AR005472A1 - Inhibidores de la formacion cd23 humana soluble, un procedimiento para su preparacion, el uso de los mismos para la manufactura de un medicamento,composicion farmaceutica y compuestos intermediarios - Google Patents
Inhibidores de la formacion cd23 humana soluble, un procedimiento para su preparacion, el uso de los mismos para la manufactura de un medicamento,composicion farmaceutica y compuestos intermediariosInfo
- Publication number
- AR005472A1 AR005472A1 ARP970100153A ARP970100153A AR005472A1 AR 005472 A1 AR005472 A1 AR 005472A1 AR P970100153 A ARP970100153 A AR P970100153A AR P970100153 A ARP970100153 A AR P970100153A AR 005472 A1 AR005472 A1 AR 005472A1
- Authority
- AR
- Argentina
- Prior art keywords
- inhibitors
- manufacture
- preparation
- pharmaceutical composition
- training
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 101000878605 Homo sapiens Low affinity immunoglobulin epsilon Fc receptor Proteins 0.000 title abstract 2
- 102100038007 Low affinity immunoglobulin epsilon Fc receptor Human genes 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000012261 overproduction Methods 0.000 abstract 1
- 239000012450 pharmaceutical intermediate Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Los compuestos de fórmula (1) en la cual R y R3 son cado uno independientemente hidrógeno, alquilo, alquenilo, alquinilo o arilo; R1 esarilmetilo; y R2 es alquilo, alquenilo, arilo, cicloalquilo o cicloalquenilo, y sus derivados farmacéuticamente aceptables, son útiles en el tratamiento y laprofilaxis de trastornos en los cuales está implicada la superproducción de sCD23. Inhibidores de la formación CD23 humana soluble, un procedimiento parasu preparación, el uso de los mismospara la manufactura de un mediamento, composición farmacéutica y compuestos intermediarios.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9601041.8A GB9601041D0 (en) | 1996-01-17 | 1996-01-17 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR005472A1 true AR005472A1 (es) | 1999-06-23 |
Family
ID=10787226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970100153A AR005472A1 (es) | 1996-01-17 | 1997-01-15 | Inhibidores de la formacion cd23 humana soluble, un procedimiento para su preparacion, el uso de los mismos para la manufactura de un medicamento,composicion farmaceutica y compuestos intermediarios |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0912545A1 (es) |
| JP (1) | JP2000503312A (es) |
| KR (1) | KR19990077325A (es) |
| CN (1) | CN1213368A (es) |
| AR (1) | AR005472A1 (es) |
| AU (1) | AU725056B2 (es) |
| BR (1) | BR9707024A (es) |
| CA (1) | CA2242913A1 (es) |
| CZ (1) | CZ222498A3 (es) |
| GB (1) | GB9601041D0 (es) |
| HU (1) | HUP9901022A3 (es) |
| IL (1) | IL125381A0 (es) |
| NO (1) | NO983283L (es) |
| NZ (1) | NZ326352A (es) |
| PL (1) | PL327820A1 (es) |
| TR (1) | TR199801380T2 (es) |
| TW (1) | TW462967B (es) |
| WO (1) | WO1997026257A1 (es) |
| ZA (1) | ZA97345B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548084B2 (en) | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
| GB9609795D0 (en) * | 1996-05-10 | 1996-07-17 | Smithkline Beecham Plc | Novel compounds |
| AU1960100A (en) * | 1999-01-06 | 2000-07-24 | Mcmaster University | Method of preventing immune and hypersensitivity reactions |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| AU2001271068A1 (en) * | 2000-07-18 | 2002-01-30 | Chugai Seiyaku Kabushiki Kaisha | Matrix metalloprotease inhibitors |
| WO2003064472A2 (en) * | 2002-01-28 | 2003-08-07 | Aimsco Limited | Treatment of ms with goat serum |
| EP1787986A4 (en) | 2004-08-10 | 2007-08-22 | Shizuoka Coffein Co Ltd | HYDROXAMINE ACID DERIVATIVE AND MEDICAMENT THEREFORE AS AN ACTIVE COMPONENT |
| KR100844277B1 (ko) * | 2005-04-29 | 2008-07-07 | (주)아모레퍼시픽 | 히드록삼산 유도체 및 이의 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743587A (en) * | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| GB9504084D0 (en) * | 1995-03-01 | 1995-04-19 | British Biotech Pharm | Synthesis of carboxylic and hydroxamic acid derivatives |
-
1996
- 1996-01-17 GB GBGB9601041.8A patent/GB9601041D0/en active Pending
-
1997
- 1997-01-14 TR TR1998/01380T patent/TR199801380T2/xx unknown
- 1997-01-14 HU HU9901022A patent/HUP9901022A3/hu unknown
- 1997-01-14 AU AU14436/97A patent/AU725056B2/en not_active Ceased
- 1997-01-14 EP EP97901055A patent/EP0912545A1/en not_active Withdrawn
- 1997-01-14 IL IL12538197A patent/IL125381A0/xx unknown
- 1997-01-14 NZ NZ326352A patent/NZ326352A/xx unknown
- 1997-01-14 JP JP9525693A patent/JP2000503312A/ja active Pending
- 1997-01-14 CZ CZ982224A patent/CZ222498A3/cs unknown
- 1997-01-14 CA CA002242913A patent/CA2242913A1/en not_active Abandoned
- 1997-01-14 BR BR9707024A patent/BR9707024A/pt unknown
- 1997-01-14 KR KR1019980705472A patent/KR19990077325A/ko not_active Withdrawn
- 1997-01-14 PL PL97327820A patent/PL327820A1/xx unknown
- 1997-01-14 WO PCT/EP1997/000196 patent/WO1997026257A1/en not_active Ceased
- 1997-01-14 CN CN97192982A patent/CN1213368A/zh active Pending
- 1997-01-15 AR ARP970100153A patent/AR005472A1/es unknown
- 1997-01-16 ZA ZA97345A patent/ZA97345B/xx unknown
- 1997-01-30 TW TW086101017A patent/TW462967B/zh active
-
1998
- 1998-07-16 NO NO983283A patent/NO983283L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL125381A0 (en) | 1999-03-12 |
| HUP9901022A2 (hu) | 1999-07-28 |
| KR19990077325A (ko) | 1999-10-25 |
| NZ326352A (en) | 2000-03-27 |
| HUP9901022A3 (en) | 2001-11-28 |
| AU725056B2 (en) | 2000-10-05 |
| WO1997026257A1 (en) | 1997-07-24 |
| NO983283L (no) | 1998-09-16 |
| ZA97345B (en) | 1998-07-16 |
| BR9707024A (pt) | 1999-07-20 |
| NO983283D0 (no) | 1998-07-16 |
| TW462967B (en) | 2001-11-11 |
| TR199801380T2 (xx) | 1998-10-21 |
| CA2242913A1 (en) | 1997-07-24 |
| AU1443697A (en) | 1997-08-11 |
| JP2000503312A (ja) | 2000-03-21 |
| EP0912545A1 (en) | 1999-05-06 |
| GB9601041D0 (en) | 1996-03-20 |
| PL327820A1 (en) | 1999-01-04 |
| CZ222498A3 (cs) | 1999-03-17 |
| CN1213368A (zh) | 1999-04-07 |
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