AR010068A1 - Tetrahidro-1,3,5-triazin-2[1h]-tionas sustituidas como agentes antiateroescleroticos y composicion farmaceutica que los contiene - Google Patents
Tetrahidro-1,3,5-triazin-2[1h]-tionas sustituidas como agentes antiateroescleroticos y composicion farmaceutica que los contieneInfo
- Publication number
- AR010068A1 AR010068A1 ARP970105309A ARP970105309A AR010068A1 AR 010068 A1 AR010068 A1 AR 010068A1 AR P970105309 A ARP970105309 A AR P970105309A AR P970105309 A ARP970105309 A AR P970105309A AR 010068 A1 AR010068 A1 AR 010068A1
- Authority
- AR
- Argentina
- Prior art keywords
- carbon atoms
- triazin
- tetrahydro
- substituted
- pharmaceutical composition
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 15
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- -1 -SCF3 Chemical group 0.000 abstract 1
- 241001061127 Thione Species 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000004428 fluoroalkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/08—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74887696A | 1996-11-14 | 1996-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010068A1 true AR010068A1 (es) | 2000-05-17 |
Family
ID=25011313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105309A AR010068A1 (es) | 1996-11-14 | 1997-11-13 | Tetrahidro-1,3,5-triazin-2[1h]-tionas sustituidas como agentes antiateroescleroticos y composicion farmaceutica que los contiene |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0938480A1 (de) |
| JP (1) | JP2001503769A (de) |
| AR (1) | AR010068A1 (de) |
| AU (1) | AU5170698A (de) |
| CA (1) | CA2271728A1 (de) |
| WO (1) | WO1998021190A1 (de) |
| ZA (1) | ZA9710265B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001294910A1 (en) * | 2000-10-02 | 2002-04-15 | American Home Products Corporation | 3-thioxo-(1,2,4)-oxadiazinan-5-one and their use as anti-antherosclerotic agents |
| MXPA04000565A (es) * | 2001-07-19 | 2005-06-17 | Cv Therapeutics Inc | Compuestos de piperazina sustituidos y su uso como inhibidores de oxidacion de acidos grasos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK236878A (da) * | 1977-07-22 | 1979-01-23 | Pfizer | Tetrahydro-s-triazin-2(1h)-thioner |
| HUT62558A (en) * | 1991-07-01 | 1993-05-28 | Sandoz Ag | Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same |
| US5554607A (en) * | 1995-11-28 | 1996-09-10 | American Home Products Corporation | Use of 2-thioxo-imidazolin-4-one derivatives in the treatment of atherosclerosis |
| NZ332199A (en) * | 1996-03-07 | 1999-03-29 | American Home Prod | 2-thioxotetrahydropyrimidin-4-one derivatives |
-
1997
- 1997-11-10 EP EP97946555A patent/EP0938480A1/de not_active Withdrawn
- 1997-11-10 CA CA002271728A patent/CA2271728A1/en not_active Abandoned
- 1997-11-10 WO PCT/US1997/020233 patent/WO1998021190A1/en not_active Ceased
- 1997-11-10 AU AU51706/98A patent/AU5170698A/en not_active Abandoned
- 1997-11-10 JP JP52266598A patent/JP2001503769A/ja active Pending
- 1997-11-13 AR ARP970105309A patent/AR010068A1/es unknown
- 1997-11-13 ZA ZA9710265A patent/ZA9710265B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA9710265B (en) | 1999-08-13 |
| EP0938480A1 (de) | 1999-09-01 |
| CA2271728A1 (en) | 1998-05-22 |
| JP2001503769A (ja) | 2001-03-21 |
| AU5170698A (en) | 1998-06-03 |
| WO1998021190A1 (en) | 1998-05-22 |
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