AR028676A1 - PROCEDIMIENTO PARA LA DETECCION DE ANTICUERPOS ANTITRANSGLUTAMINASA CON UTILIDAD EN EL DIAGNoSTICO DE LA ENFERMEDAD CELíACA - Google Patents

PROCEDIMIENTO PARA LA DETECCION DE ANTICUERPOS ANTITRANSGLUTAMINASA CON UTILIDAD EN EL DIAGNoSTICO DE LA ENFERMEDAD CELíACA

Info

Publication number
AR028676A1
AR028676A1 ARP010102663A ARP010102663A AR028676A1 AR 028676 A1 AR028676 A1 AR 028676A1 AR P010102663 A ARP010102663 A AR P010102663A AR P010102663 A ARP010102663 A AR P010102663A AR 028676 A1 AR028676 A1 AR 028676A1
Authority
AR
Argentina
Prior art keywords
antibodies
diagnosis
detection
deposited
appearance
Prior art date
Application number
ARP010102663A
Other languages
English (en)
Inventor
Gomez Luis Tomas Sorell
Castro Boris Ernesto Acevedo
Original Assignee
Ct Ingenieria Genetica Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotech filed Critical Ct Ingenieria Genetica Biotech
Publication of AR028676A1 publication Critical patent/AR028676A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Método no instrumental para el diagnostico de la enfermedad celíaca, basado en los principios generales de los ensayos inmunocromatográficos, de forma sencilla, rápida y confiable la deteccion de anticuerpos anti transglutinasa, tanto de clase IgA co mo IgG, en muestras de suero, plasma o sangre, a través de su reaccion con una sonda del antígeno transglutaminasa marcado por una sustancia coloreada como oro coloidal o partículas de latex coloreado, que se encuentra depositado sobre una matriz de la que es liberado al ponerse en cotnacto con muestras líquidas. Este inmunocomplejo migra a través de un soporte solido, como nitrocelulosa o nylon, el cual posee un poro que permite el flujo lateral de las sustancias reaccionantes, hasta que es a atrapado al interactuar con el propio antígeno trnasglutaminasa, que se encuentra firmemente unido a una zona reactiva del soporte. Debido a esta union el inmunocomplejo se deposita en el sitio de reaccion lo que seevidencia por la aparicion de una marca visualmente detectable en ese sitio, debido al color del marcador que forma parte del complejo. La aparicion de esta marca indica un resoltado positivo de la prueba a la presencia de anticuerpos anti transglutaminasa en la muestra analizada.
ARP010102663A 2000-06-07 2001-06-04 PROCEDIMIENTO PARA LA DETECCION DE ANTICUERPOS ANTITRANSGLUTAMINASA CON UTILIDAD EN EL DIAGNoSTICO DE LA ENFERMEDAD CELíACA AR028676A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20000132A CU22968A1 (es) 2000-06-07 2000-06-07 Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca

Publications (1)

Publication Number Publication Date
AR028676A1 true AR028676A1 (es) 2003-05-21

Family

ID=40287551

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010102663A AR028676A1 (es) 2000-06-07 2001-06-04 PROCEDIMIENTO PARA LA DETECCION DE ANTICUERPOS ANTITRANSGLUTAMINASA CON UTILIDAD EN EL DIAGNoSTICO DE LA ENFERMEDAD CELíACA

Country Status (14)

Country Link
US (1) US6905835B2 (es)
EP (1) EP1164375B1 (es)
AR (1) AR028676A1 (es)
AT (1) ATE335203T1 (es)
BR (1) BR0102281A (es)
CA (1) CA2349274C (es)
CU (1) CU22968A1 (es)
CY (1) CY1105739T1 (es)
DK (1) DK1164375T3 (es)
ES (1) ES2267662T3 (es)
MX (1) MXPA01005698A (es)
PT (1) PT1164375E (es)
RU (1) RU2214835C2 (es)
SI (1) SI1164375T1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2234086C2 (ru) * 2002-05-08 2004-08-10 Нижегородский научно-исследовательский институт детской гастроэнтерологии Способ дифференциальной диагностики целиакии и хронического энтерита у детей с патологией тонкой кишки
ES2214108B1 (es) * 2002-08-16 2005-11-16 Consejo Sup. Investig. Cientificas Sistema y procedimiento inmunocromatografico para la identificacion simultanea de anticuerpos frente a aga y t-tg, y su uso en el diagnostico de enfermedad celiaca.
FR2857453B1 (fr) * 2003-07-11 2007-04-20 Covalab Procede de detection serologique de la maladie coeliaque et necessaire de diagnostic associe
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
JP4982107B2 (ja) * 2006-04-28 2012-07-25 アルフレッサファーマ株式会社 免疫学的微小粒子の凝集反応を用いる検体の測定方法および測定用キット
EP2049903B1 (en) 2006-07-25 2015-09-09 Augurix S.A. An immunochromatography device for the diagnosis of diseases in a sample
US7935538B2 (en) * 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
RU2333491C1 (ru) * 2007-01-16 2008-09-10 Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургская государственная медицинская академия им. И.И. Мечникова Федерального агентства по здравоохранению и социальному развитию" Способ диагностики целиакии
US20100022916A1 (en) 2008-07-24 2010-01-28 Javanbakhsh Esfandiari Method and Apparatus for Collecting and Preparing Biological Samples for Testing
US20100290948A1 (en) * 2009-05-15 2010-11-18 Xuedong Song Absorbent articles capable of indicating the presence of urinary tract infections
CN107831318B (zh) * 2011-01-20 2021-06-18 西瑞斯实验室有限公司 检测谷蛋白敏感性和其区分于乳糜泻的方法和装置
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
NL1039468C2 (nl) * 2012-03-15 2013-09-18 Maria Johanna Kousemaker Glutensensitiviteit bij het paard (equine gse).
SG11201608278WA (en) 2014-04-02 2016-10-28 Chembio Diagnostic Systems Inc Immunoassay utilizing trapping conjugate
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
CN119310275B (zh) * 2024-12-13 2025-03-21 中南大学湘雅二医院 一种用于大疱性皮肤病亚型鉴定的水凝胶微针贴片、制造方法及使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012494A (en) * 1971-12-21 1977-03-15 Abbott Laboratories Direct radioimmunoassay for antigens and their antibodies
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
DE19630557C2 (de) * 1996-07-18 1998-07-02 Schuppan Detlef Priv Doz Dr Dr Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie
RU2137134C1 (ru) * 1997-04-15 1999-09-10 Учебно-научный центр Медицинского центра при Правительстве Российской Федерации Способ количественного определения аутоантител к липопротеидам низкой плотности в сыворотке крови
WO2001029090A1 (en) * 1999-10-20 2001-04-26 Immco Diagnostics Immunological assay for detection of antibodies in celiac disease
US6667160B2 (en) * 2000-03-15 2003-12-23 Kenneth D. Fine Method for diagnosing immunologic food sensitivity

Also Published As

Publication number Publication date
MXPA01005698A (es) 2003-08-20
PT1164375E (pt) 2006-12-29
EP1164375A3 (en) 2002-09-25
EP1164375A2 (en) 2001-12-19
EP1164375B1 (en) 2006-08-02
ATE335203T1 (de) 2006-08-15
RU2214835C2 (ru) 2003-10-27
CA2349274A1 (en) 2001-12-07
CU22968A1 (es) 2004-07-14
CY1105739T1 (el) 2010-12-22
US6905835B2 (en) 2005-06-14
BR0102281A (pt) 2002-02-19
ES2267662T3 (es) 2007-03-16
US20020006633A1 (en) 2002-01-17
SI1164375T1 (sl) 2006-12-31
CA2349274C (en) 2009-08-25
DK1164375T3 (da) 2006-12-04

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