AP9700940A0 - Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring - Google Patents

Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring

Info

Publication number: AP9700940A0
Authority: AP; ARIPO
Prior art keywords: carbocyclic ring; base attached; nucleoside analogues; substituted benzimidazole; antiviral nucleoside
Prior art date: 1994-09-09

Application number

AP9700940A

Other versions

AP741A (en

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-09

Filing date

1995-09-11

Publication date

1997-04-30

1994-09-09 Priority claimed from US08/304,006 external-priority patent/US5534535A/en

1995-09-11 Application filed by Wellcome Found filed Critical Wellcome Found

1997-04-30 Publication of AP9700940A0 publication Critical patent/AP9700940A0/en

1999-04-26 Application granted granted Critical

1999-04-26 Publication of AP741A publication Critical patent/AP741A/en

Links

230000000840 anti-viral effect Effects 0.000 title 1
125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
125000002837 carbocyclic group Chemical group 0.000 title 1
229940127073 nucleoside analogue Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

APAP/P/1997/000940A 1994-09-09 1995-09-11 Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring. AP741A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/304,006 US5534535A (en)	1992-03-09	1994-09-09	Therapeutic nucleosides
PCT/US1995/011366 WO1996007646A1 (en)	1994-09-09	1995-09-11	Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring

Publications (2)

Publication Number	Publication Date
AP9700940A0 true AP9700940A0 (en)	1997-04-30
AP741A AP741A (en)	1999-04-26

Family

ID=23174626

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/1997/000940A AP741A (en)	1994-09-09	1995-09-11	Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring.

Country Status (17)

Country	Link
EP (1)	EP0779885A1 (en)
JP (1)	JPH10505092A (en)
CN (1)	CN1164855A (en)
AP (1)	AP741A (en)
AU (1)	AU3692895A (en)
BR (1)	BR9508826A (en)
CA (1)	CA2199502A1 (en)
CZ (1)	CZ71297A3 (en)
FI (1)	FI970959A7 (en)
HU (1)	HUT77440A (en)
IS (1)	IS4436A (en)
NO (1)	NO971070L (en)
NZ (1)	NZ294095A (en)
OA (1)	OA10601A (en)
PL (1)	PL319440A1 (en)
SK (1)	SK29197A3 (en)
WO (1)	WO1996007646A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5912356A (en) *	1995-09-11	1999-06-15	Glaxo Wellcome Inc.	Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring
GB9600142D0 (en) *	1996-01-05	1996-03-06	Wellcome Found	Chemical compounds
US6413938B1 (en)	1997-02-13	2002-07-02	The Regents Of The University Of Michigan	Benzimidazole derivatives for the treatment of viral infections
AU744176B2 (en)	1997-07-30	2002-02-14	Glaxo Group Limited	Lyxofuranosyl benzimidazoles as antiviral agents
US6770666B2 (en)	1999-12-27	2004-08-03	Japan Tobacco Inc.	Fused-ring compounds and use thereof as drugs
CZ20013424A3 (en)	1999-12-27	2002-02-13	Japan Tobacco Inc.	Compounds with fused rings and their use as medicaments
GB0008939D0 (en)	2000-04-11	2000-05-31	Glaxo Group Ltd	Process for preparing substituted benzimidazole compounds
AR035543A1 (en) *	2001-06-26	2004-06-16	Japan Tobacco Inc	THERAPEUTIC AGENT FOR HEPATITIS C THAT INCLUDES A CONDENSED RING COMPOUND, CONDENSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS, BENZIMIDAZOL, THIAZOL AND BIFENYL COMPOUNDS USED AS INTERMEDIARY COMPARTMENTS OF COMPARTMENTS
CN1834090B (en) *	2005-03-18	2011-06-29	中国科学院上海药物研究所	Benzimidazole compounds, its preparation and uses
EP2540727B1 (en)	2007-08-02	2018-07-25	Millennium Pharmaceuticals, Inc.	Sulfamoylating reagent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9205071D0 (en) *	1992-03-09	1992-04-22	Wellcome Found	Therapeutic nucleosides

1995
- 1995-09-11 JP JP8509679A patent/JPH10505092A/en not_active Ceased
- 1995-09-11 HU HU9702310A patent/HUT77440A/en unknown
- 1995-09-11 AU AU36928/95A patent/AU3692895A/en not_active Abandoned
- 1995-09-11 SK SK291-97A patent/SK29197A3/en unknown
- 1995-09-11 AP APAP/P/1997/000940A patent/AP741A/en active
- 1995-09-11 CZ CZ97712A patent/CZ71297A3/en unknown
- 1995-09-11 WO PCT/US1995/011366 patent/WO1996007646A1/en not_active Ceased
- 1995-09-11 CN CN95196148A patent/CN1164855A/en active Pending
- 1995-09-11 PL PL95319440A patent/PL319440A1/en unknown
- 1995-09-11 EP EP95934402A patent/EP0779885A1/en not_active Withdrawn
- 1995-09-11 NZ NZ294095A patent/NZ294095A/en unknown
- 1995-09-11 CA CA002199502A patent/CA2199502A1/en not_active Abandoned
- 1995-09-11 BR BR9508826A patent/BR9508826A/en not_active Application Discontinuation
1997
- 1997-03-06 FI FI970959A patent/FI970959A7/en unknown
- 1997-03-07 OA OA60973A patent/OA10601A/en unknown
- 1997-03-07 IS IS4436A patent/IS4436A/en unknown
- 1997-03-07 NO NO971070A patent/NO971070L/en unknown

Also Published As

Publication number	Publication date
JPH10505092A (en)	1998-05-19
SK29197A3 (en)	1997-10-08
PL319440A1 (en)	1997-08-04
MX9701789A (en)	1997-10-31
CZ71297A3 (en)	1997-08-13
AU3692895A (en)	1996-03-27
CN1164855A (en)	1997-11-12
EP0779885A1 (en)	1997-06-25
FI970959A0 (en)	1997-03-06
NO971070L (en)	1997-05-07
WO1996007646A1 (en)	1996-03-14
IS4436A (en)	1997-03-07
HUT77440A (en)	1998-04-28
CA2199502A1 (en)	1996-03-14
FI970959A7 (en)	1997-05-06
BR9508826A (en)	1997-09-30
NZ294095A (en)	1998-08-26
OA10601A (en)	2002-09-03
NO971070D0 (en)	1997-03-07
AP741A (en)	1999-04-26

Publication	Publication Date	Title
FI935114A7 (en)	1993-12-30	Backbone-modified oligonucleotide analogs
CY1508A (en)	1990-08-03	Antiviral nucleosides
IL113432A0 (en)	1995-07-31	Diastereoselective synthesis of nucleoside analogues
FI902386A7 (en)	1990-11-16	Nucleoside analogues
FI944134L (en)	1994-11-07	Antiviral nucleoside analogues
ZA915657B (en)	1992-05-27	Novel carbocyclic analogs of certain nucleosides
IL99466A0 (en)	1992-08-18	Noel carbocyclic adenosine analogs useful as immunosuppressants
ZA898834B (en)	1990-08-29	Antiviral agents
AU3692895A (en)	1996-03-27	Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring
ZA876673B (en)	1989-04-26	Nucleoside analogues
IL143867A0 (en)	2002-04-21	Antiviral nucleoside analogues
GB8827337D0 (en)	1988-12-29	Nucleoside analogues
FI950535L (en)	1995-02-07	Stereoselective synthesis of nucleoside analogs using a bicyclic intermediate
EP0450065A4 (en)	1992-01-02	Antiviral agent
GB2184944B (en)	1989-12-28	Antiviral agents
ZA861933B (en)	1987-10-28	Antiviral nucleosides
EP0243192A3 (en)	1990-06-27	Antiviral 8-phenylxanthines
AU4378589A (en)	1990-05-03	Carbocyclic nucleoside analogs
GB9111967D0 (en)	1991-07-24	2,5'-nucleotide analogs as antiviral agents
GB8608272D0 (en)	1986-05-08	Antiviral combination
IE893412L (en)	1990-04-25	Carbocyclic nucleoside analogues
ZA917151B (en)	1992-05-27	Carbocyclic nucleoside analogs useful as immunosuppressants
CY2006A (en)	1997-12-05	Antiviral combinations containing nucleoside analogs
ZA917152B (en)	1992-05-27	Novel carbocyclic adenosine analogs useful as immunosuppressants
GB9222203D0 (en)	1992-12-02	Nucleoside analogues