IS4436A - Antiviral nucleoside analogues containing substituted benzimidazole bases linked to a carbon ring - Google Patents

Antiviral nucleoside analogues containing substituted benzimidazole bases linked to a carbon ring

Info

Publication number
IS4436A
IS4436A IS4436A IS4436A IS4436A IS 4436 A IS4436 A IS 4436A IS 4436 A IS4436 A IS 4436A IS 4436 A IS4436 A IS 4436A IS 4436 A IS4436 A IS 4436A
Authority
IS
Iceland
Prior art keywords
carbon ring
nucleoside analogues
containing substituted
substituted benzimidazole
antiviral nucleoside
Prior art date
Application number
IS4436A
Other languages
Icelandic (is)
Inventor
B. Townsend Leroy
Mary Daluge Susan
Original Assignee
The Wellcome Foundation Limited
The Regents Of The University Of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/304,006 external-priority patent/US5534535A/en
Application filed by The Wellcome Foundation Limited, The Regents Of The University Of Michigan filed Critical The Wellcome Foundation Limited
Publication of IS4436A publication Critical patent/IS4436A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS4436A 1994-09-09 1997-03-07 Antiviral nucleoside analogues containing substituted benzimidazole bases linked to a carbon ring IS4436A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/304,006 US5534535A (en) 1992-03-09 1994-09-09 Therapeutic nucleosides
PCT/US1995/011366 WO1996007646A1 (en) 1994-09-09 1995-09-11 Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring

Publications (1)

Publication Number Publication Date
IS4436A true IS4436A (en) 1997-03-07

Family

ID=23174626

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4436A IS4436A (en) 1994-09-09 1997-03-07 Antiviral nucleoside analogues containing substituted benzimidazole bases linked to a carbon ring

Country Status (17)

Country Link
EP (1) EP0779885A1 (en)
JP (1) JPH10505092A (en)
CN (1) CN1164855A (en)
AP (1) AP741A (en)
AU (1) AU3692895A (en)
BR (1) BR9508826A (en)
CA (1) CA2199502A1 (en)
CZ (1) CZ71297A3 (en)
FI (1) FI970959A7 (en)
HU (1) HUT77440A (en)
IS (1) IS4436A (en)
NO (1) NO971070L (en)
NZ (1) NZ294095A (en)
OA (1) OA10601A (en)
PL (1) PL319440A1 (en)
SK (1) SK29197A3 (en)
WO (1) WO1996007646A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912356A (en) * 1995-09-11 1999-06-15 Glaxo Wellcome Inc. Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
AU6221998A (en) 1997-02-13 1998-09-08 Glaxo Group Limited Benzimidazole derivatives
CN1272113A (en) 1997-07-30 2000-11-01 密歇根大学董事会 Lyxofuranosyl benzimidazoles as antiviral agents
US6770666B2 (en) 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
CA2363274A1 (en) 1999-12-27 2001-07-05 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs for hepatitis c
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
AR035543A1 (en) * 2001-06-26 2004-06-16 Japan Tobacco Inc THERAPEUTIC AGENT FOR HEPATITIS C THAT INCLUDES A CONDENSED RING COMPOUND, CONDENSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS, BENZIMIDAZOL, THIAZOL AND BIFENYL COMPOUNDS USED AS INTERMEDIARY COMPARTMENTS OF COMPARTMENTS
CN1834090B (en) * 2005-03-18 2011-06-29 中国科学院上海药物研究所 Benzimidazole compound, its preparation method and use
KR101925902B1 (en) 2007-08-02 2018-12-06 밀레니엄 파머슈티컬스 인코퍼레이티드 Process for the synthesis of e1 activating enzyme inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides

Also Published As

Publication number Publication date
MX9701789A (en) 1997-10-31
JPH10505092A (en) 1998-05-19
AU3692895A (en) 1996-03-27
FI970959A7 (en) 1997-05-06
AP9700940A0 (en) 1997-04-30
SK29197A3 (en) 1997-10-08
EP0779885A1 (en) 1997-06-25
BR9508826A (en) 1997-09-30
CN1164855A (en) 1997-11-12
CA2199502A1 (en) 1996-03-14
OA10601A (en) 2002-09-03
HUT77440A (en) 1998-04-28
NO971070D0 (en) 1997-03-07
CZ71297A3 (en) 1997-08-13
PL319440A1 (en) 1997-08-04
AP741A (en) 1999-04-26
NO971070L (en) 1997-05-07
NZ294095A (en) 1998-08-26
FI970959A0 (en) 1997-03-06
WO1996007646A1 (en) 1996-03-14

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