AP732A - Substances extracted from dictyotales, preparation method therefor, and compositions containing same. - Google Patents

Substances extracted from dictyotales, preparation method therefor, and compositions containing same. Download PDF

Info

Publication number: AP732A
Authority: AP; ARIPO
Prior art keywords: active substances; substances according; biologically; biologically active; dictyotales
Prior art date: 1996-01-18

Application number

APAP/P/1997/001085A

Other languages

English (en)

Other versions

AP9701085A0 (en

Inventor

Gilles Gutierrez

Original Assignee

Texinfine Sa

Laboratoires Laphal S A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-18

Filing date

1997-01-20

Publication date

1999-02-10

1997-01-20 Application filed by Texinfine Sa, Laboratoires Laphal S A filed Critical Texinfine Sa

1997-10-31 Publication of AP9701085A0 publication Critical patent/AP9701085A0/xx

1999-02-10 Application granted granted Critical

1999-02-10 Publication of AP732A publication Critical patent/AP732A/en

Links

239000000203 mixture Substances 0.000 title claims abstract description 54
241000199916 Dictyotales Species 0.000 title claims abstract description 44
239000000126 substance Substances 0.000 title claims abstract description 38
238000002360 preparation method Methods 0.000 title description 3
239000013543 active substance Substances 0.000 claims abstract description 83
238000003786 synthesis reaction Methods 0.000 claims abstract description 33
102000010834 Extracellular Matrix Proteins Human genes 0.000 claims abstract description 28
108010037362 Extracellular Matrix Proteins Proteins 0.000 claims abstract description 28
210000002744 extracellular matrix Anatomy 0.000 claims abstract description 28
230000015572 biosynthetic process Effects 0.000 claims abstract description 26
210000001519 tissue Anatomy 0.000 claims abstract description 19
241001465754 Metazoa Species 0.000 claims abstract description 17
239000000284 extract Substances 0.000 claims abstract description 12
238000000034 method Methods 0.000 claims abstract description 11
239000002537 cosmetic Substances 0.000 claims abstract description 9
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 40
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 36
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 30
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 24
239000002904 solvent Substances 0.000 claims description 19
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 18
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 18
239000000377 silicon dioxide Substances 0.000 claims description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 16
230000014759 maintenance of location Effects 0.000 claims description 15
239000003480 eluent Substances 0.000 claims description 14
238000000605 extraction Methods 0.000 claims description 12
238000000746 purification Methods 0.000 claims description 12
239000001117 sulphuric acid Substances 0.000 claims description 12
102000016611 Proteoglycans Human genes 0.000 claims description 11
108010067787 Proteoglycans Proteins 0.000 claims description 11
239000003960 organic solvent Substances 0.000 claims description 11
229920002683 Glycosaminoglycan Polymers 0.000 claims description 10
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 9
238000004587 chromatography analysis Methods 0.000 claims description 9
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 8
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 8
IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims description 8
239000007788 liquid Substances 0.000 claims description 8
239000004480 active ingredient Substances 0.000 claims description 7
238000001035 drying Methods 0.000 claims description 7
238000004128 high performance liquid chromatography Methods 0.000 claims description 7
238000002953 preparative HPLC Methods 0.000 claims description 7
230000008569 process Effects 0.000 claims description 7
238000004809 thin layer chromatography Methods 0.000 claims description 7
-1 phophomolybdate Substances 0.000 claims description 6
238000001704 evaporation Methods 0.000 claims description 5
230000008020 evaporation Effects 0.000 claims description 5
229910052500 inorganic mineral Inorganic materials 0.000 claims description 5
239000011707 mineral Substances 0.000 claims description 5
230000000699 topical effect Effects 0.000 claims description 5
230000000295 complement effect Effects 0.000 claims description 4
238000010521 absorption reaction Methods 0.000 claims description 3
239000002253 acid Substances 0.000 claims description 3
150000001335 aliphatic alkanes Chemical class 0.000 claims description 3
125000004432 carbon atom Chemical group C* 0.000 claims description 3
231100000252 nontoxic Toxicity 0.000 claims description 3
230000003000 nontoxic effect Effects 0.000 claims description 3
125000003367 polycyclic group Chemical group 0.000 claims description 3
238000002211 ultraviolet spectrum Methods 0.000 claims description 3
239000003849 aromatic solvent Substances 0.000 claims description 2
150000001924 cycloalkanes Chemical class 0.000 claims description 2
230000001079 digestive effect Effects 0.000 claims description 2
150000002148 esters Chemical class 0.000 claims description 2
150000002170 ethers Chemical class 0.000 claims description 2
238000000227 grinding Methods 0.000 claims description 2
239000011368 organic material Substances 0.000 claims description 2
235000013311 vegetables Nutrition 0.000 claims 4
150000002009 diols Chemical class 0.000 claims 1
235000013305 food Nutrition 0.000 abstract description 3
241000196324 Embryophyta Species 0.000 description 59
210000002950 fibroblast Anatomy 0.000 description 23
210000004027 cell Anatomy 0.000 description 22
230000000694 effects Effects 0.000 description 22
102000000589 Interleukin-1 Human genes 0.000 description 17
108010002352 Interleukin-1 Proteins 0.000 description 17
210000001612 chondrocyte Anatomy 0.000 description 16
239000002609 medium Substances 0.000 description 15
238000009472 formulation Methods 0.000 description 12
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 11
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 10
210000000988 bone and bone Anatomy 0.000 description 10
229920002674 hyaluronan Polymers 0.000 description 10
229960003160 hyaluronic acid Drugs 0.000 description 10
239000000243 solution Substances 0.000 description 10
239000000499 gel Substances 0.000 description 9
210000000963 osteoblast Anatomy 0.000 description 9
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 8
229920001223 polyethylene glycol Polymers 0.000 description 8
239000000843 powder Substances 0.000 description 8
210000003491 skin Anatomy 0.000 description 8
239000005418 vegetable material Substances 0.000 description 8
239000002202 Polyethylene glycol Substances 0.000 description 7
230000009471 action Effects 0.000 description 7
239000002775 capsule Substances 0.000 description 7
239000001913 cellulose Substances 0.000 description 7
229920002678 cellulose Polymers 0.000 description 7
235000010980 cellulose Nutrition 0.000 description 7
210000000845 cartilage Anatomy 0.000 description 6
210000002510 keratinocyte Anatomy 0.000 description 6
239000000463 material Substances 0.000 description 6
235000011149 sulphuric acid Nutrition 0.000 description 6
239000003826 tablet Substances 0.000 description 6
230000001413 cellular effect Effects 0.000 description 5
239000003795 chemical substances by application Substances 0.000 description 5
235000016709 nutrition Nutrition 0.000 description 5
230000002265 prevention Effects 0.000 description 5
239000002356 single layer Substances 0.000 description 5
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 4
238000004458 analytical method Methods 0.000 description 4
229910000019 calcium carbonate Inorganic materials 0.000 description 4
239000000839 emulsion Substances 0.000 description 4
238000004264 monolayer culture Methods 0.000 description 4
230000000144 pharmacologic effect Effects 0.000 description 4
241000894007 species Species 0.000 description 4
241000238557 Decapoda Species 0.000 description 3
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
229920002125 Sokalan® Polymers 0.000 description 3
239000002250 absorbent Substances 0.000 description 3
230000002745 absorbent Effects 0.000 description 3
239000012620 biological material Substances 0.000 description 3
229940088623 biologically active substance Drugs 0.000 description 3
239000008119 colloidal silica Substances 0.000 description 3
239000006071 cream Substances 0.000 description 3
230000002939 deleterious effect Effects 0.000 description 3
210000002615 epidermis Anatomy 0.000 description 3
239000007943 implant Substances 0.000 description 3
230000004048 modification Effects 0.000 description 3
238000012986 modification Methods 0.000 description 3
239000000546 pharmaceutical excipient Substances 0.000 description 3
229920000642 polymer Polymers 0.000 description 3
239000003755 preservative agent Substances 0.000 description 3
238000011158 quantitative evaluation Methods 0.000 description 3
230000004044 response Effects 0.000 description 3
230000000638 stimulation Effects 0.000 description 3
238000001356 surgical procedure Methods 0.000 description 3
OEANUJAFZLQYOD-CXAZCLJRSA-N (2r,3s,4r,5r,6r)-6-[(2r,3r,4r,5r,6r)-5-acetamido-3-hydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](OC)O[C@H](CO)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](OC)[C@H](C(O)=O)O1 OEANUJAFZLQYOD-CXAZCLJRSA-N 0.000 description 2
OKMWKBLSFKFYGZ-UHFFFAOYSA-N 1-behenoylglycerol Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(O)CO OKMWKBLSFKFYGZ-UHFFFAOYSA-N 0.000 description 2
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
241000238421 Arthropoda Species 0.000 description 2
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
229920002567 Chondroitin Polymers 0.000 description 2
XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 2
229920000045 Dermatan sulfate Polymers 0.000 description 2
241000030950 Padina Species 0.000 description 2
OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 2
239000002671 adjuvant Substances 0.000 description 2
230000008901 benefit Effects 0.000 description 2
238000012822 chemical development Methods 0.000 description 2
DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 description 2
230000007850 degeneration Effects 0.000 description 2
AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 2
238000010790 dilution Methods 0.000 description 2
239000012895 dilution Substances 0.000 description 2
239000008298 dragée Substances 0.000 description 2
235000013601 eggs Nutrition 0.000 description 2
238000010828 elution Methods 0.000 description 2
230000037406 food intake Effects 0.000 description 2
239000012634 fragment Substances 0.000 description 2
238000004108 freeze drying Methods 0.000 description 2
239000003102 growth factor Substances 0.000 description 2
230000035876 healing Effects 0.000 description 2
239000005556 hormone Substances 0.000 description 2
229940088597 hormone Drugs 0.000 description 2
230000006872 improvement Effects 0.000 description 2
238000011534 incubation Methods 0.000 description 2
239000002502 liposome Substances 0.000 description 2
238000002803 maceration Methods 0.000 description 2
239000012528 membrane Substances 0.000 description 2
238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 2
239000002674 ointment Substances 0.000 description 2
ZRSNZINYAWTAHE-UHFFFAOYSA-N p-methoxybenzaldehyde Chemical compound COC1=CC=C(C=O)C=C1 ZRSNZINYAWTAHE-UHFFFAOYSA-N 0.000 description 2
239000002798 polar solvent Substances 0.000 description 2
230000002335 preservative effect Effects 0.000 description 2
235000013772 propylene glycol Nutrition 0.000 description 2
102000004169 proteins and genes Human genes 0.000 description 2
108090000623 proteins and genes Proteins 0.000 description 2
230000028327 secretion Effects 0.000 description 2
239000007787 solid Substances 0.000 description 2
239000000758 substrate Substances 0.000 description 2
239000000725 suspension Substances 0.000 description 2
210000002437 synoviocyte Anatomy 0.000 description 2
230000009885 systemic effect Effects 0.000 description 2
239000000454 talc Substances 0.000 description 2
229910052623 talc Inorganic materials 0.000 description 2
238000012360 testing method Methods 0.000 description 2
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 2
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 2
235000012141 vanillin Nutrition 0.000 description 2
239000003981 vehicle Substances 0.000 description 2
238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 1
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
229910002012 Aerosil® Inorganic materials 0.000 description 1
102000016284 Aggrecans Human genes 0.000 description 1
108010067219 Aggrecans Proteins 0.000 description 1
102000004954 Biglycan Human genes 0.000 description 1
108090001138 Biglycan Proteins 0.000 description 1
235000014653 Carica parviflora Nutrition 0.000 description 1
241000243321 Cnidaria Species 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
102000004127 Cytokines Human genes 0.000 description 1
108090000695 Cytokines Proteins 0.000 description 1
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
102000004237 Decorin Human genes 0.000 description 1
108090000738 Decorin Proteins 0.000 description 1
241000199924 Dictyota Species 0.000 description 1
241000199915 Dictyotaceae Species 0.000 description 1
239000006144 Dulbecco’s modiﬁed Eagle's medium Substances 0.000 description 1
239000004150 EU approved colour Substances 0.000 description 1
241000258955 Echinodermata Species 0.000 description 1
102000004190 Enzymes Human genes 0.000 description 1
108090000790 Enzymes Proteins 0.000 description 1
102000017177 Fibromodulin Human genes 0.000 description 1
108010013996 Fibromodulin Proteins 0.000 description 1
229920000926 Galactomannan Polymers 0.000 description 1
239000001828 Gelatine Substances 0.000 description 1
102000010956 Glypican Human genes 0.000 description 1
108050001154 Glypican Proteins 0.000 description 1
241001112262 Gymnospora Species 0.000 description 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
241000282412 Homo Species 0.000 description 1
102000015696 Interleukins Human genes 0.000 description 1
108010063738 Interleukins Proteins 0.000 description 1
241000124008 Mammalia Species 0.000 description 1
229920000057 Mannan Polymers 0.000 description 1
229920000168 Microcrystalline cellulose Polymers 0.000 description 1
241000237852 Mollusca Species 0.000 description 1
241000030972 Padina tenuis Species 0.000 description 1
208000037273 Pathologic Processes Diseases 0.000 description 1
241000199919 Phaeophyceae Species 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
102000019361 Syndecan Human genes 0.000 description 1
108050006774 Syndecan Proteins 0.000 description 1
108090000054 Syndecan-2 Proteins 0.000 description 1
102000003711 Syndecan-2 Human genes 0.000 description 1
102100033663 Transforming growth factor beta receptor type 3 Human genes 0.000 description 1
241000209140 Triticum Species 0.000 description 1
235000021307 Triticum Nutrition 0.000 description 1
229930003268 Vitamin C Natural products 0.000 description 1
238000002441 X-ray diffraction Methods 0.000 description 1
241001627080 Zonaria <gastropod> Species 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000003213 activating effect Effects 0.000 description 1
239000002156 adsorbate Substances 0.000 description 1
239000000783 alginic acid Substances 0.000 description 1
235000010443 alginic acid Nutrition 0.000 description 1
229920000615 alginic acid Polymers 0.000 description 1
229960001126 alginic acid Drugs 0.000 description 1
150000004781 alginic acids Chemical class 0.000 description 1
239000012736 aqueous medium Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
239000007900 aqueous suspension Substances 0.000 description 1
108010079292 betaglycan Proteins 0.000 description 1
238000009395 breeding Methods 0.000 description 1
230000001488 breeding effect Effects 0.000 description 1
239000001506 calcium phosphate Substances 0.000 description 1
229910000389 calcium phosphate Inorganic materials 0.000 description 1
235000011010 calcium phosphates Nutrition 0.000 description 1
FVMOEFABYNPCDS-UHFFFAOYSA-L calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate Chemical compound [Ca+2].CCC([O-])=C1C(=O)CC(C(O)=O)CC1=O.CCC([O-])=C1C(=O)CC(C(O)=O)CC1=O FVMOEFABYNPCDS-UHFFFAOYSA-L 0.000 description 1
244000309466 calf Species 0.000 description 1
229960001631 carbomer Drugs 0.000 description 1
238000012512 characterization method Methods 0.000 description 1
239000003153 chemical reaction reagent Substances 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
239000000084 colloidal system Substances 0.000 description 1
238000004040 coloring Methods 0.000 description 1
238000004440 column chromatography Methods 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
210000002808 connective tissue Anatomy 0.000 description 1
239000000470 constituent Substances 0.000 description 1
230000006378 damage Effects 0.000 description 1
238000004200 deflagration Methods 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
210000004207 dermis Anatomy 0.000 description 1
238000001514 detection method Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
230000018109 developmental process Effects 0.000 description 1
235000005911 diet Nutrition 0.000 description 1
230000000378 dietary effect Effects 0.000 description 1
XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 1
238000002050 diffraction method Methods 0.000 description 1
238000009792 diffusion process Methods 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
230000005684 electric field Effects 0.000 description 1
238000001962 electrophoresis Methods 0.000 description 1
230000001804 emulsifying effect Effects 0.000 description 1
210000002919 epithelial cell Anatomy 0.000 description 1
229930182833 estradiol Natural products 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
238000011049 filling Methods 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000019634 flavors Nutrition 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
229930182470 glycoside Natural products 0.000 description 1
150000002338 glycosides Chemical class 0.000 description 1
239000001963 growth medium Substances 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
230000012447 hatching Effects 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
229920000669 heparin Polymers 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
230000003054 hormonal effect Effects 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
239000008309 hydrophilic cream Substances 0.000 description 1
229910052588 hydroxylapatite Inorganic materials 0.000 description 1
239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
238000010166 immunofluorescence Methods 0.000 description 1
238000011065 in-situ storage Methods 0.000 description 1
238000002329 infrared spectrum Methods 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
229940047122 interleukins Drugs 0.000 description 1
210000001503 joint Anatomy 0.000 description 1
239000010410 layer Substances 0.000 description 1
230000003902 lesion Effects 0.000 description 1
239000006210 lotion Substances 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
LUEWUZLMQUOBSB-GFVSVBBRSA-N mannan Chemical class O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-GFVSVBBRSA-N 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
238000001819 mass spectrum Methods 0.000 description 1
239000011159 matrix material Substances 0.000 description 1
230000035800 maturation Effects 0.000 description 1
235000012054 meals Nutrition 0.000 description 1
XELZGAJCZANUQH-UHFFFAOYSA-N methyl 1-acetylthieno[3,2-c]pyrazole-5-carboxylate Chemical compound CC(=O)N1N=CC2=C1C=C(C(=O)OC)S2 XELZGAJCZANUQH-UHFFFAOYSA-N 0.000 description 1
235000019813 microcrystalline cellulose Nutrition 0.000 description 1
239000008108 microcrystalline cellulose Substances 0.000 description 1
229940016286 microcrystalline cellulose Drugs 0.000 description 1
DIOQZVSQGTUSAI-UHFFFAOYSA-N n-butylhexane Natural products CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 description 1
239000002088 nanocapsule Substances 0.000 description 1
239000002077 nanosphere Substances 0.000 description 1
235000015097 nutrients Nutrition 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
230000000050 nutritive effect Effects 0.000 description 1
229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
238000006213 oxygenation reaction Methods 0.000 description 1
230000009054 pathological process Effects 0.000 description 1
239000008188 pellet Substances 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
238000005325 percolation Methods 0.000 description 1
239000008194 pharmaceutical composition Substances 0.000 description 1
239000006187 pill Substances 0.000 description 1
229920000747 poly(lactic acid) Polymers 0.000 description 1
239000004584 polyacrylic acid Substances 0.000 description 1
239000004626 polylactic acid Substances 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
230000002980 postoperative effect Effects 0.000 description 1
230000001376 precipitating effect Effects 0.000 description 1
238000012746 preparative thin layer chromatography Methods 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
230000000384 rearing effect Effects 0.000 description 1
230000008929 regeneration Effects 0.000 description 1
238000011069 regeneration method Methods 0.000 description 1
210000002966 serum Anatomy 0.000 description 1
235000015170 shellfish Nutrition 0.000 description 1
238000002798 spectrophotometry method Methods 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
230000006641 stabilisation Effects 0.000 description 1
238000011105 stabilization Methods 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
230000004936 stimulating effect Effects 0.000 description 1
239000007940 sugar coated tablet Substances 0.000 description 1
239000000829 suppository Substances 0.000 description 1
230000004083 survival effect Effects 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
238000009423 ventilation Methods 0.000 description 1
235000019154 vitamin C Nutrition 0.000 description 1
239000011718 vitamin C Substances 0.000 description 1
239000011647 vitamin D3 Substances 0.000 description 1
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
238000001262 western blot Methods 0.000 description 1
229920001285 xanthan gum Polymers 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
- A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K61/00—Culture of aquatic animals
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/60—Edible seaweed
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/202—Algae extracts
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Biotechnology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Natural Medicines & Medicinal Plants (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Botany (AREA)
Mycology (AREA)
Microbiology (AREA)
Medical Informatics (AREA)
Alternative & Traditional Medicine (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
Nutrition Science (AREA)
Zoology (AREA)
Marine Sciences & Fisheries (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Birds (AREA)
Molecular Biology (AREA)
Environmental Sciences (AREA)
Obesity (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Animal Husbandry (AREA)
Biodiversity & Conservation Biology (AREA)
Hematology (AREA)
Medicines Containing Plant Substances (AREA)

APAP/P/1997/001085A 1996-01-18 1997-01-20 Substances extracted from dictyotales, preparation method therefor, and compositions containing same. AP732A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9600522A FR2743723B1 (fr)	1996-01-18	1996-01-18	Utilisation d'extrait des plantes de la famille des dictyotales en vue de la realisation de preparations destinees a remanier les elements glycosyles de la matrice extracellulaire de tissus vivants
PCT/FR1997/000106 WO1997025998A1 (fr)	1996-01-18	1997-01-20	Substances extraites de dictyotales, leur procede d'obtention et les compositions en renfermant

Publications (2)

Publication Number	Publication Date
AP9701085A0 AP9701085A0 (en)	1997-10-31
AP732A true AP732A (en)	1999-02-10

Family

ID=9488210

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/1997/001085A AP732A (en)	1996-01-18	1997-01-20	Substances extracted from dictyotales, preparation method therefor, and compositions containing same.

Country Status (20)

Country	Link
US (1)	US5961981A (de)
EP (1)	EP0817641B1 (de)
JP (1)	JPH11502235A (de)
KR (1)	KR19980703075A (de)
CN (1)	CN100536858C (de)
AP (1)	AP732A (de)
AT (1)	ATE241996T1 (de)
AU (1)	AU724083B2 (de)
BR (1)	BR9704626A (de)
CA (1)	CA2216600A1 (de)
DE (1)	DE69722514T2 (de)
DK (1)	DK0817641T3 (de)
ES (1)	ES2219748T3 (de)
FR (1)	FR2743723B1 (de)
HU (1)	HUP9900952A3 (de)
NZ (1)	NZ326391A (de)
OA (1)	OA10508A (de)
PL (1)	PL322310A1 (de)
RU (1)	RU2195955C2 (de)
WO (1)	WO1997025998A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2760192B1 (fr) *	1997-03-03	1999-05-21	Inovat Sarl	Procede d'obtention de nouvelles substances biologiquement actives, les substances ainsi obtenues et les compositions en refermant
GB9709082D0 (en)	1997-05-06	1997-06-25	Ciba Geigy Ag	Organic compositions
FR2803523B1 (fr) *	2000-01-10	2006-09-01	Texinfine Sa	Nouvelles compositions a base d'extraits de dictyotales et leur utilisation
FR2811563B1 (fr) *	2000-07-13	2003-06-20	Oreal	Composition, notamment cosmetique, comprenant la dhea et/ou un precurseur ou derive, et au moins un compose augmentant la synthese des glycosaminoglycanes
KR100386416B1 (ko) *	2000-08-31	2003-06-02	주식회사 내비켐	해조류의 수용성 대사산물을 이용한 환경 친화적인방오제
KR100419134B1 (ko) *	2000-10-16	2004-02-14	엔프라니 주식회사	파디나파보니카 추출물을 함유한 피부 보호용 화장료 조성물
FR2827303B1 (fr) *	2001-07-13	2004-09-10	Texinfine Sa	Procede d'obtention d'une preparation titree d'algues et les preparations titrees en resultant
US7354956B2 (en) *	2002-04-12	2008-04-08	L'oreal	Composition containing a sapogenin and use thereof
TW200505470A (en) *	2002-12-05	2005-02-16	Takara Bio Inc	Therapeutic agent
WO2007032962A2 (en) *	2005-09-09	2007-03-22	University Of Kentucky	Compositions and methods for intranasal delivery of tricyclic cannabinoids
FR2896692A1 (fr) *	2006-01-30	2007-08-03	Jean Alexis Grimaud	Nouvelles compositions cosmetologiques et dermatologiques a base d'extraits d'algues
GB0921001D0 (en)	2009-11-30	2010-01-13	Aqua Bio Technology Asa	Products and uses
FR3106061B1 (fr)	2020-01-10	2022-10-21	Gelyma	Composition cosmétique comprenant des extraits de Padina Pavonica pour améliorer la formation et la maturation du stratum corneum
FR3106057B1 (fr)	2020-01-10	2022-02-04	Gelyma	Composition cosmétique comprenant des extraits de Padina Pavonica pour améliorer cicatrisation de la peau

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0655250A1 (de) *	1993-11-22	1995-05-31	Texinfine	Zubereitungen auf Basis von Padina Algen oder ihrer Extrakten, und ihre pharmazeutische, Nährungsmittel oder für die Kultur von Mollusken oder Arthropoden Kulturverwendungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2648463B1 (fr) *	1989-06-14	1993-01-22	Inst Fs Rech Expl Mer	Polysaccharides sulfates, agent anticoagulant et agent anticomplementaire obtenus a partir de fucanes d'algues brunes et leur procede d'obtention
IT1249447B (it) *	1991-08-28	1995-02-23	Arrigo Claudio D	Farmaco antineoplastico di estrazione vegetale. procedimento per la sua preparazione.

1996
- 1996-01-18 FR FR9600522A patent/FR2743723B1/fr not_active Expired - Fee Related
1997
- 1997-01-20 EP EP97901124A patent/EP0817641B1/de not_active Expired - Lifetime
- 1997-01-20 ES ES97901124T patent/ES2219748T3/es not_active Expired - Lifetime
- 1997-01-20 CA CA002216600A patent/CA2216600A1/fr not_active Abandoned
- 1997-01-20 CN CNB971902186A patent/CN100536858C/zh not_active Expired - Fee Related
- 1997-01-20 BR BR9704626-4A patent/BR9704626A/pt not_active Application Discontinuation
- 1997-01-20 WO PCT/FR1997/000106 patent/WO1997025998A1/fr not_active Ceased
- 1997-01-20 HU HU9900952A patent/HUP9900952A3/hu unknown
- 1997-01-20 JP JP9525757A patent/JPH11502235A/ja not_active Ceased
- 1997-01-20 KR KR1019970706484A patent/KR19980703075A/ko not_active Abandoned
- 1997-01-20 AP APAP/P/1997/001085A patent/AP732A/en active
- 1997-01-20 NZ NZ326391A patent/NZ326391A/en unknown
- 1997-01-20 DK DK97901124T patent/DK0817641T3/da active
- 1997-01-20 RU RU97117177/14A patent/RU2195955C2/ru active
- 1997-01-20 US US08/930,365 patent/US5961981A/en not_active Expired - Fee Related
- 1997-01-20 PL PL97322310A patent/PL322310A1/xx unknown
- 1997-01-20 AU AU14480/97A patent/AU724083B2/en not_active Ceased
- 1997-01-20 DE DE69722514T patent/DE69722514T2/de not_active Expired - Fee Related
- 1997-01-20 AT AT97901124T patent/ATE241996T1/de not_active IP Right Cessation
- 1997-09-18 OA OA70079A patent/OA10508A/fr unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0655250A1 (de) *	1993-11-22	1995-05-31	Texinfine	Zubereitungen auf Basis von Padina Algen oder ihrer Extrakten, und ihre pharmazeutische, Nährungsmittel oder für die Kultur von Mollusken oder Arthropoden Kulturverwendungen

Also Published As

Publication number	Publication date
HUP9900952A2 (hu)	1999-07-28
FR2743723A1 (fr)	1997-07-25
WO1997025998A1 (fr)	1997-07-24
OA10508A (fr)	2002-04-24
HUP9900952A3 (en)	2000-11-28
KR19980703075A (ko)	1998-09-05
DE69722514D1 (de)	2003-07-10
CN100536858C (zh)	2009-09-09
DK0817641T3 (da)	2003-09-29
FR2743723B1 (fr)	1998-04-17
RU2195955C2 (ru)	2003-01-10
CA2216600A1 (fr)	1997-07-24
NZ326391A (en)	2001-06-29
ES2219748T3 (es)	2004-12-01
BR9704626A (pt)	1999-12-28
EP0817641A1 (de)	1998-01-14
AU724083B2 (en)	2000-09-14
ATE241996T1 (de)	2003-06-15
PL322310A1 (en)	1998-01-19
US5961981A (en)	1999-10-05
DE69722514T2 (de)	2004-04-29
EP0817641B1 (de)	2003-06-04
AP9701085A0 (en)	1997-10-31
CN1183045A (zh)	1998-05-27
AU1448097A (en)	1997-08-11
JPH11502235A (ja)	1999-02-23

Publication	Publication Date	Title
AP732A (en)	1999-02-10	Substances extracted from dictyotales, preparation method therefor, and compositions containing same.
JP5047433B2 (ja)	2012-10-10	真珠層の総ての成分を含んでなる、真珠層の抽出による組成物の製造方法、この方法を用いて得られる組成物、およびこの組成物の化粧品および皮膚科学における使用
KR101219520B1 (ko)	2013-01-08	항염증, 항산화 또는 항세균 조성물
DE69819006T2 (de)	2004-06-24	Verwendung von ginsenoside rb1 zur stimulierung der elastinsynthese
CN106456478A (zh)	2017-02-22	没食子酸及其衍生物的化妆品和医药应用
EA013502B1 (ru)	2010-06-30	Композиция на основе растительных экстрактов ajuga reptans для предупреждения или лечения андрогенной алопеции, телогенного выпадения волос и акне
KR102298530B1 (ko)	2021-09-07	아쿠아포닉스 재배기술을 이용한 병풀 추출물을 포함하는 화장료 조성물
KR20160091300A (ko)	2016-08-02	피부 노화 징후의 출현을 방지 또는 지연시키기 위한 활성제로서의 브라소카틀레야 마르셀라 코스 난초 추출물의 용도
KR102523606B1 (ko)	2023-04-19	알팔파 씨앗에서 추출된 다당체를 유효성분으로 함유하는 화장료 조성물
JP2021187787A (ja)	2021-12-13	エクソソーム分泌促進剤、エクソソーム取り込み促進剤、エクソソーム分泌促進用美容組成物、及びエクソソーム分泌促進方法
US20070116789A1 (en)	2007-05-24	Extracts of durian fruit for use in skin care compositions
CN114262360B (zh)	2023-09-01	一种带鱼抗氧化肽及其抗氧化面霜
KR20180001652A (ko)	2018-01-05	밀몽화 추출물 또는 이의 분획물을 유효성분으로 함유하는 피부장벽강화용 화장료 조성물
KR101798632B1 (ko)	2017-11-16	피뿌리풀 추출물 또는 그의 분획물을 포함하는 화장 조성물 및 그의 용도
KR101618726B1 (ko)	2016-05-09	명태껍질로부터 엘라스틴을 포함하는 단백질추출물을 제조하는 방법
KR20110048378A (ko)	2011-05-11	함초 캘러스 추출물과 채널드랙 추출물을 함유하는 피부주름개선 또는 탄력증진용 화장료 조성물
KR101609217B1 (ko)	2016-04-05	해파리로부터 당단백질을 제조하는 방법 및 그 당단백질을 함유하는 화장료 조성물
KR102627688B1 (ko)	2024-01-23	죽단화 꽃 에센셜오일을 유효성분으로 포함하는 피부 재생 및 주름 개선용 화장료 조성물
KR102908981B1 (ko)	2026-01-15	예덕나무 추출물과 펩타이드 복합물을 함유하는 주름 개선 화장료 조성물
FR2767690A1 (fr)	1999-03-05	Utilisations d'extraits de la plante rhoeo discolor dans le domaine de la cosmetique et de la pharmacie, notamment de la dermatologie
HK1016468A (en)	1999-11-05	Substances extracted from dictyotales, preparation method therefor, and compositions containing the same
KR20200004230A (ko)	2020-01-13	화장료 조성물 및 이의 제조방법
KR102298531B1 (ko)	2021-09-07	아쿠아포닉스 재배기술을 이용한 삼백초 추출물을 포함하는 화장료 조성물
KR20160003913A (ko)	2016-01-12	한약재 추출물을 포함하는 피부 탄력 증진 또는 주름 개선용 화장료 조성물
KR20160077701A (ko)	2016-07-04	층꽃나무 추출물을 함유하는 항산화, 미백 및 주름 개선을 위한 조성물