AP9801253A0 - 9-Oxime erythromycin derivatives. - Google Patents

9-Oxime erythromycin derivatives.

Info

Publication number
AP9801253A0
AP9801253A0 APAP/P/1998/001253A AP9801253A AP9801253A0 AP 9801253 A0 AP9801253 A0 AP 9801253A0 AP 9801253 A AP9801253 A AP 9801253A AP 9801253 A0 AP9801253 A0 AP 9801253A0
Authority
AP
ARIPO
Prior art keywords
compounds
formula
erythromycin derivatives
oxime erythromycin
methods
Prior art date
Application number
APAP/P/1998/001253A
Other languages
English (en)
Inventor
Yong-Jin Wu
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AP9801253A0 publication Critical patent/AP9801253A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
APAP/P/1998/001253A 1997-06-11 1998-06-04 9-Oxime erythromycin derivatives. AP9801253A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4934997P 1997-06-11 1997-06-11

Publications (1)

Publication Number Publication Date
AP9801253A0 true AP9801253A0 (en) 1999-12-04

Family

ID=21959341

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001253A AP9801253A0 (en) 1997-06-11 1998-06-04 9-Oxime erythromycin derivatives.

Country Status (31)

Country Link
EP (1) EP0988308A1 (id)
JP (1) JP2000513026A (id)
KR (1) KR20010013660A (id)
CN (1) CN1259135A (id)
AP (1) AP9801253A0 (id)
AR (1) AR012244A1 (id)
AU (1) AU7226798A (id)
BG (1) BG103947A (id)
BR (1) BR9810021A (id)
CA (1) CA2293335A1 (id)
CO (1) CO4940506A1 (id)
CZ (1) CZ9904388A3 (id)
EA (1) EA199901016A1 (id)
GT (1) GT199800074A (id)
HN (1) HN1998000073A (id)
HR (1) HRP980316A2 (id)
HU (1) HUP0002252A3 (id)
ID (1) ID24529A (id)
IL (1) IL132767A0 (id)
IS (1) IS5251A (id)
MA (1) MA26505A1 (id)
NO (1) NO996108L (id)
OA (1) OA11225A (id)
PA (1) PA8451801A1 (id)
PE (1) PE79899A1 (id)
PL (1) PL337606A1 (id)
TN (1) TNSN98083A1 (id)
TR (1) TR199902995T2 (id)
TW (1) TW448174B (id)
WO (1) WO1998056800A1 (id)
ZA (1) ZA985018B (id)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
AU5299499A (en) 1998-09-22 2000-04-10 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en) 1998-12-02 2001-07-10 Pfizer Inc. Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) * 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
US6395710B1 (en) * 1999-04-16 2002-05-28 Kosan Biosciences, Inc. Macrolide antiinfective agents
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
ATE250076T1 (de) * 1999-06-07 2003-10-15 Abbott Lab 6-o-carbamat ketolide derivate
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1439186A3 (en) * 1999-12-29 2004-11-03 Pfizer Products Inc. Intermediates for novel antibacterial and prokinetic macrolides
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en) 2000-07-05 2002-06-11 Pfizer Inc. Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
EP1638549A4 (en) * 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
CA2703475A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
CN102146085B (zh) * 2010-02-09 2014-03-26 北京理工大学 一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
WO2011146829A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
KR20010013660A (ko) 2001-02-26
HUP0002252A3 (en) 2002-01-28
GT199800074A (es) 1999-11-27
WO1998056800A1 (en) 1998-12-17
NO996108D0 (no) 1999-12-10
HUP0002252A2 (hu) 2000-12-28
EA199901016A1 (ru) 2000-06-26
BG103947A (en) 2000-07-31
TR199902995T2 (xx) 2000-02-21
HRP980316A2 (en) 1999-04-30
HN1998000073A (es) 1999-01-08
ZA985018B (en) 1999-12-10
CZ9904388A3 (cs) 2002-10-16
EP0988308A1 (en) 2000-03-29
AR012244A1 (es) 2000-09-27
PE79899A1 (es) 1999-08-25
PL337606A1 (en) 2000-08-28
IS5251A (is) 1999-11-16
IL132767A0 (en) 2001-03-19
BR9810021A (pt) 2000-09-19
AU7226798A (en) 1998-12-30
JP2000513026A (ja) 2000-10-03
PA8451801A1 (es) 2000-05-24
TW448174B (en) 2001-08-01
MA26505A1 (fr) 2004-12-20
CN1259135A (zh) 2000-07-05
OA11225A (en) 2003-07-17
ID24529A (id) 2000-07-20
TNSN98083A1 (fr) 2005-03-15
NO996108L (no) 2000-02-10
CO4940506A1 (es) 2000-07-24
CA2293335A1 (en) 1998-12-17

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