319060A (zh) 2013-05-16
UA110983C2 (uk) 2016-03-10
TN2014000058A1 (en) 2015-07-01
ES2578165T3 (es) 2016-07-21
EA201490269A1 (ru) 2014-05-30
CN103687856B (zh) 2015-07-22
PE20140831A1 (es) 2014-07-14
ZA201400705B (en) 2015-11-25
GT201400022A (es) 2015-01-16
MX2014001832A (es) 2014-02-27
CO6880069A2 (es) 2014-02-28
AP2014007436A0 (en) 2014-02-28
BR112014003079A2 (pt) 2017-02-21
US20130045990A1 (en) 2013-02-21
NZ621248A (en) 2015-08-28
CR20140052A (es) 2014-06-20
IN2014MN00191A (fr) 2015-08-21
CA2843474C (fr) 2015-12-15
EP2744806A1 (fr) 2014-06-25
PH12014500366A1 (en) 2014-04-14
IL230635A0 (en) 2014-03-31
CA2843474A1 (fr) 2013-02-21
MA35351B1 (fr) 2014-08-01
JP2014521744A (ja) 2014-08-28
DOP2014000018A (es) 2014-04-15
ECSP14013211A (es) 2014-03-31
AR087451A1 (es) 2014-03-26
AU2012295372A1 (en) 2014-01-23
TWI537262B (zh) 2016-06-11
CN103687856A (zh) 2014-03-26

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